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The rational use of animal models in the evaluation of novel bone regenerative therapies

Bone (New York, N.Y.), 2015-01, Vol.70, p.73-86

2015

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Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA

Arthritis research & therapy, 2015-11, Vol.17 (313), p.315-315, Article 315

2015

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Nanoparticle contrast-enhanced micro-CT: A preclinical tool for the 3D imaging of liver and spleen in longitudinal mouse studies

Journal of pharmacological and toxicological methods, 2019-03, Vol.96, p.67-77

2019

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Therapeutic Effects of FGF23 c‐tail Fc in a Murine Preclinical Model of X‐Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption

Journal of bone and mineral research, 2017-10, Vol.32 (10), p.2062-2073

2017

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Patient-derived xenografts reveal limits to PI3K/mTOR-and MEK-mediated inhibition of bladder cancer

Cancer chemotherapy and pharmacology, 2014-03, Vol.73 (3), p.525-538

2014

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Effects of Monoclonal Antibodies against Nerve Growth Factor on Healthy Bone and Joint Tissues in Mice, Rats, and Monkeys: Histopathologic, Biomarker, and Microcomputed Tomographic Assessments

Toxicologic pathology, 2018-06, Vol.46 (4), p.408-420

2018

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Metabolic Syndrome and Bone: Pharmacologically Induced Diabetes has Deleterious Effect on Bone in Growing Obese Rats

Calcified tissue international, 2018-06, Vol.102 (6), p.683-694

2018

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Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model

Cancer biology & therapy, 2009-05, Vol.8 (9), p.856-865

2009

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Models of hepatocellular carcinoma and biomarker strategy

Cancers, 2010-07, Vol.2 (3), p.1441-1452

2010

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Nerve growth factor inhibition with tanezumab influences weight-bearing and subsequent cartilage damage in the rat medial meniscal tear model

Annals of the rheumatic diseases, 2017-01, Vol.76 (1), p.295

2017

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Comparative Bone Anatomy of Commonly Used Laboratory Animals: Implications for Drug Discovery

Comparative medicine, 2011-02, Vol.61 (1), p.76-85

2011

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Correlation between μCT imaging, histology and functional capacity of the osteoarthritic knee in the rat model of osteoarthritis

Journal of translational medicine, 2015-08, Vol.13 (1), p.276-276, Article 276

2015

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Patient-derived xenografts reveal limits to PI3K/mTOR- and MEK-mediated inhibition of bladder cancer

Cancer chemotherapy and pharmacology, 2014-03, Vol.73 (3), p.525-538

2014

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Targeting of therapeutic agents to bone to treat metastatic cancer

Advanced drug delivery reviews, 2005-05, Vol.57 (7), p.995-1010

Bagi, Cedo M.

2005

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Dual Focal Adhesion Kinase/Pyk2 Inhibitor Has Positive Effects on Bone Tumors : Implications for Bone Metastases

Cancer, 2008-05, Vol.112 (10), p.2313-2321

2008

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The use of micro-CT to evaluate cortical bone geometry and strength in nude rats: Correlation with mechanical testing, pQCT and DXA

Bone (New York, N.Y.), 2006, Vol.38 (1), p.136-144

2006

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Age‐related Changes in Marmoset Trabecular and Cortical Bone and Response to Alendronate Therapy Resemble Human Bone Physiology and Architecture

Anatomical record (Hoboken, N.J. : 2007), 2007-08, Vol.290 (8), p.1005-1016

2007

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Oral Administration of Soluble Guanylate Cyclase Agonists to Rats Results in Osteoclastic Bone Resorption and Remodeling with New Bone Formation in the Appendicular and Axial Skeleton

Toxicologic pathology, 2015-04, Vol.43 (3), p.411-423

2015

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Alternative approach to assessment of bone quality using micro-computed tomography

Bone (New York, N.Y.), 2004-07, Vol.35 (1), p.326-333

2004

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Intermittent 1,25-D3 and calcitonin combo restores bone in OVX Rats

Bone (New York, N.Y.), 2008-03, Vol.42, p.S42-S43

2008

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Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors

Cancer, 2008-05, Vol.112 (10), p.2313-2321

2008

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4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17β-hydroxysteroid dehydrogenase. Part 3. Identification of lead candidate

Bioorganic & medicinal chemistry letters, 2006-09, Vol.16 (18), p.4965-4968

2006

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Benefit of systemically administered rhIGF‐I and rhIGF‐I/IGFBP‐3 on cancellous bone in ovariectomized rats

Journal of bone and mineral research, 1994-08, Vol.9 (8), p.1301-1312

1994

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Correlation between [mu]CT imaging, histology and functional capacity of the osteoarthritic knee in the rat model of osteoarthritis

Journal of translational medicine, 2015-08, Vol.13

2015

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Targeting of therapeutic agents to bone to treat metastatic cancer: Targeted drug delivery for musculoskeletal diseases

Advanced drug delivery reviews, 2005, Vol.57 (7), p.995-1010

BAGI, Cedo M

2005

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The rational use of animal models in the evaluation of novel bone regenerative therapies

Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA

Nanoparticle contrast-enhanced micro-CT: A preclinical tool for the 3D imaging of liver and spleen in longitudinal mouse studies

Therapeutic Effects of FGF23 c‐tail Fc in a Murine Preclinical Model of X‐Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption

Patient-derived xenografts reveal limits to PI3K/mTOR-and MEK-mediated inhibition of bladder cancer

Effects of Monoclonal Antibodies against Nerve Growth Factor on Healthy Bone and Joint Tissues in Mice, Rats, and Monkeys: Histopathologic, Biomarker, and Microcomputed Tomographic Assessments

Metabolic Syndrome and Bone: Pharmacologically Induced Diabetes has Deleterious Effect on Bone in Growing Obese Rats

Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model

Models of hepatocellular carcinoma and biomarker strategy

Nerve growth factor inhibition with tanezumab influences weight-bearing and subsequent cartilage damage in the rat medial meniscal tear model

Comparative Bone Anatomy of Commonly Used Laboratory Animals: Implications for Drug Discovery

Correlation between μCT imaging, histology and functional capacity of the osteoarthritic knee in the rat model of osteoarthritis

Patient-derived xenografts reveal limits to PI3K/mTOR- and MEK-mediated inhibition of bladder cancer

Targeting of therapeutic agents to bone to treat metastatic cancer

Dual Focal Adhesion Kinase/Pyk2 Inhibitor Has Positive Effects on Bone Tumors : Implications for Bone Metastases

The use of micro-CT to evaluate cortical bone geometry and strength in nude rats: Correlation with mechanical testing, pQCT and DXA

Age‐related Changes in Marmoset Trabecular and Cortical Bone and Response to Alendronate Therapy Resemble Human Bone Physiology and Architecture

Oral Administration of Soluble Guanylate Cyclase Agonists to Rats Results in Osteoclastic Bone Resorption and Remodeling with New Bone Formation in the Appendicular and Axial Skeleton

Alternative approach to assessment of bone quality using micro-computed tomography

Intermittent 1,25-D3 and calcitonin combo restores bone in OVX Rats

Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors

4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17β-hydroxysteroid dehydrogenase. Part 3. Identification of lead candidate

Benefit of systemically administered rhIGF‐I and rhIGF‐I/IGFBP‐3 on cancellous bone in ovariectomized rats

Correlation between [mu]CT imaging, histology and functional capacity of the osteoarthritic knee in the rat model of osteoarthritis

Targeting of therapeutic agents to bone to treat metastatic cancer: Targeted drug delivery for musculoskeletal diseases

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