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Learning with reinforcement prediction errors in a model of the Drosophila mushroom body

Nature communications, 2021-05, Vol.12 (1), p.2569-2569, Article 2569

2021

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Oxalyl Boronates Enable Modular Synthesis of Bioactive Imidazoles

Angewandte Chemie International Edition, 2017-05, Vol.56 (22), p.6264-6267

International ed. in English, 2017

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LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor

Angewandte Chemie (International ed.), 2015-05, Vol.54 (21), p.6217-6221

International ed. in English, 2015

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SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK)

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2830-2836

2019

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Identification and Optimization of 4‐Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase

ChemMedChem, 2018-01, Vol.13 (1), p.48-66

2018

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An Improved Small-Molecule Inhibitor of FtsZ with Superior In Vitro Potency, Drug-Like Properties, and In Vivo Efficacy

Antimicrobial Agents and Chemotherapy, 2013-01, Vol.57 (1), p.317-325

2013

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Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK)

Molecules (Basel, Switzerland), 2019-11, Vol.24 (22), p.4016

2019

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Design and Analysis of the 4‐Anilinoquin(az)oline Kinase Inhibition Profiles of GAK/SLK/STK10 Using Quantitative Structure‐Activity Relationships

ChemMedChem, 2020-01, Vol.15 (1), p.26-49

2020

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Design, synthesis and structure-activity relationships of substituted oxazole-benzamide antibacterial inhibitors of FtsZ

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (1), p.353-359

2014

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Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety

Organic & biomolecular chemistry, 2017, Vol.15 (40), p.8655-8660

2017

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Biological Evaluation of Benzothiazole Ethyl Urea Inhibitors of Bacterial Type II Topoisomerases

Antimicrobial Agents and Chemotherapy, 2013-12, Vol.57 (12), p.5977-5986

2013

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Refinement and Pattern Formation in Neural Circuits by the Interaction of Traveling Waves with Spike-Timing Dependent Plasticity

PLoS computational biology, 2015-08, Vol.11 (8), p.e1004422-e1004422

2015

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Novel Inhibitors of Bacterial Cytokinesis Identified by a Cell-based Antibiotic Screening Assay

The Journal of biological chemistry, 2005-12, Vol.280 (48), p.39709-39715

2005

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Modular Synthesis of Di- and Trisubstituted Imidazoles from Ketones and Aldehydes: A Route to Kinase Inhibitors

Journal of organic chemistry, 2019-11, Vol.84 (21), p.14187-14201

2019

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Imidazo[1,2-b]pyridazines as inhibitors of DYRK kinases

European journal of medicinal chemistry, 2024-04, Vol.269, p.116292-116292, Article 116292

2024

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Inhibitor of FtsZ with Potent and Selective Anti-Staphylococcal Activity

Science (American Association for the Advancement of Science), 2008-09, Vol.321 (5896), p.1673-1675

2008

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8‑Substituted Pyrido[3,4‑d]pyrimidin-4(3H)‑one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

Journal of medicinal chemistry, 2016-02, Vol.59 (4), p.1388-1409

2016

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Identification and Optimization of 4-Anilinoquinolines as Inhibitors of CyclinG Associated Kinase

ChemMedChem, 2018-01, Vol.13 (1), p.48

2018

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Oxalyl Boronates Enable Modular Synthesis of Bioactive Imidazoles

Angewandte Chemie, 2017-05, Vol.129 (22), p.6360-6363

2017

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Targeting the Water Network in Cyclin G‐Associated Kinase (GAK) with 4‐Anilino‐quin(az)oline Inhibitors

ChemMedChem, 2020-07, Vol.15 (13), p.1200-1215

2020

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Creating an Antibacterial with in Vivo Efficacy: Synthesis and Characterization of Potent Inhibitors of the Bacterial Cell Division Protein FtsZ with Improved Pharmaceutical Properties

Journal of medicinal chemistry, 2010-05, Vol.53 (10), p.3927-3936

2010

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Frequent multiple hepatitis C virus infections among injection drug users in a prison setting

Hepatology (Baltimore, Md.), 2010-11, Vol.52 (5), p.1564-1572

2010

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C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays

European journal of medicinal chemistry, 2019-09, Vol.177, p.316-337

2019

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Learning with reinforcement prediction errors in a model of the Drosophila mushroom body

Oxalyl Boronates Enable Modular Synthesis of Bioactive Imidazoles

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor

SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK)

Identification and Optimization of 4‐Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase

An Improved Small-Molecule Inhibitor of FtsZ with Superior In Vitro Potency, Drug-Like Properties, and In Vivo Efficacy

Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK)

Design and Analysis of the 4‐Anilinoquin(az)oline Kinase Inhibition Profiles of GAK/SLK/STK10 Using Quantitative Structure‐Activity Relationships

Design, synthesis and structure-activity relationships of substituted oxazole-benzamide antibacterial inhibitors of FtsZ

Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety

Biological Evaluation of Benzothiazole Ethyl Urea Inhibitors of Bacterial Type II Topoisomerases

Refinement and Pattern Formation in Neural Circuits by the Interaction of Traveling Waves with Spike-Timing Dependent Plasticity

Novel Inhibitors of Bacterial Cytokinesis Identified by a Cell-based Antibiotic Screening Assay

Modular Synthesis of Di- and Trisubstituted Imidazoles from Ketones and Aldehydes: A Route to Kinase Inhibitors

Imidazo[1,2-b]pyridazines as inhibitors of DYRK kinases

Inhibitor of FtsZ with Potent and Selective Anti-Staphylococcal Activity

8‑Substituted Pyrido[3,4‑d]pyrimidin-4(3H)‑one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop

Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action

Identification and Optimization of 4-Anilinoquinolines as Inhibitors of CyclinG Associated Kinase

Oxalyl Boronates Enable Modular Synthesis of Bioactive Imidazoles

Targeting the Water Network in Cyclin G‐Associated Kinase (GAK) with 4‐Anilino‐quin(az)oline Inhibitors

Creating an Antibacterial with in Vivo Efficacy: Synthesis and Characterization of Potent Inhibitors of the Bacterial Cell Division Protein FtsZ with Improved Pharmaceutical Properties

Frequent multiple hepatitis C virus infections among injection drug users in a prison setting

C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays

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