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Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia： Yin and Yang

Cancer biology & medicine, 2016-06, Vol.13 (2), p.248-259

2016

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SMAC mimetics as potential cancer therapeutics in myeloid malignancies

British journal of haematology, 2019-04, Vol.185 (2), p.219-231

2019

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Menin inhibition decreases Bcl-2 and synergizes with venetoclax in NPM1/FLT3-mutated AML

Blood, 2021-10, Vol.138 (17), p.1637-1641

2021

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EXABS-147-AML How Do We Overcome Resistance to Venetoclax

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22 Suppl 2, p.S55-S57

2022

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Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells

Science translational medicine, 2016-09, Vol.8 (355), p.355ra117

2016

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An ARC-Regulated IL1β/Cox-2/PGE2/β-Catenin/ARC Circuit Controls Leukemia-Microenvironment Interactions and Confers Drug Resistance in AML

Cancer research (Chicago, Ill.), 2019-03, Vol.79 (6), p.1165-1177

2019

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ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia

Nature communications, 2023-09, Vol.14 (1), p.5709-5709, Article 5709

2023

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Molecular Mechanisms of Ferroptosis and Updates of Ferroptosis Studies in Cancers and Leukemia

Cells (Basel, Switzerland), 2023-04, Vol.12 (8), p.1128

2023

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Bcl-2 inhibition combined with PPARα activation synergistically targets leukemic stem cell-like cells in acute myeloid leukemia

Cell death & disease, 2023-08, Vol.14 (8), p.573-573, Article 573

2023

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Beyond BCL-2 Inhibition in Acute Myloid Leukemia: Other Approaches to Leverage the Apoptotic Pathway

Clinical lymphoma, myeloma and leukemia, 2022-09, Vol.22 (9), p.652-658

2022

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Combined inhibition of MDM2 and BCR-ABL1 tyrosine kinase targets chronic myeloid leukemia stem/progenitor cells in a murine model

Haematologica (Roma), 2020-05, Vol.105 (5), p.1274

2020

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A novel HDAC inhibitor chidamide combined with imatinib synergistically targets tyrosine kinase inhibitor resistant chronic myeloid leukemia cells

Biomedicine & pharmacotherapy, 2020-09, Vol.129, p.110390, Article 110390

2020

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AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3 -ITD acute myeloid leukemia

Haematologica (Roma), 2022-06, Vol.107 (6), p.1311

2022

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Disruption of Wnt/β-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3 -Mutant Acute Myeloid Leukemia

Clinical cancer research, 2018-05, Vol.24 (10), p.2417-2429

2018

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Combinatorial Inhibition of Focal Adhesion Kinase and BCL-2 Enhances Antileukemia Activity of Venetoclax in Acute Myeloid Leukemia

Molecular cancer therapeutics, 2020-08, Vol.19 (8), p.1636-1648

2020

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miR-150 exerts antileukemia activity in vitro and in vivo through regulating genes in multiple pathways

Cell death & disease, 2016-09, Vol.7 (9), p.e2371-e2371

2016

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Research on red tide short-time prediction using GRU network model based on multi-feature Factors——A case in Xiamen sea area

Marine environmental research, 2022-12, Vol.182, p.105727-105727, Article 105727

2022

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Impact of FLT3-ITD allele ratio and ITD length on therapeutic outcome in cytogenetically normal AML patients without NPM1 mutation

Bone marrow transplantation (Basingstoke), 2020-04, Vol.55 (4), p.740-748

2020

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Inhibition of EZH2 by chidamide exerts antileukemia activity and increases chemosensitivity through Smo/Gli-1 pathway in acute myeloid leukemia

Journal of translational medicine, 2021-03, Vol.19 (1), p.117-117, Article 117

2021

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Survivin is highly expressed in CD34+38− leukemic stem/progenitor cells and predicts poor clinical outcomes in AML

Blood, 2012-07, Vol.120 (1), p.173-180

2012

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Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia

Leukemia, 2024-04, Vol.38 (4), p.729-740

2024

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Application of machine learning methods in clinical trials for precision medicine

JAMIA open, 2022-04, Vol.5 (1), p.ooab107

2022

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Loss of expression of both miR-15/16 loci in CML transition to blast crisis

Proceedings of the National Academy of Sciences - PNAS, 2021-03, Vol.118 (11), p.1

2021

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Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms

Oncotarget, 2014-10, Vol.5 (19), p.9118-9132

2014

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Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia： Yin and Yang

SMAC mimetics as potential cancer therapeutics in myeloid malignancies

Menin inhibition decreases Bcl-2 and synergizes with venetoclax in NPM1/FLT3-mutated AML

EXABS-147-AML How Do We Overcome Resistance to Venetoclax

Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells

An ARC-Regulated IL1β/Cox-2/PGE2/β-Catenin/ARC Circuit Controls Leukemia-Microenvironment Interactions and Confers Drug Resistance in AML

ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia

Molecular Mechanisms of Ferroptosis and Updates of Ferroptosis Studies in Cancers and Leukemia

Bcl-2 inhibition combined with PPARα activation synergistically targets leukemic stem cell-like cells in acute myeloid leukemia

Beyond BCL-2 Inhibition in Acute Myloid Leukemia: Other Approaches to Leverage the Apoptotic Pathway

Combined inhibition of MDM2 and BCR-ABL1 tyrosine kinase targets chronic myeloid leukemia stem/progenitor cells in a murine model

A novel HDAC inhibitor chidamide combined with imatinib synergistically targets tyrosine kinase inhibitor resistant chronic myeloid leukemia cells

AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3 -ITD acute myeloid leukemia

Disruption of Wnt/β-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3 -Mutant Acute Myeloid Leukemia

Combinatorial Inhibition of Focal Adhesion Kinase and BCL-2 Enhances Antileukemia Activity of Venetoclax in Acute Myeloid Leukemia

miR-150 exerts antileukemia activity in vitro and in vivo through regulating genes in multiple pathways

Research on red tide short-time prediction using GRU network model based on multi-feature Factors——A case in Xiamen sea area

Impact of FLT3-ITD allele ratio and ITD length on therapeutic outcome in cytogenetically normal AML patients without NPM1 mutation

Inhibition of EZH2 by chidamide exerts antileukemia activity and increases chemosensitivity through Smo/Gli-1 pathway in acute myeloid leukemia

Survivin is highly expressed in CD34+38− leukemic stem/progenitor cells and predicts poor clinical outcomes in AML

Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia

Combination of dasatinib and venetoclax in newly diagnosed chronic phase chronic myeloid leukemia

Application of machine learning methods in clinical trials for precision medicine

Loss of expression of both miR-15/16 loci in CML transition to blast crisis

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms

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