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Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: Dose–response, mechanisms, and clinical implications

Toxicology and applied pharmacology, 2013-06, Vol.269 (3), p.240-249

2013

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Intracellular Signaling Mechanisms of Acetaminophen-Induced Liver Cell Death

Toxicological sciences, 2006-01, Vol.89 (1), p.31-41

2006

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Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans

Toxicology and applied pharmacology, 2014-03, Vol.275 (2), p.122-133

2014

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Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity

Food and chemical toxicology, 2015-07, Vol.81, p.62-70

2015

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Mitochondrial bax translocation accelerates DNA fragmentation and cell necrosis in a murine model of acetaminophen hepatotoxicity

The Journal of pharmacology and experimental therapeutics, 2008-01, Vol.324 (1), p.8-14

2008

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Apoptosis-Inducing Factor Modulates Mitochondrial Oxidant Stress in Acetaminophen Hepatotoxicity

Toxicological sciences, 2011-08, Vol.122 (2), p.598-605

2011

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Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice

Liver international, 2010-10, Vol.30 (9), p.1280-1292

2010

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Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity

The Journal of pharmacology and experimental therapeutics, 2005-11, Vol.315 (2), p.879-887

2005

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The Oxygen Tension Modulates Acetaminophen-Induced Mitochondrial Oxidant Stress and Cell Injury in Cultured Hepatocytes

Toxicological sciences, 2010-10, Vol.117 (2), p.515-523

2010

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Protection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioning

Toxicology and applied pharmacology, 2014-02, Vol.274 (3), p.417-424

2014

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Role of caspases in acetaminophen-induced liver injury

Life sciences (1973), 2006-03, Vol.78 (15), p.1670-1676

2006

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Apoptosis and necrosis in liver disease

Liver international, 2004-04, Vol.24 (2), p.85-89

2004

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The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury

Xenobiotica, 2015-05, Vol.45 (5), p.442-449

2015

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Effects of CXC chemokines on neutrophil activation and sequestration in hepatic vasculature

American journal of physiology: Gastrointestinal and liver physiology, 2001-11, Vol.281 (5), p.G1188-G1195

2001

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Scavenging peroxynitrite with glutathione promotes regeneration and enhances survival during acetaminophen-induced liver injury in mice

The Journal of pharmacology and experimental therapeutics, 2003-10, Vol.307 (1), p.67-73

2003

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Plasminogen Activator Inhibitor-1 Limits Liver Injury and Facilitates Regeneration after Acetaminophen Overdose

Toxicological sciences, 2008-08, Vol.104 (2), p.419-427

2008

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Lysosomal Instability and Cathepsin B Release during Acetaminophen Hepatotoxicity

Basic & clinical pharmacology & toxicology, 2012-12, Vol.111 (6), p.417-425

2012

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Generation and functional significance of CXC chemokines for neutrophil-induced liver injury during endotoxemia

American journal of physiology: Gastrointestinal and liver physiology, 2005-05, Vol.288 (5), p.G880-G886

2005

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Critical role of CXC chemokines in endotoxemic liver injury in mice

Journal of leukocyte biology, 2004-12, Vol.76 (6), p.1089-1090

2004

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The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity

Toxicology letters, 2003-10, Vol.144 (3), p.279-288

2003

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Nuclear Translocation of Endonuclease G and Apoptosis-Inducing Factor during Acetaminophen-Induced Liver Cell Injury

Toxicological sciences, 2006-11, Vol.94 (1), p.217-225

2006

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Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice

Toxicology and applied pharmacology, 2013-12, Vol.273 (3), p.524-531

2013

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Pathophysiologic Importance of E- and L-Selectin for Neutrophil-Induced Liver Injury During Endotoxemia in Mice

Hepatology (Baltimore, Md.), 2000-11, Vol.32 (5), p.990-998

2000

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Acetaminophen-Induced Oxidant Stress and Cell Injury in Cultured Mouse Hepatocytes: Protection by N-Acetyl Cysteine

Toxicological sciences, 2004-08, Vol.80 (2), p.343-349

2004

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Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice

Hepatology (Baltimore, Md.), 2003-08, Vol.38 (2), p.355-363

2003

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Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: Dose–response, mechanisms, and clinical implications

Intracellular Signaling Mechanisms of Acetaminophen-Induced Liver Cell Death

Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans

Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity

Mitochondrial bax translocation accelerates DNA fragmentation and cell necrosis in a murine model of acetaminophen hepatotoxicity

Apoptosis-Inducing Factor Modulates Mitochondrial Oxidant Stress in Acetaminophen Hepatotoxicity

Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice

Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity

The Oxygen Tension Modulates Acetaminophen-Induced Mitochondrial Oxidant Stress and Cell Injury in Cultured Hepatocytes

Protection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioning

Role of caspases in acetaminophen-induced liver injury

Apoptosis and necrosis in liver disease

The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury

Effects of CXC chemokines on neutrophil activation and sequestration in hepatic vasculature

Scavenging peroxynitrite with glutathione promotes regeneration and enhances survival during acetaminophen-induced liver injury in mice

Plasminogen Activator Inhibitor-1 Limits Liver Injury and Facilitates Regeneration after Acetaminophen Overdose

Lysosomal Instability and Cathepsin B Release during Acetaminophen Hepatotoxicity

Generation and functional significance of CXC chemokines for neutrophil-induced liver injury during endotoxemia

Critical role of CXC chemokines in endotoxemic liver injury in mice

The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity

Nuclear Translocation of Endonuclease G and Apoptosis-Inducing Factor during Acetaminophen-Induced Liver Cell Injury

Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice

Pathophysiologic Importance of E- and L-Selectin for Neutrophil-Induced Liver Injury During Endotoxemia in Mice

Acetaminophen-Induced Oxidant Stress and Cell Injury in Cultured Mouse Hepatocytes: Protection by N-Acetyl Cysteine

Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice

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