UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 55

Sortiert nach

LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network

Human molecular genetics, 2018-01, Vol.27 (2), p.385-395

2018

Link zum Volltext

Verfügbarkeit prüfen

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

Human molecular genetics, 2011-01, Vol.20 (1), p.40-50

2011

Link zum Volltext

Verfügbarkeit prüfen

Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC

Cellular and molecular life sciences : CMLS, 2020-09, Vol.77 (18), p.3611-3626

2020

Link zum Volltext

Verfügbarkeit prüfen

Lysosomal positioning regulates Rab10 phosphorylation at LRRK2 + lysosomes

Proceedings of the National Academy of Sciences - PNAS, 2022-10, Vol.119 (43), p.1-e2205492119

2022

Link zum Volltext

Verfügbarkeit prüfen

Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice

Human molecular genetics, 2018-09, Vol.27 (18), p.3257-3271

2018

Link zum Volltext

Verfügbarkeit prüfen

LRRK2 mediates tubulation and vesicle sorting from lysosomes

Science advances, 2020-11, Vol.6 (46)

2020

Link zum Volltext

Verfügbarkeit prüfen

Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (5), p.1499-1504

2008

Link zum Volltext

Verfügbarkeit prüfen

The R1441C mutation of LRRK2 disrupts GTP hydrolysis

Biochemical and biophysical research communications, 2007-06, Vol.357 (3), p.668-671

2007

Link zum Volltext

Verfügbarkeit prüfen

Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins

Proteomics (Weinheim), 2018-05, Vol.18 (10), p.e1700444-n/a

2018

Link zum Volltext

Verfügbarkeit prüfen

The Parkinson’s Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network

Cell reports (Cambridge), 2020-05, Vol.31 (5), p.107614-107614, Article 107614

2020

Link zum Volltext

Verfügbarkeit prüfen

The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) Is a Dimer That Undergoes Intramolecular Autophosphorylation

The Journal of biological chemistry, 2008-06, Vol.283 (24), p.16906-16914

2008

Link zum Volltext

Verfügbarkeit prüfen

Correction to: Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC

Cellular and molecular life sciences : CMLS, 2020-09, Vol.77 (18), p.3691-3692

2020

Link zum Volltext

Verfügbarkeit prüfen

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

Neurobiology of disease, 2006-08, Vol.23 (2), p.329-341

2006

Link zum Volltext

Verfügbarkeit prüfen

Mutations in PTEN-Induced Putative Kinase 1 Associated with Recessive Parkinsonism Have Differential Effects on Protein Stability

Proceedings of the National Academy of Sciences - PNAS, 2005-04, Vol.102 (16), p.5703-5708

2005

Link zum Volltext

Verfügbarkeit prüfen

Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers

PloS one, 2012-08, Vol.7 (8), p.e43472-e43472

2012

Link zum Volltext

Verfügbarkeit prüfen

Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1

PloS one, 2009-05, Vol.4 (5), p.e5701

2009

Link zum Volltext

Verfügbarkeit prüfen

Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia

PLoS biology, 2022-05, Vol.20 (5), p.e3001621-e3001621

2022

Link zum Volltext

Verfügbarkeit prüfen

LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding

PloS one, 2011-08, Vol.6 (8), p.e23207

2011

Link zum Volltext

Verfügbarkeit prüfen

Differential protein–protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways

Journal of neurochemistry, 2014-10, Vol.131 (2), p.239-250

2014

Link zum Volltext

Verfügbarkeit prüfen

Generation of iPSC line from a Parkinson patient with PARK7 mutation and CRISPR-edited Gibco human episomal iPSC line to mimic PARK7 mutation

Stem cell research, 2021-08, Vol.55, p.102506-102506, Article 102506

2021

Link zum Volltext

Verfügbarkeit prüfen

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (29), p.10244-10249

2008

Link zum Volltext

Verfügbarkeit prüfen

Hexokinases link DJ-1 to the PINK1/parkin pathway

Molecular neurodegeneration, 2017-09, Vol.12 (1), p.70-70, Article 70

2017

Link zum Volltext

Verfügbarkeit prüfen

Arsenite Stress Down-regulates Phosphorylation and 14-3-3 Binding of Leucine-rich Repeat Kinase 2 (LRRK2), Promoting Self-association and Cellular Redistribution

The Journal of biological chemistry, 2014-08, Vol.289 (31), p.21386-21400

2014

Link zum Volltext

Verfügbarkeit prüfen

Age-associated changes in gene expression in human brain and isolated neurons

Neurobiology of aging, 2013-04, Vol.34 (4), p.1199-1209

2013

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 55

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(53)
Mit Volltextzugriff
(53)

Publikationsform

Sprache

Erscheinungsjahr

n.n

Thema

Science & Technology
(38)
Humans
(32)
Life Sciences & Biomedicine
(28)
Mutation
(19)
Parkinson's Disease
(19)
Biochemistry & Molecular Biology
(18)
Animals
(16)
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
(14)
Neurosciences
(13)
Phosphorylation
(13)
Parkinson Disease - Genetics
(12)
Mice
(11)
Parkinsons Disease
(11)
Proteins
(11)
Multidisciplinary Sciences
(10)
Neurosciences & Neurology
(10)
Parkinson Disease - Metabolism
(10)
Science & Technology - Other Topics
(10)
Kinases
(9)
Molecular Biology
(9)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network

Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC

Lysosomal positioning regulates Rab10 phosphorylation at LRRK2 + lysosomes

Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice

LRRK2 mediates tubulation and vesicle sorting from lysosomes

Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase

The R1441C mutation of LRRK2 disrupts GTP hydrolysis

Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins

The Parkinson’s Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network

The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) Is a Dimer That Undergoes Intramolecular Autophosphorylation

Correction to: Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

Mutations in PTEN-Induced Putative Kinase 1 Associated with Recessive Parkinsonism Have Differential Effects on Protein Stability

Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers

Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1

Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia

LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding

Differential protein–protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways

Generation of iPSC line from a Parkinson patient with PARK7 mutation and CRISPR-edited Gibco human episomal iPSC line to mimic PARK7 mutation

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

Hexokinases link DJ-1 to the PINK1/parkin pathway

Arsenite Stress Down-regulates Phosphorylation and 14-3-3 Binding of Leucine-rich Repeat Kinase 2 (LRRK2), Promoting Self-association and Cellular Redistribution

Age-associated changes in gene expression in human brain and isolated neurons

Suchergebnisse filtern