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Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study

The lancet oncology, 2017-01, Vol.18 (1), p.112-121

2017

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RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis

Nature communications, 2021-05, Vol.12 (1), p.2901-2901, Article 2901

2021

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Heterogeneous expression of cytokines accounts for clinical diversity and refines prognostication in CMML

Leukemia, 2019-01, Vol.33 (1), p.205-216

2019

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Phase 1 study of lenzilumab, a recombinant anti–human GM-CSF antibody, for chronic myelomonocytic leukemia

Blood, 2020-08, Vol.136 (7), p.909-913

2020

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A Multi-Institution Phase I Trial of Ruxolitinib in Patients with Chronic Myelomonocytic Leukemia (CMML)

Clinical cancer research, 2016-08, Vol.22 (15), p.3746-3754

2016

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Integrated Human and Murine Clinical Study Establishes Clinical Efficacy of Ruxolitinib in Chronic Myelomonocytic Leukemia

Clinical cancer research, 2021-11, Vol.27 (22), p.6095-6105

2021

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Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML

Clinical cancer research, 2023-08, Vol.29 (15), p.2919-2932

2023

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Combination of Farnesyltransferase and Akt Inhibitors Is Synergistic in Breast Cancer Cells and Causes Significant Breast Tumor Regression in ErbB2 Transgenic Mice

Clinical cancer research, 2011-05, Vol.17 (9), p.2852-2862

2011

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Effects of Corynebacterium bovis on Engraftment of Patient-derived Chronic-Myelomonocytic Leukemia Cells in NSGS Mice

Comparative medicine, 2019-08, Vol.69 (4), p.276-282

2019

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Activity of Suberoylanilide Hydroxamic Acid Against Human Breast Cancer Cells with Amplification of Her-2

Clinical cancer research, 2005-09, Vol.11 (17), p.6382-6389

2005

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Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin

Cancer research (Chicago, Ill.), 2005-11, Vol.65 (22), p.10536-10544

2005

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Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays

Clinical cancer research, 2018-12, Vol.24 (23), p.5918-5924

2018

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Akt2 and acid ceramidase cooperate to induce cell invasion and resistance to apoptosis

Cell cycle (Georgetown, Tex.), 2013-07, Vol.12 (13), p.2024-2032

2013

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Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-xL Binding to Bim

Marine drugs, 2014-03, Vol.12 (3), p.1335-1348

2014

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Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors

European journal of medicinal chemistry, 2015-01, Vol.90, p.315-331

2015

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Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim

Marine drugs, 2014-07, Vol.12 (8), p.4311-4325

2014

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Combined effects of novel tyrosine kinase inhibitor AMN107 and histone deacetylase inhibitor LBH589 against Bcr-Abl–expressing human leukemia cells

Blood, 2006-07, Vol.108 (2), p.645-652

2006

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Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells

Molecular cancer therapeutics, 2006-12, Vol.5 (12), p.3096-3104

2006

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Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim

Marine drugs, 2014-03, Vol.12 (3), p.1335

2014

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Synthesis and evaluation of substituted hexahydronaphthalenes as novel inhibitors of the Mcl-1/BimBH3 interaction

Bioorganic & medicinal chemistry letters, 2012-09, Vol.22 (18), p.5961-5965

2012

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Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors

The Journal of biological chemistry, 2005-07, Vol.280 (29), p.26729-26734

2005

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The Long Non-Coding RNA MALAT1 Is Necessary for Hematopoietic Stem and Progenitor Cell Expansion and Preleukemic Myeloproliferation in TET2 Deficient Myeloid Neoplasms

Blood, 2022-11, Vol.140 (Supplement 1), p.1991-1993

2022

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Single Cell Deconvolution of Myeloblasts Reveals Depletion of HSCs and Expansion of Inflammatory Granulocyte-Monocyte Progenitors (GMPs) Associated with Adverse Outcomes in Chronic Myelomonocytic Leukemia (CMML)

Blood, 2021-11, Vol.138 (Supplement 1), p.319-319

2021

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Efficacy and Safety of Ruxolitinib for Treatment of Symptomatic Chronic Myelomonocytic Leukemia (CMML): Results of a Multicenter Phase II Clinical Trial

Blood, 2022-11, Vol.140 (Supplement 1), p.1101-1103

2022

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Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study

RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis

Heterogeneous expression of cytokines accounts for clinical diversity and refines prognostication in CMML

Phase 1 study of lenzilumab, a recombinant anti–human GM-CSF antibody, for chronic myelomonocytic leukemia

Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML

A Multi-Institution Phase I Trial of Ruxolitinib in Patients with Chronic Myelomonocytic Leukemia (CMML)

Integrated Human and Murine Clinical Study Establishes Clinical Efficacy of Ruxolitinib in Chronic Myelomonocytic Leukemia

Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML

Combination of Farnesyltransferase and Akt Inhibitors Is Synergistic in Breast Cancer Cells and Causes Significant Breast Tumor Regression in ErbB2 Transgenic Mice

Effects of Corynebacterium bovis on Engraftment of Patient-derived Chronic-Myelomonocytic Leukemia Cells in NSGS Mice

Activity of Suberoylanilide Hydroxamic Acid Against Human Breast Cancer Cells with Amplification of Her-2

Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin

Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays

Akt2 and acid ceramidase cooperate to induce cell invasion and resistance to apoptosis

Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-xL Binding to Bim

Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors

Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim

Combined effects of novel tyrosine kinase inhibitor AMN107 and histone deacetylase inhibitor LBH589 against Bcr-Abl–expressing human leukemia cells

Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells

Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim

Synthesis and evaluation of substituted hexahydronaphthalenes as novel inhibitors of the Mcl-1/BimBH3 interaction

Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors

The Long Non-Coding RNA MALAT1 Is Necessary for Hematopoietic Stem and Progenitor Cell Expansion and Preleukemic Myeloproliferation in TET2 Deficient Myeloid Neoplasms

Single Cell Deconvolution of Myeloblasts Reveals Depletion of HSCs and Expansion of Inflammatory Granulocyte-Monocyte Progenitors (GMPs) Associated with Adverse Outcomes in Chronic Myelomonocytic Leukemia (CMML)

Efficacy and Safety of Ruxolitinib for Treatment of Symptomatic Chronic Myelomonocytic Leukemia (CMML): Results of a Multicenter Phase II Clinical Trial

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