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Mutations in hereditary phosphoglucomutase 1 deficiency map to key regions of enzyme structure and function

Journal of inherited metabolic disease, 2015-03, Vol.38 (2), p.243-256

Beamer, Lesa J.

2015

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High‐resolution modeling of coastal freshwater discharge and glacier mass balance in the Gulf of Alaska watershed

Water resources research, 2016-05, Vol.52 (5), p.3888-3909

2016

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Structural insights into binding of polyglutamylated tetrahydrofolate by serine hydroxymethyltransferase 8 from soybean

Frontiers in plant science, 2024-08, Vol.15, p.1451839

2024

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Hydrologic impacts of changes in climate and glacier extent in the Gulf of Alaska watershed

Water resources research, 2017-09, Vol.53 (9), p.7502-7520

2017

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Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (10), p.3039-3043

2013

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Sequence-structure relationships, expression profiles, and disease-associated mutations in the paralogs of phosphoglucomutase 1

PloS one, 2017-08, Vol.12 (8), p.e0183563-e0183563

2017

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Crystal Structure of the Kelch Domain of Human Keap1

The Journal of biological chemistry, 2004-12, Vol.279 (52), p.54750-54758

2004

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Enzyme dysfunction at atomic resolution: Disease-associated variants of human phosphoglucomutase-1

Biochimie, 2021-04, Vol.183, p.44-48

Beamer, Lesa J.

2021

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Optimization of fluorescently labeled Nrf2 peptide probes and the development of a fluorescence polarization assay for the discovery of inhibitors of Keap1-Nrf2 interaction

Journal of biomolecular screening, 2012-04, Vol.17 (4), p.435-447

2012

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Phosphorylation in the Catalytic Cleft Stabilizes and Attracts Domains of a Phosphohexomutase

Biophysical journal, 2015-01, Vol.108 (2), p.325-337

2015

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Crystal Structure of Bacillus anthracis Phosphoglucosamine Mutase, an Enzyme in the Peptidoglycan Biosynthetic Pathway

Journal of Bacteriology, 2011-08, Vol.193 (16), p.4081-4087

2011

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A coevolutionary residue network at the site of a functionally important conformational change in a phosphohexomutase enzyme family

PloS one, 2012-06, Vol.7 (6), p.e38114

2012

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Crystal Structure of Human BPI and Two Bound Phospholipids at 2.4 Angstrom Resolution

Science (American Association for the Advancement of Science), 1997-06, Vol.276 (5320), p.1861-1864

1997

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Use of ultrasound intraoperatively to locate extraoral implants

British journal of oral & maxillofacial surgery, 2019-04, Vol.57 (3), p.291-292

2019

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Multiple Ligand-Bound States of a Phosphohexomutase Revealed by Principal Component Analysis of NMR Peak Shifts

Scientific reports, 2017-07, Vol.7 (1), p.5343-11, Article 5343

2017

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A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics

Structure (London), 2018-10, Vol.26 (10), p.1337-1345.e3

2018

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Spatial and temporal variability of freshwater discharge into the Gulf of Alaska

Journal of geophysical research. Oceans, 2015-02, Vol.120 (2), p.634-646

2015

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Data on the phosphorylation state of the catalytic serine of enzymes in the α-D-phosphohexomutase superfamily

Data in brief, 2017-02, Vol.10 (C), p.398-405

2017

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Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

The EMBO journal, 2006-08, Vol.25 (15), p.3605-3617

2006

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Structural and functional analysis of two SHMT8 variants associated with soybean cyst nematode resistance

The FEBS journal, 2024-01, Vol.291 (2), p.323-337

2024

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Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono‑, Di‑, and Trifluorinated d‑Gluco-heptuloses by Glucokinase: Tunable Phosphoglucomutase Inhibition

ACS omega, 2019-04, Vol.4 (4), p.7029-7037

2019

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Structural and dynamical description of the enzymatic reaction of a phosphohexomutase

Structural dynamics (Melville, N.Y.), 2019-03, Vol.6 (2), p.024703-024703

2019

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Compromised Catalysis and Potential Folding Defects in in Vitro Studies of Missense Mutants Associated with Hereditary Phosphoglucomutase 1 Deficiency

The Journal of biological chemistry, 2014-11, Vol.289 (46), p.32010-32019

2014

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Impaired folate binding of serine hydroxymethyltransferase 8 from soybean underlies resistance to the soybean cyst nematode

The Journal of biological chemistry, 2020-03, Vol.295 (11), p.3708-3718

2020

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Mutations in hereditary phosphoglucomutase 1 deficiency map to key regions of enzyme structure and function

High‐resolution modeling of coastal freshwater discharge and glacier mass balance in the Gulf of Alaska watershed

Structural insights into binding of polyglutamylated tetrahydrofolate by serine hydroxymethyltransferase 8 from soybean

Hydrologic impacts of changes in climate and glacier extent in the Gulf of Alaska watershed

Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction

Sequence-structure relationships, expression profiles, and disease-associated mutations in the paralogs of phosphoglucomutase 1

Crystal Structure of the Kelch Domain of Human Keap1

Enzyme dysfunction at atomic resolution: Disease-associated variants of human phosphoglucomutase-1

Optimization of fluorescently labeled Nrf2 peptide probes and the development of a fluorescence polarization assay for the discovery of inhibitors of Keap1-Nrf2 interaction

Phosphorylation in the Catalytic Cleft Stabilizes and Attracts Domains of a Phosphohexomutase

Crystal Structure of Bacillus anthracis Phosphoglucosamine Mutase, an Enzyme in the Peptidoglycan Biosynthetic Pathway

Defining the Phenotype and Assessing Severity in Phosphoglucomutase-1 Deficiency

A coevolutionary residue network at the site of a functionally important conformational change in a phosphohexomutase enzyme family

Crystal Structure of Human BPI and Two Bound Phospholipids at 2.4 Angstrom Resolution

Use of ultrasound intraoperatively to locate extraoral implants

Multiple Ligand-Bound States of a Phosphohexomutase Revealed by Principal Component Analysis of NMR Peak Shifts

A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics

Spatial and temporal variability of freshwater discharge into the Gulf of Alaska

Data on the phosphorylation state of the catalytic serine of enzymes in the α-D-phosphohexomutase superfamily

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

Structural and functional analysis of two SHMT8 variants associated with soybean cyst nematode resistance

Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono‑, Di‑, and Trifluorinated d‑Gluco-heptuloses by Glucokinase: Tunable Phosphoglucomutase Inhibition

Structural and dynamical description of the enzymatic reaction of a phosphohexomutase

Compromised Catalysis and Potential Folding Defects in in Vitro Studies of Missense Mutants Associated with Hereditary Phosphoglucomutase 1 Deficiency

Impaired folate binding of serine hydroxymethyltransferase 8 from soybean underlies resistance to the soybean cyst nematode

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