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Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo

ACS nano, 2015-09, Vol.9 (9), p.9217-9227

2015

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Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus

Journal of controlled release, 2013-09, Vol.170 (2), p.279-286

2013

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Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo

Journal of controlled release, 2013-04, Vol.167 (1), p.76-84

2013

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Lung gene therapy with highly compacted DNA nanoparticles that overcome the mucus barrier

Journal of controlled release, 2014-03, Vol.178, p.8-17

2014

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Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats

Journal of controlled release, 2015-03, Vol.201, p.32-40

2015

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Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

Science advances, 2017-04, Vol.3 (4), p.e1601556-e1601556

2017

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Conjugation Site Heterogeneity Causes Variable Electrostatic Properties in Fc Conjugates

Bioconjugate chemistry, 2013-06, Vol.24 (6), p.1008-1016

2013

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Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine

Nanomedicine (London, England), 2011-02, Vol.6 (2), p.365-375

2011

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Highly compacted DNA nanoparticles with low MW PEG coatings: In vitro, ex vivo and in vivo evaluation

Journal of controlled release, 2012-01, Vol.157 (1), p.72-79

2012

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Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly- l -lysine

Biomaterials, 2012-03, Vol.33 (7), p.2361-2371

2012

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Use of Single-Site-Functionalized PEG Dendrons To Prepare Gene Vectors that Penetrate Human Mucus Barriers

Angewandte Chemie (International ed.), 2013-04, Vol.52 (14), p.3985-3988

International ed. in English, 2013

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N-acetylcysteine Enhances Cystic Fibrosis Sputum Penetration and Airway Gene Transfer by Highly Compacted DNA Nanoparticles

Molecular therapy, 2011-11, Vol.19 (11), p.1981-1989

2011

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Non-degradative intracellular trafficking of highly compacted polymeric DNA nanoparticles

Journal of controlled release, 2012-02, Vol.158 (1), p.102-107

2012

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DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma

Journal of controlled release, 2014-04, Vol.180, p.125-133

2014

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Highly compacted pH-responsive DNA nanoparticles mediate transgene silencing in experimental glioma

Journal of materials chemistry. B, Materials for biology and medicine, 2014-12, Vol.2 (46), p.8165-8173

2014

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Use of Single‐Site‐Functionalized PEG Dendrons To Prepare Gene Vectors that Penetrate Human Mucus Barriers

Angewandte Chemie, 2013-04, Vol.125 (14), p.4077-4080

2013

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A novel in situ hydrophobic ion paring (HIP) formulation strategy for clinical product selection of a nanoparticle drug delivery system

Journal of controlled release, 2016-05, Vol.229, p.106-119

2016

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A novel in situ hydrophobic ion pairing (HIP) formulation strategy for clinical product selection of a nanoparticle drug delivery system

Journal of controlled release, 2016-05, Vol.229, p.106-119

2016

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Celebrity/Employee Confidentiality Agreements: How to Make Them Work

Entertainment and sports law journal (Coventry, England), 2016-06, Vol.4 (2)

Boylan, Paul Nicholas

2016

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New nanoparticle-based systems for pulmonary drug and gene delivery

Boylan, Nicholas

2012

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Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with

Nanomedicine (London, England), 2011-02, Vol.6 (2), p.365-375

2011

Volltextzugriff (PDF)

Use of Single-Site-Functionalized PEG Dendrons To Prepare Gene Vectors that Penetrate Human Mucus Barriers

Angewandte Chemie, 2013-04, Vol.125 (14), p.4077-4080

2013

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Time course of expression and function of the serotonin transporter in the neonatal rat's primary somatosensory cortex

Somatosensory & motor research, 2000, Vol.17 (1), p.52-60

2000

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Coronary CT Angiography and 5-Year Risk of Myocardial Infarction

The New England journal of medicine, 2018-09, Vol.379 (10), p.924-933

2018

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TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

Nature neuroscience, 2018-02, Vol.21 (2), p.228-239

2018

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Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo

Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus

Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo

Lung gene therapy with highly compacted DNA nanoparticles that overcome the mucus barrier

Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats

Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

Conjugation Site Heterogeneity Causes Variable Electrostatic Properties in Fc Conjugates

Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine

Highly compacted DNA nanoparticles with low MW PEG coatings: In vitro, ex vivo and in vivo evaluation

Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly- l -lysine

Use of Single-Site-Functionalized PEG Dendrons To Prepare Gene Vectors that Penetrate Human Mucus Barriers

N-acetylcysteine Enhances Cystic Fibrosis Sputum Penetration and Airway Gene Transfer by Highly Compacted DNA Nanoparticles

Non-degradative intracellular trafficking of highly compacted polymeric DNA nanoparticles

DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma

Highly compacted pH-responsive DNA nanoparticles mediate transgene silencing in experimental glioma

Use of Single‐Site‐Functionalized PEG Dendrons To Prepare Gene Vectors that Penetrate Human Mucus Barriers

A novel in situ hydrophobic ion paring (HIP) formulation strategy for clinical product selection of a nanoparticle drug delivery system

A novel in situ hydrophobic ion pairing (HIP) formulation strategy for clinical product selection of a nanoparticle drug delivery system

Celebrity/Employee Confidentiality Agreements: How to Make Them Work

New nanoparticle-based systems for pulmonary drug and gene delivery

Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with

Use of Single-Site-Functionalized PEG Dendrons To Prepare Gene Vectors that Penetrate Human Mucus Barriers

Time course of expression and function of the serotonin transporter in the neonatal rat's primary somatosensory cortex

Coronary CT Angiography and 5-Year Risk of Myocardial Infarction

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

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