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SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond

Trends in biochemical sciences (Amsterdam. Regular ed.), 2018-05, Vol.43 (5), p.358-368

2018

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The Nobel history of computational chemistry. A personal perspective

Journal of computational chemistry, 2024-08, Vol.45 (22), p.1921-1935

Boyd, Russell J

2024

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The Quantum Theory of Atoms in Molecules: From Solid State to DNA and Drug Design

1, 2007

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Significance and regulation of lipid metabolism

Seminars in cell & developmental biology, 2018-09, Vol.81, p.97-97

DeBose-Boyd, Russell A.

2018

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Posttranslational Regulation of HMG CoA Reductase, the Rate-Limiting Enzyme in Synthesis of Cholesterol

Annual review of biochemistry, 2021-06, Vol.90 (1), p.659-679

2021

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Post-Translational Regulation of HMG CoA Reductase

Cold Spring Harbor perspectives in biology, 2022-12, Vol.14 (12), p.a041253

2022

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Feedback regulation of cholesterol synthesis： sterol-accelerated ubiquitination and degradation of HMG CoA reductase

Cell research, 2008-06, Vol.18 (6), p.609-621

Russell A DeBose-Boyd

2008

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Underlying mechanisms for sterol-induced ubiquitination and ER-associated degradation of HMG CoA reductase

Seminars in cell & developmental biology, 2018-09, Vol.81, p.121-128

2018

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Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver

The Journal of biological chemistry, 2017-06, Vol.292 (22), p.9382-9393

2017

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Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase

Critical reviews in biochemistry and molecular biology, 2010-06, Vol.45 (3), p.185-198

2010

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Direct binding to sterols accelerates endoplasmic reticulum-associated degradation of HMG CoA reductase

Proceedings of the National Academy of Sciences - PNAS, 2024-02, Vol.121 (7), p.e2318822121

2024

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Regulation of cholesterol and fatty acid synthesis

Cold Spring Harbor perspectives in biology, 2011-07, Vol.3 (7), p.a004754-a004754

2011

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The Vitamin K 2 Synthetic Enzyme UBIAD1 Moonlights as a Key Regulator of Cholesterol Synthesis

The FASEB journal, 2022-05, Vol.36 Suppl 1 (S1)

2022

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Multiple Dietary Vitamin K Forms Are Converted to Tissue Menaquinone-4 in Mice

The Journal of nutrition, 2022-04, Vol.152 (4), p.981-993

2022

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Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain

Nature communications, 2022-07, Vol.13 (1), p.4273-12, Article 4273

2022

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Computational Study of Engineered Cytochrome P450-Catalyzed C–H Amination: The Origin of the Regio- and Stereoselectivity

The journal of physical chemistry. B, 2017-12, Vol.121 (48), p.10859-10868

2017

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Hydrogen Bond Cooperativity in Water Hexamers: Atomic Energy Perspective of Local Stabilities

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2013-10, Vol.117 (41), p.10790-10799

2013

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Protein Sensors for Membrane Sterols

Cell, 2006-01, Vol.124 (1), p.35-46

2006

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A Density Functional Study of Methanol Clusters

Journal of chemical theory and computation, 2007-01, Vol.3 (1), p.54-61

2007

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Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes

Molecular biology of the cell, 2013-02, Vol.24 (3), p.169-183

2013

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The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase

eLife, 2015-03, Vol.4

2015

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Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (51), p.20503-20508

2011

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Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

The Journal of biological chemistry, 2011-04, Vol.286 (17), p.15022-15031

2011

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Introduction to the WATOC Special Issue

Canadian journal of chemistry, 2023-09, Vol.101 (9), p.578-578

2023

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Changing Weak Halogen Bonds into Strong Ones through Cooperativity with Beryllium Bonds

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2014-06, Vol.118 (23), p.4205-4213

2014

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SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond

The Nobel history of computational chemistry. A personal perspective

The Quantum Theory of Atoms in Molecules: From Solid State to DNA and Drug Design

Significance and regulation of lipid metabolism

Posttranslational Regulation of HMG CoA Reductase, the Rate-Limiting Enzyme in Synthesis of Cholesterol

Post-Translational Regulation of HMG CoA Reductase

Feedback regulation of cholesterol synthesis： sterol-accelerated ubiquitination and degradation of HMG CoA reductase

Underlying mechanisms for sterol-induced ubiquitination and ER-associated degradation of HMG CoA reductase

Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver

Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase

Direct binding to sterols accelerates endoplasmic reticulum-associated degradation of HMG CoA reductase

Regulation of cholesterol and fatty acid synthesis

The Vitamin K 2 Synthetic Enzyme UBIAD1 Moonlights as a Key Regulator of Cholesterol Synthesis

Multiple Dietary Vitamin K Forms Are Converted to Tissue Menaquinone-4 in Mice

Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain

Computational Study of Engineered Cytochrome P450-Catalyzed C–H Amination: The Origin of the Regio- and Stereoselectivity

Hydrogen Bond Cooperativity in Water Hexamers: Atomic Energy Perspective of Local Stabilities

Protein Sensors for Membrane Sterols

A Density Functional Study of Methanol Clusters

Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

Introduction to the WATOC Special Issue

Changing Weak Halogen Bonds into Strong Ones through Cooperativity with Beryllium Bonds

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