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CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection

Cell reports (Cambridge), 2021-09, Vol.36 (11), p.109696-109696, Article 109696

2021

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Evasion of innate immunity by Mycobacterium tuberculosis : is death an exit strategy?

Nature reviews. Microbiology, 2010-09, Vol.8 (9), p.668-674

2010

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Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

Cell, 2013-12, Vol.155 (6), p.1296-1308

2013

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In search of a new paradigm for protective immunity to TB

Nature reviews. Microbiology, 2014-04, Vol.12 (4), p.289-299

2014

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TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection

PLoS pathogens, 2016-03, Vol.12 (3), p.e1005490-e1005490

2016

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Heterogeneity in lung macrophage control of Mycobacterium tuberculosis is modulated by T cells

Nature communications, 2024-07, Vol.15 (1), p.5710-12, Article 5710

2024

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Efferocytosis Is an Innate Antibacterial Mechanism

Cell host & microbe, 2012-09, Vol.12 (3), p.289-300

2012

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Emerging Tim-3 functions in antimicrobial and tumor immunity

Trends in immunology, 2011-08, Vol.32 (8), p.345-349

2011

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iNKT cell production of GM-CSF controls Mycobacterium tuberculosis

PLoS pathogens, 2014-01, Vol.10 (1), p.e1003805-e1003805

2014

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Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis

Nature immunology, 2010-08, Vol.11 (8), p.751-758

2010

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Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages

PLoS pathogens, 2018-05, Vol.14 (5), p.e1007060-e1007060

2018

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Use of the Human Granulysin Transgenic Mice To Evaluate the Role of Granulysin Expression by CD8 T Cells in Immunity To Mycobacterium tuberculosis

mBio, 2022-12, Vol.13 (6), p.e0302022-e0302022

2022

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Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis

The Journal of clinical investigation, 2023-07, Vol.133 (13), p.1-16

2023

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A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response

PLoS pathogens, 2020-10, Vol.16 (10), p.e1009000-e1009000

2020

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Key advances in vaccine development for tuberculosis—success and challenges

npj vaccines, 2023-10, Vol.8 (1), p.158-10, Article 158

2023

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Tim3 binding to galectin-9 stimulates antimicrobial immunity

The Journal of experimental medicine, 2010-10, Vol.207 (11), p.2343-2354

2010

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Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype

mBio, 2016-09, Vol.7 (5)

2016

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A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis

PLoS pathogens, 2016-01, Vol.12 (1), p.e1005380-e1005380

2016

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Innate invariant NKT cells recognize Mycobacterium tuberculosis-infected macrophages, produce interferon-gamma, and kill intracellular bacteria

PLoS pathogens, 2008-12, Vol.4 (12), p.e1000239-e1000239

2008

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CD11cHi monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis

PLoS pathogens, 2020-06, Vol.16 (6), p.e1008621-e1008621

2020

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Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection

The Journal of experimental medicine, 2011-10, Vol.208 (11), p.2251-2262

2011

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Apoptosis inhibition by intracellular bacteria and its consequence on host immunity

Current opinion in immunology, 2019-10, Vol.60, p.103-110

2019

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Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (5), p.1827-1832

2013

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Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells

eLife, 2021-11, Vol.10

2021

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Tuberculosis Triggers a Tissue-Dependent Program of Differentiation and Acquisition of Effector Functions by Circulating Monocytes

The Journal of immunology (1950), 2008-11, Vol.181 (9), p.6349-6360

2008

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CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection

Evasion of innate immunity by Mycobacterium tuberculosis : is death an exit strategy?

Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

In search of a new paradigm for protective immunity to TB

TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection

Heterogeneity in lung macrophage control of Mycobacterium tuberculosis is modulated by T cells

Efferocytosis Is an Innate Antibacterial Mechanism

Emerging Tim-3 functions in antimicrobial and tumor immunity

iNKT cell production of GM-CSF controls Mycobacterium tuberculosis

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis

Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages

Use of the Human Granulysin Transgenic Mice To Evaluate the Role of Granulysin Expression by CD8 T Cells in Immunity To Mycobacterium tuberculosis

Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis

A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response

Key advances in vaccine development for tuberculosis—success and challenges

Tim3 binding to galectin-9 stimulates antimicrobial immunity

Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype

A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis

Innate invariant NKT cells recognize Mycobacterium tuberculosis-infected macrophages, produce interferon-gamma, and kill intracellular bacteria

CD11cHi monocyte-derived macrophages are a major cellular compartment infected by Mycobacterium tuberculosis

Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection

Apoptosis inhibition by intracellular bacteria and its consequence on host immunity

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs

Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells

Tuberculosis Triggers a Tissue-Dependent Program of Differentiation and Acquisition of Effector Functions by Circulating Monocytes

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