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The critical roles of somatic mutations and environmental tumor-promoting agents in cancer risk

Nature genetics, 2020-11, Vol.52 (11), p.1139-1143

Balmain, Allan

2020

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Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis

Nature cell biology, 2018-06, Vol.20 (6), p.699-709

2018

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Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice

Nature communications, 2020-01, Vol.11 (1), p.394-15, Article 394

2020

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K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling

Cell, 2015-11, Vol.163 (5), p.1237-1251

2015

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Integration of multiple biological contexts reveals principles of synthetic lethality that affect reproducibility

Nature communications, 2020-05, Vol.11 (1), p.2375-12, Article 2375

2020

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Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells

Nature communications, 2021-07, Vol.12 (1), p.4288-4288, Article 4288

2021

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The mutational landscapes of genetic and chemical models of Kras-driven lung cancer

Nature (London), 2015-01, Vol.517 (7535), p.489-492

2015

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The mutational signature profile of known and suspected human carcinogens in mice

Nature genetics, 2020-11, Vol.52 (11), p.1189-1197

2020

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Keratin 16 regulates innate immunity in response to epidermal barrier breach

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (48), p.19537-19542

2013

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Air pollution's role in the promotion of lung cancer

Nature (London), 2023-04, Vol.616 (7955), p.35-36

Balmain, Allan

2023

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Peto’s paradox revisited: black box vs mechanistic approaches to understanding the roles of mutations and promoting factors in cancer

European journal of epidemiology, 2023-12, Vol.38 (12), p.1251-1258

Balmain, Allan

2023

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Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin

Developmental cell, 2019-11, Vol.51 (3), p.326-340.e4

2019

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Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate

Nature communications, 2015-04, Vol.6 (1), p.6706-6706, Article 6706

2015

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Dissociation of Epithelial and Neuroendocrine Carcinoma Lineages in the Transgenic Adenocarcinoma of Mouse Prostate Model of Prostate Cancer

The American journal of pathology, 2008, Vol.172 (1), p.236-246

2008

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Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

Journal of allergy and clinical immunology, 2013-11, Vol.132 (5), p.1121-1129

2013

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Abstract IA11: Tissue- and cell-specific functions of Hras, Kras4A, and Kras4B in skin and lung cancer

Molecular cancer research, 2020-05, Vol.18 (5_Supplement), p.IA11-IA11

Balmain, Allan

2020

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An Integrated Genome-Wide Systems Genetics Screen for Breast Cancer Metastasis Susceptibility Genes

PLoS genetics, 2016-04, Vol.12 (4), p.e1005989-e1005989

2016

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Identification of Hipk2 as an essential regulator of white fat development

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (20), p.7373-7378

2014

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Abstract IA15: Normal and cancer stem cells in multistage carcinogenesis

Cancer research (Chicago, Ill.), 2018-05, Vol.78 (10_Supplement), p.IA15-IA15

Balmain, Allan

2018

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Abstract IA06: Mutational signatures of environmental carcinogens in mouse and human cancers

Cancer prevention research (Philadelphia, Pa.), 2020-07, Vol.13 (7_Supplement), p.IA06-IA06

Balmain, Allan

2020

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Chemical Carcinogenesis Models of Cancer: Back to the Future

Annual review of cancer biology, 2017-03, Vol.1 (1), p.295-312

2017

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A model for RAS mutation patterns in cancers: finding the sweet spot

Nature reviews. Cancer, 2018-12, Vol.18 (12), p.767-777

2018

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Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice

Nature, 2007-02, Vol.445 (7129), p.761-765

2007

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Age, estrogen, and immune response in breast adenocarcinoma and adjacent normal tissue

Oncoimmunology, 2017-01, Vol.6 (11), p.e1356142-e1356142

2017

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HIPK2 represses β-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis

Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (32), p.13040-13045

2007

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The critical roles of somatic mutations and environmental tumor-promoting agents in cancer risk

Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis

Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice

K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling

Integration of multiple biological contexts reveals principles of synthetic lethality that affect reproducibility

Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer

The mutational signature profile of known and suspected human carcinogens in mice

Keratin 16 regulates innate immunity in response to epidermal barrier breach

Air pollution's role in the promotion of lung cancer

Peto’s paradox revisited: black box vs mechanistic approaches to understanding the roles of mutations and promoting factors in cancer

Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin

Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate

Dissociation of Epithelial and Neuroendocrine Carcinoma Lineages in the Transgenic Adenocarcinoma of Mouse Prostate Model of Prostate Cancer

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

Abstract IA11: Tissue- and cell-specific functions of Hras, Kras4A, and Kras4B in skin and lung cancer

An Integrated Genome-Wide Systems Genetics Screen for Breast Cancer Metastasis Susceptibility Genes

Identification of Hipk2 as an essential regulator of white fat development

Abstract IA15: Normal and cancer stem cells in multistage carcinogenesis

Abstract IA06: Mutational signatures of environmental carcinogens in mouse and human cancers

Chemical Carcinogenesis Models of Cancer: Back to the Future

A model for RAS mutation patterns in cancers: finding the sweet spot

Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice

Age, estrogen, and immune response in breast adenocarcinoma and adjacent normal tissue

HIPK2 represses β-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis

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