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Levels of 7alpha-hydroxycholesterol and/or 7alpha-hydroxy-4-cholest-3-one are the optimal biochemical markers for the evaluation of treatment of cerebrotendinous xanthomatosis

Journal of neurology, 2020-02, Vol.267 (2), p.572-573

2020

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Cerebrotendinous xanthomatosis: An inborn error in bile acid synthesis with defined mutations but still a challenge

Biochemical and biophysical research communications, 2010-05, Vol.396 (1), p.46-49

2010

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Genetic connections between neurological disorders and cholesterol metabolism

Journal of lipid research, 2010-09, Vol.51 (9), p.2489-2503

2010

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Cholesterol, oxysterol, triglyceride, and coenzyme Q homeostasis in ALS. Evidence against the hypothesis that elevated 27-hydroxycholesterol is a pathogenic factor

PloS one, 2014-11, Vol.9 (11), p.e113619-e113619

2014

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Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease

Brain (London, England : 1878), 2008-11, Vol.131 (11), p.2851-2859

2008

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Intestinal Cholesterol Absorption and Cardiovascular Risk

Journal of the American College of Cardiology, 2014-02, Vol.63 (7), p.695-696

2014

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CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice

Science advances, 2024-01, Vol.10 (4), p.eadj1354-eadj1354

2024

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Interactions of simvastatin and APOJ with amyloid processing in cerebrovascular endothelial cells

ATHEROSCLEROSIS, 2017-08, Vol.263, p.e85-e86

2017

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Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-07, Vol.877 (22), p.2081-2086

2009

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Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease

Neuroscience letters, 2009-10, Vol.462 (1), p.89-93

2009

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Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors

Biochemical and biophysical research communications, 2009-01, Vol.378 (4), p.689-694

2009

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On the mechanism of accumulation of cholestanol in the brain of mice with a disruption of sterol 27-hydroxylase

Journal of lipid research, 2010-09, Vol.51 (9), p.2722-2730

2010

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The desmosterolosis phenotype: spasticity, microcephaly and micrognathia with agenesis of corpus callosum and loss of white matter

European journal of human genetics : EJHG, 2011-09, Vol.19 (9), p.942-946

2011

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Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes

The Journal of biological chemistry, 2006-02, Vol.281 (7), p.3810-3820

2006

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Differential expression and function of ABCG1 and ABCG4 during development and aging[S]

Journal of lipid research, 2010-01, Vol.51 (1), p.169-181

2010

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Increased flux of the plant sterols campesterol and sitosterol across a disrupted blood brain barrier

Steroids, 2015-07, Vol.99 (Pt B), p.183-188

2015

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Activity-Regulated Cytoskeleton-Associated Protein in Rodent Brain is Down-Regulated by High Fat Diet in vivo and by 27-Hydroxycholesterol in vitro

Brain pathology (Zurich, Switzerland), 2009-01, Vol.19 (1), p.69-80

2009

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Primary Open-Angle Glaucoma: Association with Cholesterol 24S-Hydroxylase (CYP46A1) Gene Polymorphism and Plasma 24-Hydroxycholesterol Levels

Investigative ophthalmology & visual science, 2009-12, Vol.50 (12), p.5712-5717

2009

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Structural characterization of the gene encoding rat 25-hydroxyvitamin D3 24-hydroxylase

Biochemistry (Easton), 1993-01, Vol.32 (1), p.76-82

1993

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Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol

Arteriosclerosis, thrombosis, and vascular biology, 2007-10, Vol.27 (10), p.2191-2197

2007

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Detecting oxysterols in the human circulation

Nature immunology, 2011-07, Vol.12 (7), p.577; author reply 577-577

2011

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Diagnostic use of cerebral and extracerebral oxysterols

Clinical chemistry and laboratory medicine, 2004-02, Vol.42 (2), p.186-191

2004

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A functional polymorphism in the HMGCR promoter affects transcriptional activity but not the risk for Alzheimer disease in Swedish populations

Brain research, 2010-07, Vol.1344, p.185-191

2010

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Novel Mechanism for Oxidative Cleavage of Glycosidic Bonds: Evidence for an Oxygen Dependent Reaction

Journal of organic chemistry, 1994-12, Vol.59 (26), p.8251-8255

1994

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Role of Oxysterols in the Regulation of Cholesterol Homeostasis: A Critical Evaluation

Accounts of chemical research, 1995-06, Vol.28 (6), p.241-249

1995

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Levels of 7alpha-hydroxycholesterol and/or 7alpha-hydroxy-4-cholest-3-one are the optimal biochemical markers for the evaluation of treatment of cerebrotendinous xanthomatosis

Cerebrotendinous xanthomatosis: An inborn error in bile acid synthesis with defined mutations but still a challenge

Genetic connections between neurological disorders and cholesterol metabolism

Cholesterol, oxysterol, triglyceride, and coenzyme Q homeostasis in ALS. Evidence against the hypothesis that elevated 27-hydroxycholesterol is a pathogenic factor

Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease

Intestinal Cholesterol Absorption and Cardiovascular Risk

CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice

Interactions of simvastatin and APOJ with amyloid processing in cerebrovascular endothelial cells

Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells

Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease

Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors

On the mechanism of accumulation of cholestanol in the brain of mice with a disruption of sterol 27-hydroxylase

The desmosterolosis phenotype: spasticity, microcephaly and micrognathia with agenesis of corpus callosum and loss of white matter

Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes

Differential expression and function of ABCG1 and ABCG4 during development and aging[S]

Increased flux of the plant sterols campesterol and sitosterol across a disrupted blood brain barrier

Activity-Regulated Cytoskeleton-Associated Protein in Rodent Brain is Down-Regulated by High Fat Diet in vivo and by 27-Hydroxycholesterol in vitro

Primary Open-Angle Glaucoma: Association with Cholesterol 24S-Hydroxylase (CYP46A1) Gene Polymorphism and Plasma 24-Hydroxycholesterol Levels

Structural characterization of the gene encoding rat 25-hydroxyvitamin D3 24-hydroxylase

Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol

Detecting oxysterols in the human circulation

Diagnostic use of cerebral and extracerebral oxysterols

A functional polymorphism in the HMGCR promoter affects transcriptional activity but not the risk for Alzheimer disease in Swedish populations

Novel Mechanism for Oxidative Cleavage of Glycosidic Bonds: Evidence for an Oxygen Dependent Reaction

Role of Oxysterols in the Regulation of Cholesterol Homeostasis: A Critical Evaluation

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