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Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques

Circulation research, 2009-07, Vol.105 (2), p.128-137

2009

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P2Y12 receptor blockers are anti-inflammatory drugs inhibiting both circulating monocytes and macrophages including THP-1 cells

Scientific reports, 2021-08, Vol.11 (1), p.17459-17459, Article 17459

2021

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An engineered T-cell engager with selectivity for high mesothelin-expressing cells and activity in the presence of soluble mesothelin

Oncoimmunology, 2023-12, Vol.12 (1), p.2233401-2233401

2023

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Amyloid Plaques Dissociate Pentameric to Monomeric C-Reactive Protein: A Novel Pathomechanism Driving Cortical Inflammation in Alzheimer's Disease?

Brain pathology (Zurich, Switzerland), 2012-05, Vol.22 (3), p.337-346

2012

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Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target

Arteriosclerosis, thrombosis, and vascular biology, 2011-07, Vol.31 (7), p.1607

2011

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1389 An assessment of ROR1 expression across tumor tissue and the investigation of a ROR1-targeted T cell engager as a therapeutic strategy to target ROR1 positive tumors

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1544-A1544

2023

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Subtractive single-chain antibody (scFv) phage-display: tailoring phage-display for high specificity against function-specific conformations of cell membrane molecules

Nature protocols, 2007-11, Vol.2 (12), p.3063-3073

2007

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CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies

PloS one, 2012-03, Vol.7 (3), p.e33026-e33026

2012

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GPVI and GPIbα mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors

PloS one, 2011-04, Vol.6 (4), p.e19190

2011

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844 A trispecific ROR1 x CD3 T cell engager mediates in vitro tumor cell killing and in vivo tumor eradication

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A885-A885

2021

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Selenium supplementation induces metalloproteinase-dependent L-selectin shedding from monocytes

Journal of leukocyte biology, 2008-06, Vol.83 (6), p.1388-1395

2008

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Microparticles: major transport vehicles for distinct microRNAs in circulation

Cardiovascular research, 2012-03, Vol.93 (4), p.633-644

2012

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LIM kinase 2 (LIMK2) may play an essential role in platelet function

Experimental cell research, 2020-03, Vol.388 (1), p.111822-111822, Article 111822

2020

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Reversibility versus persistence of GPIIb/IIIa blocker-induced conformational change of GPIIb/IIIa (alphaIIbbeta3, CD41/CD61)

The Journal of pharmacology and experimental therapeutics, 2004-03, Vol.308 (3), p.1002

2004

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Evaluation of platelet activation in patients supported by the Jarvik 2000∗ high–rotational speed impeller ventricular assist device

The Journal of thoracic and cardiovascular surgery, 2009-03, Vol.137 (3), p.736-741

2009

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Pharmacological inhibition of LIM kinase pathway impairs platelets functionality and facilitates thrombolysis

Experimental cell research, 2019-09, Vol.382 (2), p.111458-111458, Article 111458

2019

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Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction

Cardiovascular research, 2012-10, Vol.96 (1), p.64-72

2012

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Abstract 525: Novel DARPin multi-specific T-cell engager with an improved therapeutic window to overcome dose limiting toxicities in AML therapies

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.525-525

2021

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Lysophosphatidylcholine is a Major Component of Platelet Microvesicles Promoting Platelet Activation and Reporting Atherosclerotic Plaque Instability

Thrombosis and haemostasis, 2019-08, Vol.119 (8), p.1295

2019

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HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi

Thrombosis and haemostasis, 2015-11, Vol.114 (5), p.994

2015

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Abstract 690: Application of the DARPin® technology for specific targeting of tumor-associated MHC class I:peptide complexes

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.690-690

2020

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Fibrin-targeted direct factor Xa inhibition: construction and characterization of a recombinant factor Xa inhibitor composed of an anti-fibrin single-chain antibody and tick anticoagulant peptide

Thrombosis and haemostasis, 2004-07, Vol.92 (1), p.47

2004

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CD40 ligand mediates inflammation independently of CD40 by interaction with mac-1

Circulation (New York, N.Y.), 2007-03, Vol.115 (12), p.1571-1580

2007

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A DARPin targeting activated Mac-1 is a novel diagnostic tool and potential anti-inflammatory agent in myocarditis, sepsis and myocardial infarction

Basic research in cardiology, 2021-12, Vol.116 (1), p.17, Article 17

2021

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Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques

P2Y12 receptor blockers are anti-inflammatory drugs inhibiting both circulating monocytes and macrophages including THP-1 cells

An engineered T-cell engager with selectivity for high mesothelin-expressing cells and activity in the presence of soluble mesothelin

Amyloid Plaques Dissociate Pentameric to Monomeric C-Reactive Protein: A Novel Pathomechanism Driving Cortical Inflammation in Alzheimer's Disease?

Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target

1389 An assessment of ROR1 expression across tumor tissue and the investigation of a ROR1-targeted T cell engager as a therapeutic strategy to target ROR1 positive tumors

Subtractive single-chain antibody (scFv) phage-display: tailoring phage-display for high specificity against function-specific conformations of cell membrane molecules

CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies

GPVI and GPIbα mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors

844 A trispecific ROR1 x CD3 T cell engager mediates in vitro tumor cell killing and in vivo tumor eradication

Selenium supplementation induces metalloproteinase-dependent L-selectin shedding from monocytes

Microparticles: major transport vehicles for distinct microRNAs in circulation

LIM kinase 2 (LIMK2) may play an essential role in platelet function

Correction: CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies

Reversibility versus persistence of GPIIb/IIIa blocker-induced conformational change of GPIIb/IIIa (alphaIIbbeta3, CD41/CD61)

Evaluation of platelet activation in patients supported by the Jarvik 2000∗ high–rotational speed impeller ventricular assist device

Pharmacological inhibition of LIM kinase pathway impairs platelets functionality and facilitates thrombolysis

Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction

Abstract 525: Novel DARPin multi-specific T-cell engager with an improved therapeutic window to overcome dose limiting toxicities in AML therapies

Lysophosphatidylcholine is a Major Component of Platelet Microvesicles Promoting Platelet Activation and Reporting Atherosclerotic Plaque Instability

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi

Abstract 690: Application of the DARPin® technology for specific targeting of tumor-associated MHC class I:peptide complexes

Fibrin-targeted direct factor Xa inhibition: construction and characterization of a recombinant factor Xa inhibitor composed of an anti-fibrin single-chain antibody and tick anticoagulant peptide

CD40 ligand mediates inflammation independently of CD40 by interaction with mac-1

A DARPin targeting activated Mac-1 is a novel diagnostic tool and potential anti-inflammatory agent in myocarditis, sepsis and myocardial infarction

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