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Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden

Proceedings of the National Academy of Sciences - PNAS, 2017-12, Vol.114 (51), p.E10981-E10990

2017

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Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes

Nature communications, 2018-05, Vol.9 (1), p.1921-11, Article 1921

2018

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A mechanism of T cell dependent selection of antigen engaged Germinal Center B cells

PloS one, 2018-08, Vol.13 (8), p.e0200241-e0200241

2018

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Detection of Tumor PIK3CA Status in Metastatic Breast Cancer Using Peripheral Blood

Clinical cancer research, 2012-06, Vol.18 (12), p.3462-3469

2012

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Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth

Cancer biology & therapy, 2012-10, Vol.13 (12), p.1185-1194

2012

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DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13), p.3445-3454

2019

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Integration of the Transcriptome and Genome-Wide Landscape of BRD2 and BRD4 Binding Motifs Identifies Key Superenhancer Genes and Reveals the Mechanism of Bet Inhibitor Action in Rheumatoid Arthritis Synovial Fibroblasts

The Journal of immunology (1950), 2021-01, Vol.206 (2), p.422-431

2021

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TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1

The Journal of immunology (1950), 2017-12, Vol.199 (12), p.4091-4102

2017

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Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (43), p.17773-17778

2011

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Subtype and pathway specific responses to anticancer compounds in breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.2724-2729

2012

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Molecular Target Class Is Predictive of In vitro Response Profile

Cancer research (Chicago, Ill.), 2010-05, Vol.70 (9), p.3677-3686

2010

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Transcription factor expression repertoire basis for epigenetic and transcriptional subtypes of colorectal cancers

Proceedings of the National Academy of Sciences - PNAS, 2023-08, Vol.120 (31), p.e2301536120-e2301536120

2023

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

Nature genetics, 2000-07, Vol.25 (3), p.269-277

2000

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Gut-Restricted Selective Cyclooxygenase‑2 (COX-2) Inhibitors for Chemoprevention of Colorectal Cancer

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.11570-11596

2021

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Consensus Coding Sequences of Human Breast and Colorectal Cancers

Science (American Association for the Advancement of Science), 2006-10, Vol.314 (5797), p.268-274

2006

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The PIK3CA gene is mutated with high frequency in human breast cancers

Cancer biology & therapy, 2004-08, Vol.3 (8), p.772-775

2004

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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

Nature (London), 2002-04, Vol.416 (6880), p.552-556

2002

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De novo CpG island methylation in human cancer cells

Cancer research (Chicago, Ill.), 2006-01, Vol.66 (2), p.682-692

2006

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Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells

Cancer research (Chicago, Ill.), 2009-11, Vol.69 (21), p.8275-8283

2009

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

Nature genetics, 1999-01, Vol.21 (1), p.103-107

1999

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Knockin of mutant PIK3CA activates multiple oncogenic pathways

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2835-2840

2009

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Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene

Cancer cell, 2003, Vol.3 (1), p.89-95

2003

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Duel nature of TGF-β signaling: tumor suppressor vs. tumor promoter

Current opinion in oncology, 2005-01, Vol.17 (1), p.49-54

2005

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Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras-mediated transformation

Cancer research (Chicago, Ill.), 2007-09, Vol.67 (18), p.8460-8467

2007

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REPLY TO HAFFNER ET AL: DNA hypomethylation renders tumors more immunogenic

Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (37), p.E8583-E8584

2018

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Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes

A mechanism of T cell dependent selection of antigen engaged Germinal Center B cells

Detection of Tumor PIK3CA Status in Metastatic Breast Cancer Using Peripheral Blood

Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth

DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer

Integration of the Transcriptome and Genome-Wide Landscape of BRD2 and BRD4 Binding Motifs Identifies Key Superenhancer Genes and Reveals the Mechanism of Bet Inhibitor Action in Rheumatoid Arthritis Synovial Fibroblasts

TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1

Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells

Subtype and pathway specific responses to anticancer compounds in breast cancer

Molecular Target Class Is Predictive of In vitro Response Profile

Transcription factor expression repertoire basis for epigenetic and transcriptional subtypes of colorectal cancers

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

Gut-Restricted Selective Cyclooxygenase‑2 (COX-2) Inhibitors for Chemoprevention of Colorectal Cancer

Consensus Coding Sequences of Human Breast and Colorectal Cancers

The PIK3CA gene is mutated with high frequency in human breast cancers

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

De novo CpG island methylation in human cancer cells

Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

Knockin of mutant PIK3CA activates multiple oncogenic pathways

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene

Duel nature of TGF-β signaling: tumor suppressor vs. tumor promoter

Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras-mediated transformation

REPLY TO HAFFNER ET AL: DNA hypomethylation renders tumors more immunogenic

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