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Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells

Cell stem cell, 2016-09, Vol.19 (3), p.406-414

2016

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Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens

Cell reports (Cambridge), 2020-12, Vol.33 (9), p.108460-108460, Article 108460

2020

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Editing the epigenome: technologies for programmable transcription and epigenetic modulation

Nature methods, 2016-02, Vol.13 (2), p.127-137

2016

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CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

Nature biotechnology, 2017-06, Vol.35 (6), p.561-568

2017

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Mammalian Synthetic Biology: Engineering Biological Systems

Annual review of biomedical engineering, 2017-06, Vol.19 (1), p.249-277

2017

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Synthetic transcription factors for cell fate reprogramming

Current opinion in genetics & development, 2018-10, Vol.52, p.13-21

2018

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Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells

Nature biotechnology, 2019-12, Vol.37 (12), p.1493-1501

2019

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CRISPR-based methods for high-throughput annotation of regulatory DNA

Current opinion in biotechnology, 2018-08, Vol.52, p.32-41

2018

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Results of the Two Incidence Screenings in the National Lung Screening Trial

The New England journal of medicine, 2013-09, Vol.369 (10), p.920-931

2013

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Combinatorial Regulation of Endothelial Gene Expression by Ets and Forkhead Transcription Factors

Cell, 2008-12, Vol.135 (6), p.1053-1064

2008

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Prostate Cancer Screening in the Randomized Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial: Mortality Results after 13 Years of Follow-up

JNCI : Journal of the National Cancer Institute, 2012-01, Vol.104 (2), p.125-132

2012

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Transcriptomic analysis of AHR wildtype and Knock-out rat livers supports TCDD's role in AHR/ARNT-mediated circadian disruption and hepatotoxicity

Toxicology and applied pharmacology, 2024-06, Vol.487, p.116956, Article 116956

2024

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Baseline Plasma Tumor Mutation Burden Predicts Response to Pembrolizumab-based Therapy in Patients with Metastatic Non-Small Cell Lung Cancer

Clinical cancer research, 2020-05, Vol.26 (10), p.2354-2361

2020

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Intensity‐modulated radiotherapy with planned Gamma Knife radiosurgery boost for head and neck cancer with extensive disease in proximity to critical structures

Head & neck, 2022-11, Vol.44 (11), p.2571-2578

2022

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Characteristics of poisonings involving ketamine in the United States, 2019–2021

Journal of psychopharmacology (Oxford), 2023-08, Vol.37 (8), p.802-808

2023

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LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Nature genetics, 2015-03, Vol.47 (3), p.291-295

2015

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Effect of screening on ovarian cancer mortality: the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Randomized Controlled Trial

JAMA : the journal of the American Medical Association, 2011-06, Vol.305 (22), p.2295

2011

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Prospective validation of a risk score to predict pacemaker implantation after transcatheter aortic valve replacement

Journal of cardiovascular electrophysiology, 2023-11, Vol.34 (11), p.2225-2232

2023

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Characteristics of HIV seroconverters in the setting of universal test and treat: Results from the SEARCH trial in rural Uganda and Kenya

PloS one, 2021-02, Vol.16 (2), p.e0243167-e0243167

2021

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Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development

Development (Cambridge), 2004-08, Vol.131 (16), p.3931-3942

2004

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Perioperative Outcomes of Open versus Endovascular Repair for Ruptured Thoracoabdominal Aneurysms

Annals of vascular surgery, 2017-10, Vol.44, p.128-135

2017

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Stressful Life Events and Depression Symptoms: The Effect of Childhood Emotional Abuse on Stress Reactivity

Journal of clinical psychology, 2014-03, Vol.70 (3), p.209-223

2014

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Next-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening

The New England journal of medicine, 2024-03, Vol.390 (11), p.984-993

2024

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Highly complete long-read genomes reveal pangenomic variation underlying yeast phenotypic diversity

Genome research, 2023-05, Vol.33 (5), p.729-740

2023

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Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells

Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens

Editing the epigenome: technologies for programmable transcription and epigenetic modulation

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

Mammalian Synthetic Biology: Engineering Biological Systems

Synthetic transcription factors for cell fate reprogramming

Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells

CRISPR-based methods for high-throughput annotation of regulatory DNA

Results of the Two Incidence Screenings in the National Lung Screening Trial

Combinatorial Regulation of Endothelial Gene Expression by Ets and Forkhead Transcription Factors

Clinical Implications of Plasma-Based Genotyping With the Delivery of Personalized Therapy in Metastatic Non-Small Cell Lung Cancer

Prostate Cancer Screening in the Randomized Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial: Mortality Results after 13 Years of Follow-up

Transcriptomic analysis of AHR wildtype and Knock-out rat livers supports TCDD's role in AHR/ARNT-mediated circadian disruption and hepatotoxicity

Baseline Plasma Tumor Mutation Burden Predicts Response to Pembrolizumab-based Therapy in Patients with Metastatic Non-Small Cell Lung Cancer

Intensity‐modulated radiotherapy with planned Gamma Knife radiosurgery boost for head and neck cancer with extensive disease in proximity to critical structures

Characteristics of poisonings involving ketamine in the United States, 2019–2021

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Effect of screening on ovarian cancer mortality: the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Randomized Controlled Trial

Prospective validation of a risk score to predict pacemaker implantation after transcatheter aortic valve replacement

Characteristics of HIV seroconverters in the setting of universal test and treat: Results from the SEARCH trial in rural Uganda and Kenya

Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development

Perioperative Outcomes of Open versus Endovascular Repair for Ruptured Thoracoabdominal Aneurysms

Stressful Life Events and Depression Symptoms: The Effect of Childhood Emotional Abuse on Stress Reactivity

Next-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening

Highly complete long-read genomes reveal pangenomic variation underlying yeast phenotypic diversity

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