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Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis

British journal of pharmacology, 2010-02, Vol.159 (4), p.842-855

2010

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DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signaling

Science (American Association for the Advancement of Science), 2005-11, Vol.310 (5751), p.1187-1191

2005

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The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon‐like peptide‐1 release

British journal of pharmacology, 2009-06, Vol.157 (4), p.633-644

2009

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Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition

Neuropsychopharmacology (New York, N.Y.), 2016-03, Vol.41 (4), p.1080-1092

2016

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The activity of cAMP-phosphodiesterase 4D7 (PDE4D7) is regulated by protein kinase A-dependent phosphorylation within its unique N-terminus

FEBS letters, 2015-03, Vol.589 (6), p.750-755

2015

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Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract

FEBS letters, 2005-06, Vol.579 (15), p.3264-3270

2005

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Arrestin times for compartmentalised cAMP signalling and phosphodiesterase-4 enzymes

Current opinion in cell biology, 2005-04, Vol.17 (2), p.129-134

2005

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β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (3), p.940-945

2003

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Mixed species biofilms of Candida albicans and Staphylococcus epidermidis

Journal of medical microbiology, 2002-04, Vol.51 (4), p.344-349

2002

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10 Sumoylation of essential cardiac signalling proteins: preliminary evidence

Heart (British Cardiac Society), 2015-11, Vol.101 (Suppl 6), p.A4-A4

2015

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Targeting of Cyclic AMP Degradation to$\beta_{2}-Adrenergic$Receptors by$\beta-Arrestins

Science (American Association for the Advancement of Science), 2002-10, Vol.298 (5594), p.834-836

2002

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Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A‐mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)

British journal of pharmacology, 2002-06, Vol.136 (3), p.421-433

2002

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Role of dimorphism in the development of Candida albicans biofilms

Journal of medical microbiology, 1999-07, Vol.48 (7), p.671-679

1999

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Attenuation of the Activity of the cAMP-specific Phosphodiesterase PDE4A5 by Interaction with the Immunophilin XAP2

The Journal of biological chemistry, 2003-08, Vol.278 (35), p.33351-33363

2003

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Effect of growth rate on resistance of Candida albicans biofilms to antifungal agents

Antimicrobial agents and chemotherapy, 1998-08, Vol.42 (8), p.1900-1905

1998

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The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579

The EMBO journal, 1999-02, Vol.18 (4), p.893-903

1999

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ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions

The Journal of biological chemistry, 2000-06, Vol.275 (22), p.16609-16617

2000

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Differential expression of PDE4 cAMP phosphodiesterase isoforms in inflammatory cells of smokers with COPD, smokers without COPD, and nonsmokers

American journal of physiology. Lung cellular and molecular physiology, 2004-08, Vol.287 (2), p.L332-L343

2004

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Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte‐macrophage differentiation of human U937 cells

British journal of pharmacology, 2004-05, Vol.142 (2), p.339-351

2004

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The Unique Amino-terminal Region of the PDE4D5 cAMP Phosphodiesterase Isoform Confers Preferential Interaction with β-Arrestins

The Journal of biological chemistry, 2003-12, Vol.278 (49), p.49230-49238

2003

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Sub‐family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP‐specific phosphodiesterases

British journal of pharmacology, 2000-10, Vol.131 (4), p.811-819

2000

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The role of ERK2 docking and phosphorylation of PDE4 cAMP phosphodiesterase isoforms in mediating cross-talk between the cAMP and ERK signalling pathways

Biochemical Society transactions, 2003-12, Vol.31 (Pt 6), p.1186-1190

2003

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[48] Candida biofilms and their susceptibility to antifungal agents

Methods in Enzymology, 1999, Vol.310, p.644-656

1999

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Production of extracellular matrix by Candida albicans biofilms

Journal of medical microbiology, 1998-03, Vol.47 (3), p.253-256

1998

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Iron-Limited Biofilms of Candida albicans and Their Susceptibility to Amphotericin B

Antimicrobial Agents and Chemotherapy, 1998-08, Vol.42 (8), p.2146-2149

1998

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Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis

DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signaling

The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon‐like peptide‐1 release

Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition

The activity of cAMP-phosphodiesterase 4D7 (PDE4D7) is regulated by protein kinase A-dependent phosphorylation within its unique N-terminus

Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract

Arrestin times for compartmentalised cAMP signalling and phosphodiesterase-4 enzymes

β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi

Mixed species biofilms of Candida albicans and Staphylococcus epidermidis

10 Sumoylation of essential cardiac signalling proteins: preliminary evidence

Targeting of Cyclic AMP Degradation to$\beta_{2}-Adrenergic$Receptors by$\beta-Arrestins

Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A‐mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)

Role of dimorphism in the development of Candida albicans biofilms

Attenuation of the Activity of the cAMP-specific Phosphodiesterase PDE4A5 by Interaction with the Immunophilin XAP2

Effect of growth rate on resistance of Candida albicans biofilms to antifungal agents

The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579

ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions

Differential expression of PDE4 cAMP phosphodiesterase isoforms in inflammatory cells of smokers with COPD, smokers without COPD, and nonsmokers

Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte‐macrophage differentiation of human U937 cells

The Unique Amino-terminal Region of the PDE4D5 cAMP Phosphodiesterase Isoform Confers Preferential Interaction with β-Arrestins

Sub‐family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP‐specific phosphodiesterases

The role of ERK2 docking and phosphorylation of PDE4 cAMP phosphodiesterase isoforms in mediating cross-talk between the cAMP and ERK signalling pathways

[48] Candida biofilms and their susceptibility to antifungal agents

Production of extracellular matrix by Candida albicans biofilms

Iron-Limited Biofilms of Candida albicans and Their Susceptibility to Amphotericin B

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