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On Neurodegenerative Diseases, Models, and Treatment Strategies: Lessons Learned and Lessons Forgotten a Generation Following the Cholinergic Hypothesis

Experimental Neurology, 2000-06, Vol.163 (2), p.495-529

Bartus, Raymond T.

2000

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Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies

Neurobiology of disease, 2015-06, Vol.78, p.162-171

2015

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The development of the bradykinin agonist labradimil as a means to increase the permeability of the blood-brain barrier from concept to clinical evaluation

Clinical pharmacokinetics, 2001, Vol.40 (2), p.105-123

2001

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Calpain Inhibitor AK295 Attenuates Motor and Cognitive Deficits Following Experimental Brain Injury in the Rat

Proceedings of the National Academy of Sciences - PNAS, 1996-04, Vol.93 (8), p.3428-3433

1996

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Enhanced delivery of carboplatin into brain tumours with intravenous Cereport (RMP-7): dramatic differences and insight gained from dosing parameters

British Journal of Cancer, 1999-06, Vol.80 (7), p.964-970

1999

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Controlled Modulation of BBB Permeability Using the Bradykinin Agonist, RMP-7

Experimental neurology, 1996-11, Vol.142 (1), p.14-28

1996

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Sustained Delivery of Proteins for Novel Therapeutic Products

Science (American Association for the Advancement of Science), 1998-08, Vol.281 (5380), p.1161-1162

1998

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Injectable chemotherapeutic microspheres and glioma. II : Enhanced survival following implantation into deep inoperable tumors

Pharmaceutical research, 2000-07, Vol.17 (7), p.776-781

2000

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Intravenous RMP-7 selectively increases uptake of carboplatin into rat brain tumors

Cancer research (Chicago, Ill.), 1996-09, Vol.56 (17), p.3998-4005

1996

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Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors

Journal of neurosurgery, 1994-11, Vol.81 (5), p.752-758

1994

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Injectable chemotherapeutic microspheres and glioma. I : Enhanced survival following implantation into the cavity wall of debulked tumors

Pharmaceutical research, 2000-07, Vol.17 (7), p.767-775

2000

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Behavioral Efficacy of Posttraumatic Calpain Inhibition Is Not Accompanied by Reduced Spectrin Proteolysis, Cortical Lesion, or Apoptosis

Journal of cerebral blood flow and metabolism, 2000-01, Vol.20 (1), p.66-73

2000

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Postischemic administration of AK275, a calpain inhibitor, provides substantial protection against focal ischemic brain damage

Journal of cerebral blood flow and metabolism, 1994-07, Vol.14 (4), p.537-544

1994

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Unlocking the Blood–Brain Barrier: A Role for RMP-7 in Brain Tumor Therapy

Experimental neurology, 1996-10, Vol.141 (2), p.214-224

1996

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Pathway across blood-brain barrier opened by the bradykinin agonist, RMP-7

Brain research, 1995-12, Vol.705 (1), p.125-135

1995

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Time-related neuronal changes following middle cerebral artery occlusion: implications for therapeutic intervention and the role of calpain

Journal of cerebral blood flow and metabolism, 1995-11, Vol.15 (6), p.969-979

1995

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Intravenous Administration of a Transferrin Receptor Antibody-Nerve Growth Factor Conjugate Prevents the Degeneration of Cholinergic Striatal Neurons in a Model of Huntington Disease

Proceedings of the National Academy of Sciences - PNAS, 1994-09, Vol.91 (19), p.9077-9080

1994

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Central analgesic actions of loperamide following transient permeation of the blood brain barrier with Cereport™ (RMP-7)

Brain research, 1998-08, Vol.801 (1), p.259-266

1998

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Temporal ordering of pathogenic events following transient global ischemia

Brain research, 1998-04, Vol.790 (1), p.1-13

1998

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Suppression of alcohol intake by chronic naloxone treatment in P rats : Tolerance development and elevation of opiate receptor binding

Alcoholism, clinical and experimental research, 1999-11, Vol.23 (11), p.1761-1771

1999

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Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses

Nature medicine, 1999-08, Vol.5 (8), p.881-887

1999

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Cholinergic markers in Alzheimer disease

JAMA : the journal of the American Medical Association, 1999-12, Vol.282 (23), p.2208

1999

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Cereport (RMP-7) increases the permeability of human brain microvascular endothelial cell monolayers

Pharmaceutical research, 1999-09, Vol.16 (9), p.1360-1365

1999

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Lack of Evidence for Neutrophil Participation during Infarct Formation Following Focal Cerebral Ischemia in the Rat

Experimental neurology, 1996-06, Vol.139 (2), p.188-202

1996

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Permeability of the blood brain barrier by the bradykinin agonist, RMP-7: Evidence for a sensitive, auto-regulated, receptor-mediated system

Immunopharmacology, 1996-06, Vol.33 (1-3), p.270-278

1996

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On Neurodegenerative Diseases, Models, and Treatment Strategies: Lessons Learned and Lessons Forgotten a Generation Following the Cholinergic Hypothesis

Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies

The development of the bradykinin agonist labradimil as a means to increase the permeability of the blood-brain barrier from concept to clinical evaluation

Calpain Inhibitor AK295 Attenuates Motor and Cognitive Deficits Following Experimental Brain Injury in the Rat

Enhanced delivery of carboplatin into brain tumours with intravenous Cereport (RMP-7): dramatic differences and insight gained from dosing parameters

Controlled Modulation of BBB Permeability Using the Bradykinin Agonist, RMP-7

Sustained Delivery of Proteins for Novel Therapeutic Products

Injectable chemotherapeutic microspheres and glioma. II : Enhanced survival following implantation into deep inoperable tumors

Intravenous RMP-7 selectively increases uptake of carboplatin into rat brain tumors

Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors

Injectable chemotherapeutic microspheres and glioma. I : Enhanced survival following implantation into the cavity wall of debulked tumors

Behavioral Efficacy of Posttraumatic Calpain Inhibition Is Not Accompanied by Reduced Spectrin Proteolysis, Cortical Lesion, or Apoptosis

Postischemic administration of AK275, a calpain inhibitor, provides substantial protection against focal ischemic brain damage

Unlocking the Blood–Brain Barrier: A Role for RMP-7 in Brain Tumor Therapy

Pathway across blood-brain barrier opened by the bradykinin agonist, RMP-7

Time-related neuronal changes following middle cerebral artery occlusion: implications for therapeutic intervention and the role of calpain

Intravenous Administration of a Transferrin Receptor Antibody-Nerve Growth Factor Conjugate Prevents the Degeneration of Cholinergic Striatal Neurons in a Model of Huntington Disease

Central analgesic actions of loperamide following transient permeation of the blood brain barrier with Cereport™ (RMP-7)

Temporal ordering of pathogenic events following transient global ischemia

Suppression of alcohol intake by chronic naloxone treatment in P rats : Tolerance development and elevation of opiate receptor binding

Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses

Cholinergic markers in Alzheimer disease

Cereport (RMP-7) increases the permeability of human brain microvascular endothelial cell monolayers

Lack of Evidence for Neutrophil Participation during Infarct Formation Following Focal Cerebral Ischemia in the Rat

Permeability of the blood brain barrier by the bradykinin agonist, RMP-7: Evidence for a sensitive, auto-regulated, receptor-mediated system

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