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Acyl coenzyme A:cholesterol acyl transferase in macrophages utilizes a cellular pool of cholesterol oxidase-accessible cholesterol as substrate

The Journal of biological chemistry, 1988-01, Vol.263 (3), p.1266-1272

1988

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Discovery of Potent Orally Active Thrombin Receptor (Protease Activated Receptor 1) Antagonists as Novel Antithrombotic Agents

Journal of medicinal chemistry, 2005-09, Vol.48 (19), p.5884-5887

2005

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Potent, low molecular weight thrombin receptor antagonists

Bioorganic & medicinal chemistry letters, 2001-11, Vol.11 (21), p.2851-2853

2001

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Inhibition of cellular action of thrombin by N3-cyclopropyl-7-{[4-(1-methylethyl)phenyl]methyl}-7H-pyrrolo[3,2-f]quinazoline- 1,3-diamine (SCH 79797), a nonpeptide thrombin receptor antagonist

Biochemical pharmacology, 2000-11, Vol.60 (10), p.1425-1434

2000

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Protein synthesis inhibition in mouse peritoneal macrophages results in increased acyl coenzyme A:cholesterol acyl transferase activity and cholesteryl ester accumulation in the presence of native low density lipoprotein

The Journal of biological chemistry, 1987-09, Vol.262 (25), p.12175-12181

1987

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Foam cell-forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity

The Journal of clinical investigation, 1987-02, Vol.79 (2), p.418-426

1987

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Development of proteinase-activated receptor 1 antagonists as therapeutic agents for thrombosis, restenosis and inflammatory diseases

Current pharmaceutical design, 2003-01, Vol.9 (28), p.2349

2003

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Discovery and synthesis of a novel series of quinoline-based thrombin receptor (PAR-1) antagonists

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1544-1548

2006

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Hypocholesterolemic activity of a novel inhibitor of cholesterol absorption, SCH 48461

Atherosclerosis, 1995-05, Vol.115 (1), p.45-63

1995

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Binding of a Thrombin Receptor Tethered Ligand Analogue to Human Platelet Thrombin Receptor

Molecular pharmacology, 1997-02, Vol.51 (2), p.350-356

1997

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Structure-activity relationships of pyrroloquinazolines as thrombin receptor antagonists

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (14), p.2073-2078

1999

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Inhibition of cellular action of thrombin by N3-cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3, 2-f]quinazoline-1,3-diamine (SCH 79797), a nonpeptide thrombin receptor antagonist

Biochemical pharmacology, 2000-11, Vol.60 (10), p.1425-1434

2000

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Novel inhibitors of cholesteryl ester transfer protein

Bioorganic & medicinal chemistry letters, 1995-09, Vol.5 (17), p.2005-2010

1995

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Cyclic nucleotide phosphodiesterase isozymes in rat mesangial cells

European journal of pharmacology, 1995-03, Vol.289 (1), p.49-57

1995

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Substituted 1,3,5-triazines as cholesteryl ester transfer protein inhibitors

Bioorganic & medicinal chemistry letters, 1996-04, Vol.6 (7), p.919-922

1996

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Huypocholesterolemic activity of a novel inhibitor of cholesterol absorption, SCH 48431

Atherosclerosis, 1995, Vol.115 (1), p.45-63

1995

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Rabbit and human liver contain a novel pentacyclic triterpene ester with acyl-CoA: cholesterol acyltransferase inhibitory activity

The Journal of biological chemistry, 1990-05, Vol.265 (14), p.8042-8051

1990

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Effects of acyl-CoA: Cholesterol O-acyltransferase inhibition on cholesterol absorption and plasma lipoprotein composition in hamsters

Comparative biochemistry and physiology. A, Comparative physiology, 1991, Vol.99 (4), p.665-670

1991

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Cyclic nucleotide phosphodiesterase isozymes in rat mesanglial cells

European journal of pharmacology. Molecular pharmacology section, 1995, Vol.289 (1), p.49-57

1995

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ChemInform Abstract: Substituted 1,3,5-Triazines as Cholesteryl Ester Transfer Protein Inhibitors

ChemInform, 1996-08, Vol.27 (35), p.no-no

1996

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ChemInform Abstract: Wiedendiol-A and -B, Cholesteryl Ester Transfer Protein Inhibitors from the Marine Sponge Xestospongia wiedenmayeri

ChemInform, 1995-08, Vol.26 (31), p.no-no

1995

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Label-Free, LC-MS-Based Assays to Quantitate Small-Molecule Antagonist Binding to the Mammalian BLT1 Receptor

SLAS discovery, 2017-10, Vol.22 (9), p.1131-1141

2017

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Acyl coenzyme A:cholesterol acyl transferase in macrophages utilizes a cellular pool of cholesterol oxidase-accessible cholesterol as substrate

Discovery of Potent Orally Active Thrombin Receptor (Protease Activated Receptor 1) Antagonists as Novel Antithrombotic Agents

Potent, low molecular weight thrombin receptor antagonists

Inhibition of cellular action of thrombin by N3-cyclopropyl-7-{[4-(1-methylethyl)phenyl]methyl}-7H-pyrrolo[3,2-f]quinazoline- 1,3-diamine (SCH 79797), a nonpeptide thrombin receptor antagonist

Protein synthesis inhibition in mouse peritoneal macrophages results in increased acyl coenzyme A:cholesterol acyl transferase activity and cholesteryl ester accumulation in the presence of native low density lipoprotein

Foam cell-forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity

Development of proteinase-activated receptor 1 antagonists as therapeutic agents for thrombosis, restenosis and inflammatory diseases

Discovery and synthesis of a novel series of quinoline-based thrombin receptor (PAR-1) antagonists

Hypocholesterolemic activity of a novel inhibitor of cholesterol absorption, SCH 48461

Binding of a Thrombin Receptor Tethered Ligand Analogue to Human Platelet Thrombin Receptor

Structure-activity relationships of pyrroloquinazolines as thrombin receptor antagonists

Potent Tetracyclic Guanine Inhibitors of PDE1 and PDE5 Cyclic Guanosine Monophosphate Phosphodiesterases with Oral Antihypertensive Activity

Inhibition of cellular action of thrombin by N3-cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3, 2-f]quinazoline-1,3-diamine (SCH 79797), a nonpeptide thrombin receptor antagonist

Novel inhibitors of cholesteryl ester transfer protein

Cyclic nucleotide phosphodiesterase isozymes in rat mesangial cells

Substituted 1,3,5-triazines as cholesteryl ester transfer protein inhibitors

Huypocholesterolemic activity of a novel inhibitor of cholesterol absorption, SCH 48431

Rabbit and human liver contain a novel pentacyclic triterpene ester with acyl-CoA: cholesterol acyltransferase inhibitory activity

Effects of acyl-CoA: Cholesterol O-acyltransferase inhibition on cholesterol absorption and plasma lipoprotein composition in hamsters

Cyclic nucleotide phosphodiesterase isozymes in rat mesanglial cells

ChemInform Abstract: Substituted 1,3,5-Triazines as Cholesteryl Ester Transfer Protein Inhibitors

ChemInform Abstract: Wiedendiol-A and -B, Cholesteryl Ester Transfer Protein Inhibitors from the Marine Sponge Xestospongia wiedenmayeri

Label-Free, LC-MS-Based Assays to Quantitate Small-Molecule Antagonist Binding to the Mammalian BLT1 Receptor

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