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Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na+/H+ exchanger, lowering of cytosolic Na+ and vasodilation

Diabetologia, 2018-03, Vol.61 (3), p.722-726

2018

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RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling

Circulation (New York, N.Y.), 2018-09, Vol.138 (13), p.1330-1342

2018

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Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients

Frontiers in physiology, 2018-11, Vol.9, p.1575-1575

2018

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Empagliflozin reduces oxidative stress through inhibition of the novel inflammation/NHE/[Na+]c/ROS-pathway in human endothelial cells

Biomedicine & pharmacotherapy, 2022-02, Vol.146, p.112515-112515, Article 112515

2022

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Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Can Be Improved by Lowering Accumulation of Fatty Acid Oxidation Intermediates

International journal of molecular sciences, 2020-04, Vol.21 (7), p.2589

2020

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Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells

Frontiers in physiology, 2023, Vol.14, p.1179131-1179131

2023

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Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K + channel

Nature communications, 2018-10, Vol.9 (1), p.4357-15, Article 4357

2018

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A heterozygous deletion mutation in the cardiac sodium channel gene SCN5A with loss- and gain-of-function characteristics manifests as isolated conduction disease, without signs of Brugada or long QT syndrome

PloS one, 2013-06, Vol.8 (6), p.e67963

2013

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Two Distinct Congenital Arrhythmias Evoked by a Multidysfunctional Na+ Channel

Circulation research, 2000-05, Vol.86 (9), p.e91-e97

2000

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Chronic inhibition of na(+)/h(+)-exchanger in the heart

Current vascular pharmacology, 2006-01, Vol.4 (1), p.23

Baartscheer, Antonius

2006

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Contribution of Sodium Channel Mutations to Bradycardia and Sinus Node Dysfunction in LQT3 Families

Circulation research, 2003-05, Vol.92 (9), p.976-983

2003

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Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits

Diabetologia, 2017-03, Vol.60 (3), p.568-573

2017

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Sodium ion transporters as new therapeutic targets in heart failure

Cardiovascular & hematological agents in medicinal chemistry, 2008-10, Vol.6 (4), p.229

2008

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Ionic mechanism of delayed afterdepolarizations in ventricular cells isolated from human end-stage failing hearts

Circulation (New York, N.Y.), 2001-11, Vol.104 (22), p.2728-2733

2001

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Delayed ischaemic contracture onset by empagliflozin associates with NHE1 inhibition and is dependent on insulin in isolated mouse hearts

Cardiovascular research, 2019-08, Vol.115 (10), p.1533-1545

2019

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Dietary fish oil reduces the incidence of triggered arrhythmias in pig ventricular myocytes

Heart rhythm, 2007-11, Vol.4 (11), p.1452-1460

2007

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Is IGF‐1 a useful inhibitor of Na+/H+‐exchanger activity?

Acta Physiologica, 2018-10, Vol.224 (2), p.e13164-n/a

2018

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Sodium-glucose co-transporter 2 inhibitor empagliflozin inhibits the cardiac Na+/H+ exchanger 1: persistent inhibition under various experimental conditions

Cardiovascular research, 2021-12, Vol.117 (14), p.2699-2701

2021

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Chronically elevated branched chain amino acid levels are pro-arrhythmic

Cardiovascular research, 2022-06, Vol.118 (7), p.1742-1757

2022

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Enhanced late sodium current underlies pro-arrhythmic intracellular sodium and calcium dysregulation in murine sodium channelopathy

International journal of cardiology, 2018-07, Vol.263, p.54-62

2018

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Letter by Baartscheer et al Regarding Editorial, “Matter of Fat: Are Lipids Antiarrhythmic?”

Circulation. Arrhythmia and electrophysiology, 2016-03, Vol.9 (3), p.e003933-e003933

2016

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Nur77 protects against adverse cardiac remodelling by limiting neuropeptide Y signalling in the sympathoadrenal-cardiac axis

Cardiovascular research, 2018-10, Vol.114 (12), p.1617-1628

2018

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Abstract 477: Nuclear Receptor Nur77 Modulates Cardiac Function via Neuropeptide Y and Neuropeptide Y Receptor 1 Signalling

Circulation research, 2017-07, Vol.121 (suppl_1)

2017

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Empagliflozin decreases myocardial cytoplasmic Na^sup +^ through inhibition of the cardiac Na^sup +^/H^sup +^ exchanger in rats and rabbits

Diabetologia, 2017-03, Vol.60 (3), p.568

2017

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Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na+/H+ exchanger, lowering of cytosolic Na+ and vasodilation

RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling

Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients

Empagliflozin reduces oxidative stress through inhibition of the novel inflammation/NHE/[Na+]c/ROS-pathway in human endothelial cells

Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Can Be Improved by Lowering Accumulation of Fatty Acid Oxidation Intermediates

Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells

Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K + channel

Sphingosine‐1‐Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning

A heterozygous deletion mutation in the cardiac sodium channel gene SCN5A with loss- and gain-of-function characteristics manifests as isolated conduction disease, without signs of Brugada or long QT syndrome

Two Distinct Congenital Arrhythmias Evoked by a Multidysfunctional Na+ Channel

Chronic inhibition of na(+)/h(+)-exchanger in the heart

Contribution of Sodium Channel Mutations to Bradycardia and Sinus Node Dysfunction in LQT3 Families

Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits

Sodium ion transporters as new therapeutic targets in heart failure

Ionic mechanism of delayed afterdepolarizations in ventricular cells isolated from human end-stage failing hearts

Delayed ischaemic contracture onset by empagliflozin associates with NHE1 inhibition and is dependent on insulin in isolated mouse hearts

Dietary fish oil reduces the incidence of triggered arrhythmias in pig ventricular myocytes

Is IGF‐1 a useful inhibitor of Na+/H+‐exchanger activity?

Sodium-glucose co-transporter 2 inhibitor empagliflozin inhibits the cardiac Na+/H+ exchanger 1: persistent inhibition under various experimental conditions

Chronically elevated branched chain amino acid levels are pro-arrhythmic

Enhanced late sodium current underlies pro-arrhythmic intracellular sodium and calcium dysregulation in murine sodium channelopathy

Letter by Baartscheer et al Regarding Editorial, “Matter of Fat: Are Lipids Antiarrhythmic?”

Nur77 protects against adverse cardiac remodelling by limiting neuropeptide Y signalling in the sympathoadrenal-cardiac axis

Abstract 477: Nuclear Receptor Nur77 Modulates Cardiac Function via Neuropeptide Y and Neuropeptide Y Receptor 1 Signalling

Empagliflozin decreases myocardial cytoplasmic Na^sup +^ through inhibition of the cardiac Na^sup +^/H^sup +^ exchanger in rats and rabbits

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