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Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain

The Journal of pharmacology and experimental therapeutics, 2009-09, Vol.330 (3), p.902

2009

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Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

Nature (London), 1996-11, Vol.384 (6604), p.83-87

1996

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A Simple, High-Resolution Method for Establishing DNA Binding Affinity and Sequence Selectivity

Journal of the American Chemical Society, 2001-06, Vol.123 (25), p.5878-5891

2001

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Asymmetric Total Synthesis of ent-(−)-Roseophilin: Assignment of Absolute Configuration

Journal of the American Chemical Society, 2001-09, Vol.123 (35), p.8515-8519

2001

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Total Synthesis of Fostriecin (CI-920)

Journal of the American Chemical Society, 2001-05, Vol.123 (18), p.4161-4167

2001

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Fostriecin: chemistry and biology

Current medicinal chemistry, 2002-11, Vol.9 (22), p.2005

2002

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Chemical characterization of a family of brain lipids that induce sleep

Science (American Association for the Advancement of Science), 1995-06, Vol.268 (5216), p.1506-1509

1995

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First and Second Generation Total Synthesis of the Teicoplanin Aglycon

Journal of the American Chemical Society, 2001-03, Vol.123 (9), p.1862-1871

2001

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Total Synthesis of Amaryllidaceae Alkaloids Utilizing Sequential Intramolecular Heterocyclic Azadiene Diels−Alder Reactions of an Unsymmetrical 1,2,4,5-Tetrazine

Journal of organic chemistry, 2000-12, Vol.65 (26), p.9120-9124

2000

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CC-1065 and the Duocarmycins: Unraveling the Keys to a New Class of Naturally Derived DNA Alkylating Agents

Proceedings of the National Academy of Sciences - PNAS, 1995-04, Vol.92 (9), p.3642-3649

1995

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Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

Nature biotechnology, 2003-06, Vol.21 (6), p.687-691

2003

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Total Syntheses of Thiocoraline and BE-22179 and Assessment of Their DNA Binding and Biological Properties

Journal of the American Chemical Society, 2001-01, Vol.123 (4), p.561-568

2001

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Discovery of a Potent, Selective, and Efficacious Class of Reversible α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Effective as Analgesics

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.1849-1856

2005

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Selective Metal Cation Activation of a DNA Alkylating Agent: Synthesis and Evaluation of Methyl 1,2,9,9a-Tetrahydrocyclopropa[c]pyrido[3,2-e]indol-4-one-7-carboxylate (CPyI)

Journal of organic chemistry, 2000-06, Vol.65 (13), p.4088-4100

2000

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Vancomycin, teicoplanin, and ramoplanin: Synthetic and mechanistic studies

Medicinal research reviews, 2001-09, Vol.21 (5), p.356-381

Boger, Dale L.

2001

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Small-Molecule Antagonists of Myc/Max Dimerization Inhibit Myc-Induced Transformation of Chicken Embryo Fibroblasts

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (6), p.3830-3835

2002

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Trifluoromethyl ketone inhibitors of fatty acid amide hydrolase: A probe of structural and conformational features contributing to inhibition

Bioorganic & medicinal chemistry letters, 1999-01, Vol.9 (2), p.265-270

1999

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Synthesis and Evaluation of a Series of C3-Substituted CBI Analogues of CC-1065 and the Duocarmycins

Journal of organic chemistry, 2001-07, Vol.66 (15), p.5163-5173

2001

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Unexpected Formation of an Epoxide-Derived Multisubstrate Adduct Inhibitor on the Active Site of GAR Transformylase

Biochemistry (Easton), 2001-11, Vol.40 (45), p.13538-13547

2001

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Total Synthesis of Distamycin A and 2640 Analogues: A Solution-Phase Combinatorial Approach to the Discovery of New, Bioactive DNA Binding Agents and Development of a Rapid, High-Throughput Screen for Determining Relative DNA Binding Affinity or DNA Binding Sequence Selectivity

Journal of the American Chemical Society, 2000-07, Vol.122 (27), p.6382-6394

2000

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Parallel Synthesis and Evaluation of 132 (+)-1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) Analogues of CC-1065 and the Duocarmycins Defining the Contribution of the DNA-Binding Domain

Journal of organic chemistry, 2001-10, Vol.66 (20), p.6654-6661

2001

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Exceptionally Potent Inhibitors of Fatty Acid Amide Hydrolase: The Enzyme Responsible for Degradation of Endogenous Oleamide and Anandamide

Proceedings of the National Academy of Sciences - PNAS, 2000-05, Vol.97 (10), p.5044-5049

2000

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Reversibility of the duocarmycin A and SA DNA alkylation reaction

Journal of the American Chemical Society, 1993-10, Vol.115 (21), p.9872-9873

1993

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DNA Alkylation Properties of Yatakemycin

Journal of the American Chemical Society, 2003-09, Vol.125 (36), p.10971-10976

2003

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Metal Cation Complexation and Activation of Reversed CPyI Analogues of CC-1065 and Duocarmycin SA: Partitioning the Effects of Binding and Catalysis

Journal of the American Chemical Society, 2001-09, Vol.123 (38), p.9299-9306

2001

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Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

A Simple, High-Resolution Method for Establishing DNA Binding Affinity and Sequence Selectivity

Asymmetric Total Synthesis of ent-(−)-Roseophilin: Assignment of Absolute Configuration

Total Synthesis of Fostriecin (CI-920)

Fostriecin: chemistry and biology

Chemical characterization of a family of brain lipids that induce sleep

First and Second Generation Total Synthesis of the Teicoplanin Aglycon

Total Synthesis of Amaryllidaceae Alkaloids Utilizing Sequential Intramolecular Heterocyclic Azadiene Diels−Alder Reactions of an Unsymmetrical 1,2,4,5-Tetrazine

CC-1065 and the Duocarmycins: Unraveling the Keys to a New Class of Naturally Derived DNA Alkylating Agents

Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

Total Syntheses of Thiocoraline and BE-22179 and Assessment of Their DNA Binding and Biological Properties

Discovery of a Potent, Selective, and Efficacious Class of Reversible α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Effective as Analgesics

Selective Metal Cation Activation of a DNA Alkylating Agent: Synthesis and Evaluation of Methyl 1,2,9,9a-Tetrahydrocyclopropa[c]pyrido[3,2-e]indol-4-one-7-carboxylate (CPyI)

Vancomycin, teicoplanin, and ramoplanin: Synthetic and mechanistic studies

Small-Molecule Antagonists of Myc/Max Dimerization Inhibit Myc-Induced Transformation of Chicken Embryo Fibroblasts

Trifluoromethyl ketone inhibitors of fatty acid amide hydrolase: A probe of structural and conformational features contributing to inhibition

Synthesis and Evaluation of a Series of C3-Substituted CBI Analogues of CC-1065 and the Duocarmycins

Unexpected Formation of an Epoxide-Derived Multisubstrate Adduct Inhibitor on the Active Site of GAR Transformylase

Total Synthesis of Distamycin A and 2640 Analogues: A Solution-Phase Combinatorial Approach to the Discovery of New, Bioactive DNA Binding Agents and Development of a Rapid, High-Throughput Screen for Determining Relative DNA Binding Affinity or DNA Binding Sequence Selectivity

Parallel Synthesis and Evaluation of 132 (+)-1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) Analogues of CC-1065 and the Duocarmycins Defining the Contribution of the DNA-Binding Domain

Exceptionally Potent Inhibitors of Fatty Acid Amide Hydrolase: The Enzyme Responsible for Degradation of Endogenous Oleamide and Anandamide

Reversibility of the duocarmycin A and SA DNA alkylation reaction

DNA Alkylation Properties of Yatakemycin

Metal Cation Complexation and Activation of Reversed CPyI Analogues of CC-1065 and Duocarmycin SA: Partitioning the Effects of Binding and Catalysis

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