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Linking complement and anti-dsDNA antibodies in the pathogenesis of systemic lupus erythematosus

Immunologic research, 2013-03, Vol.55 (1-3), p.10-21

2013

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Evaluation of RNase therapy in systemic lupus erythematosus: a randomised phase 2a clinical trial of RSLV-132

Lupus science & medicine, 2024-02, Vol.11 (1), p.e001113

2024

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Regulatory Architecture of the RCA Gene Cluster Captures an Intragenic TAD Boundary, CTCF-Mediated Chromatin Looping and a Long-Range Intergenic Enhancer

Frontiers in immunology, 2022-06, Vol.13, p.901747-901747

2022

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Elevated Detection of Dual Antibody B Cells Identifies Lupus Patients With B Cell-Reactive VH4-34 Autoantibodies

Frontiers in immunology, 2022-02, Vol.13, p.795209-795209

2022

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Better Biomarkers for Lupus Disease Activity: Tools for Treating to Target

Arthritis & rheumatology (Hoboken, N.J.), 2019-03, Vol.71 (3), p.329-330

Boackle, Susan A.

2019

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Phase II Randomized Trial of Rituximab Plus Cyclophosphamide Followed by Belimumab for the Treatment of Lupus Nephritis

Arthritis & rheumatology (Hoboken, N.J.), 2021-01, Vol.73 (1), p.121-131

2021

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Cr2, a Candidate Gene in the Murine Sle1c Lupus Susceptibility Locus, Encodes a Dysfunctional Protein

Immunity (Cambridge, Mass.), 2001-11, Vol.15 (5), p.775-785

2001

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Advances in lupus genetics

Current opinion in rheumatology, 2013-09, Vol.25 (5), p.561-568

Boackle, Susan A

2013

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Modulation of Renal Disease in MRL/lpr Mice Genetically Deficient in the Alternative Complement Pathway Factor B

The Journal of immunology (1950), 2000-01, Vol.164 (2), p.786-794

2000

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Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells

Cellular & molecular immunology, 2016-01, Vol.13 (1), p.119-131

2016

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Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice

Proceedings of the National Academy of Sciences - PNAS, 2021-04, Vol.118 (16), p.1-12

2021

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Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (10), p.3961-3966

2007

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Editorial: Subduing Lupus: Can Preclinical Autoimmune Disease Be Arrested?

Arthritis & rheumatology (Hoboken, N.J.), 2016-10, Vol.68 (10), p.2357-2360

2016

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Absence of T Cells Confers Increased Pulmonary Arterial Hypertension and Vascular Remodeling

American journal of respiratory and critical care medicine, 2007-06, Vol.175 (12), p.1280-1289

2007

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Arthritis Critically Dependent on Innate Immune System Players

Immunity (Cambridge, Mass.), 2002-02, Vol.16 (2), p.157-168

2002

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Intrinsic B cell hypo‐responsiveness in mice prematurely expressing human CR2/CD21 during B cell development

European Journal of Immunology, 2007-03, Vol.37 (3), p.623-633

2007

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IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity

The Journal of immunology (1950), 2011-09, Vol.187 (5), p.2101-2111

2011

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Transcriptional effects of a lupus-associated polymorphism in the 5′ untranslated region (UTR) of human complement receptor 2 (CR2/CD21)

Molecular immunology, 2012-10, Vol.52 (3-4), p.165-173

2012

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Complement and autoimmunity

Biomedicine & pharmacotherapy, 2003-09, Vol.57 (7), p.269-273

Boackle, Susan A.

2003

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Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis

American journal of physiology. Renal physiology, 2012-06, Vol.302 (12), p.F1529-F1536

2012

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Complement Component C3 Is Not Required for Full Expression of Immune Complex Glomerulonephritis in MRL/lpr Mice

The Journal of immunology (1950), 2001-05, Vol.166 (10), p.6444-6451

2001

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An allelic variant of Crry in the murine Sle1c lupus susceptibility interval is not impaired in its ability to regulate complement activation

The Journal of immunology (1950), 2010-08, Vol.185 (4), p.2331-2339

2010

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Transgenic Expression of a Soluble Complement Inhibitor Protects Against Renal Disease and Promotes Survival in MRL/lpr Mice

The Journal of immunology (1950), 2002-04, Vol.168 (7), p.3601-3607

2002

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Several Genes Contribute to the Production of Autoreactive B and T Cells in the Murine Lupus Susceptibility Locus Sle1c

The Journal of immunology (1950), 2005-07, Vol.175 (2), p.1080-1089

2005

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Linking complement and anti-dsDNA antibodies in the pathogenesis of systemic lupus erythematosus

Evaluation of RNase therapy in systemic lupus erythematosus: a randomised phase 2a clinical trial of RSLV-132

Regulatory Architecture of the RCA Gene Cluster Captures an Intragenic TAD Boundary, CTCF-Mediated Chromatin Looping and a Long-Range Intergenic Enhancer

Elevated Detection of Dual Antibody B Cells Identifies Lupus Patients With B Cell-Reactive VH4-34 Autoantibodies

Better Biomarkers for Lupus Disease Activity: Tools for Treating to Target

Phase II Randomized Trial of Rituximab Plus Cyclophosphamide Followed by Belimumab for the Treatment of Lupus Nephritis

Cr2, a Candidate Gene in the Murine Sle1c Lupus Susceptibility Locus, Encodes a Dysfunctional Protein

Advances in lupus genetics

Modulation of Renal Disease in MRL/lpr Mice Genetically Deficient in the Alternative Complement Pathway Factor B

Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells

Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice

Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus

Editorial: Subduing Lupus: Can Preclinical Autoimmune Disease Be Arrested?

Absence of T Cells Confers Increased Pulmonary Arterial Hypertension and Vascular Remodeling

Arthritis Critically Dependent on Innate Immune System Players

Intrinsic B cell hypo‐responsiveness in mice prematurely expressing human CR2/CD21 during B cell development

IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity

Transcriptional effects of a lupus-associated polymorphism in the 5′ untranslated region (UTR) of human complement receptor 2 (CR2/CD21)

Complement and autoimmunity

Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis

Complement Component C3 Is Not Required for Full Expression of Immune Complex Glomerulonephritis in MRL/lpr Mice

Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry

An allelic variant of Crry in the murine Sle1c lupus susceptibility interval is not impaired in its ability to regulate complement activation

Transgenic Expression of a Soluble Complement Inhibitor Protects Against Renal Disease and Promotes Survival in MRL/lpr Mice

Several Genes Contribute to the Production of Autoreactive B and T Cells in the Murine Lupus Susceptibility Locus Sle1c

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