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Why Clinical Modulation of Efflux Transport at the Human Blood-Brain Barrier Is Unlikely: The ITC Evidence-Based Position

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.80-94

2013

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Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.916-932

2018

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Electric-field tuning of the valley splitting in silicon corner dots

Applied physics letters, 2018-07, Vol.113 (5)

2018

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Biotransformation and bioactivation reactions of alicyclic amines in drug molecules

Drug metabolism reviews, 2014-08, Vol.46 (3), p.379-419

2014

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Mechanisms underlying saturable intestinal absorption of metformin

Drug metabolism and disposition, 2008-08, Vol.36 (8), p.1650-1658

2008

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Phase I study in healthy participants to evaluate safety, tolerability, and pharmacokinetics of inhaled nezulcitinib, a potential treatment for COVID‐19

Clinical and translational science, 2021-11, Vol.14 (6), p.2556-2565

2021

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Pauli blockade in a few-hole PMOS double quantum dot limited by spin-orbit interaction

Applied physics letters, 2016-11, Vol.109 (19)

2016

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Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)

The Journal of pharmacology and experimental therapeutics, 2005-12, Vol.315 (3), p.1288-1297

2005

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Pharmacokinetics and safety of revefenacin in subjects with impaired renal or hepatic function

International journal of chronic obstructive pulmonary disease, 2019-10, Vol.14, p.2305-2318

2019

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Efficacy and safety of an inhaled pan-Janus kinase inhibitor, nezulcitinib, in hospitalised patients with COVID-19: results from a phase 2 clinical trial

BMJ open respiratory research, 2023-07, Vol.10 (1), p.e001627

2023

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High-efficiency diode-pumped femtosecond Yb:YAG ceramic laser

Optics letters, 2010-02, Vol.35 (3), p.288

2010

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Time and Spectrum Resolved Model for Quasi-Three-Level Gain-Switched Lasers

IEEE journal of quantum electronics, 2007-02, Vol.43 (2), p.206-212

2007

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Population Pharmacokinetics of Revefenacin in Patients with Chronic Obstructive Pulmonary Disease

Clinical pharmacokinetics, 2021-03, Vol.60 (3), p.391-401

2021

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A phase 2 multiple ascending dose study of the inhaled pan-JAK inhibitor nezulcitinib (TD-0903) in severe COVID-19

The European respiratory journal, 2021-10, Vol.58 (4), p.2100673

2021

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Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes

The Journal of pharmacology and experimental therapeutics, 2006-09, Vol.318 (3), p.1068-1075

2006

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Hepatic Dysfunction Quantified by HepQuant DuO Outperforms Child‐Pugh Classification in Predicting the Pharmacokinetics of Ampreloxetine

Clinical pharmacology and therapeutics, 2024-07, Vol.116 (1), p.186-193

2024

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Prediction of human serotonin and norepinephrine transporter occupancy of duloxetine by pharmacokinetic/pharmacodynamic modeling in the rat

The Journal of pharmacology and experimental therapeutics, 2012-04, Vol.341 (1), p.137-145

2012

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Pharmacokinetics of Ampreloxetine, a Norepinephrine Reuptake Inhibitor, in Healthy Subjects and Adults with Attention-Deficit/Hyperactive Disorder or Fibromyalgia Pain

Clinical pharmacokinetics, 2021-01, Vol.60 (1), p.121-131

2021

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Saturable absorptive transport of the hydrophilic organic cation ranitidine in Caco-2 cells: role of pH-dependent organic cation uptake system and P-glycoprotein

Pharmaceutical research, 2006-06, Vol.23 (6), p.1165-1177

2006

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Theoretical analysis of an end-pumped Yb:YAG active mirror thin-disk amplifier with a longitudinal doping concentration gradient

Applied Optics, 2014-11, Vol.53 (31), p.7556

2014

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Overview of Causality Assessment for Drug-Induced Liver Injury (DILI) in Clinical Trials

Drug safety, 2021-06, Vol.44 (6), p.619-634

2021

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Stacked nanowires/nanosheets GAA MOSFET from technology to design enablement

2017 International Conference on Simulation of Semiconductor Processes and Devices (SISPAD), 2017, p.5-8

2017

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Revefenacin Absorption, Metabolism, and Excretion in Healthy Subjects and Pharmacological Activity of Its Major Metabolite

Drug metabolism and disposition, 2020-12, Vol.48 (12), p.1312-1320

2020

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Gut-Selective Design of Orally Administered Izencitinib (TD-1473) Limits Systemic Exposure and Effects of Janus Kinase Inhibition in Nonclinical Species

Toxicological sciences, 2022-03, Vol.186 (2), p.323-337

2022

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Pharmacodynamics, pharmacokinetics and safety of revefenacin (TD-4208), a long-acting muscarinic antagonist, in patients with chronic obstructive pulmonary disease (COPD): Results of two randomized, double-blind, phase 2 studies

Pulmonary pharmacology & therapeutics, 2018-02, Vol.48, p.71-79

2018

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Why Clinical Modulation of Efflux Transport at the Human Blood-Brain Barrier Is Unlikely: The ITC Evidence-Based Position

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

Electric-field tuning of the valley splitting in silicon corner dots

Biotransformation and bioactivation reactions of alicyclic amines in drug molecules

Mechanisms underlying saturable intestinal absorption of metformin

Phase I study in healthy participants to evaluate safety, tolerability, and pharmacokinetics of inhaled nezulcitinib, a potential treatment for COVID‐19

Pauli blockade in a few-hole PMOS double quantum dot limited by spin-orbit interaction

Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)

Pharmacokinetics and safety of revefenacin in subjects with impaired renal or hepatic function

Efficacy and safety of an inhaled pan-Janus kinase inhibitor, nezulcitinib, in hospitalised patients with COVID-19: results from a phase 2 clinical trial

High-efficiency diode-pumped femtosecond Yb:YAG ceramic laser

Time and Spectrum Resolved Model for Quasi-Three-Level Gain-Switched Lasers

Population Pharmacokinetics of Revefenacin in Patients with Chronic Obstructive Pulmonary Disease

A phase 2 multiple ascending dose study of the inhaled pan-JAK inhibitor nezulcitinib (TD-0903) in severe COVID-19

Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes

Hepatic Dysfunction Quantified by HepQuant DuO Outperforms Child‐Pugh Classification in Predicting the Pharmacokinetics of Ampreloxetine

Prediction of human serotonin and norepinephrine transporter occupancy of duloxetine by pharmacokinetic/pharmacodynamic modeling in the rat

Pharmacokinetics of Ampreloxetine, a Norepinephrine Reuptake Inhibitor, in Healthy Subjects and Adults with Attention-Deficit/Hyperactive Disorder or Fibromyalgia Pain

Saturable absorptive transport of the hydrophilic organic cation ranitidine in Caco-2 cells: role of pH-dependent organic cation uptake system and P-glycoprotein

Theoretical analysis of an end-pumped Yb:YAG active mirror thin-disk amplifier with a longitudinal doping concentration gradient

Overview of Causality Assessment for Drug-Induced Liver Injury (DILI) in Clinical Trials

Stacked nanowires/nanosheets GAA MOSFET from technology to design enablement

Revefenacin Absorption, Metabolism, and Excretion in Healthy Subjects and Pharmacological Activity of Its Major Metabolite

Gut-Selective Design of Orally Administered Izencitinib (TD-1473) Limits Systemic Exposure and Effects of Janus Kinase Inhibition in Nonclinical Species

Pharmacodynamics, pharmacokinetics and safety of revefenacin (TD-4208), a long-acting muscarinic antagonist, in patients with chronic obstructive pulmonary disease (COPD): Results of two randomized, double-blind, phase 2 studies

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