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Immune Sensing of DNA

Immunity (Cambridge, Mass.), 2013-05, Vol.38 (5), p.870-880

2013

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Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

Immunity (Cambridge, Mass.), 2012-04, Vol.36 (4), p.561-571

2012

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The history of Toll-like receptors - redefining innate immunity

Nature reviews. Immunology, 2013-06, Vol.13 (6), p.453

2013

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Evaluating the role of Toll-like receptors in diseases of the central nervous system

Biochemical pharmacology, 2011-04, Vol.81 (7), p.825-837

2011

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The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

Immunity (Cambridge, Mass.), 2016-03, Vol.44 (3), p.597-608

2016

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Activation of host pattern recognition receptors by viruses

Current opinion in microbiology, 2010-08, Vol.13 (4), p.503-507

2010

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IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

Nature communications, 2017-02, Vol.8 (1), p.14392-15, Article 14392

2017

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Detection of Viral Infections by Innate Immunity

Biochemical pharmacology, 2021-01, Vol.183, p.114316-114316, Article 114316

2021

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Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors

Nature communications, 2017-12, Vol.8 (1), p.1985-15, Article 1985

2017

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IFI16 is an innate immune sensor for intracellular DNA

Nature immunology, 2010-11, Vol.11 (11), p.997

2010

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Molluscum Contagiosum Virus Protein MC008 Targets NF-κB Activation by Inhibiting Ubiquitination of NEMO

Journal of virology, 2023-03, Vol.97 (3), p.e0010823

2023

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Innate sensing of bacterial cyclic dinucleotides: more than just STING

Nature immunology, 2012-12, Vol.13 (12), p.1137

Bowie, Andrew G

2012

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Neuronal Toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro

Journal of neuroinflammation, 2012-10, Vol.9 (1), p.230-230, Article 698

2012

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The human adaptor SARM negatively regulates adaptor protein TRIF -dependent Toll-like receptor signaling

Nature Immunology, 2006-10, Vol.7 (10), p.1074-1081

2006

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Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7

Nature communications, 2022-01, Vol.13 (1), p.14-14, Article 14

2022

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Reactive Centre Loop Mutagenesis of SerpinB3 to Target TMPRSS2 and Furin: Inhibition of SARS-CoV-2 Cell Entry and Replication

International journal of molecular sciences, 2022-10, Vol.23 (20), p.12522

2022

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Innate immune recognition of DNA: A recent history

Virology (New York, N.Y.), 2015-05, Vol.479, p.146-152

2015

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Poxviral Protein A46 Antagonizes Toll-like Receptor 4 Signaling by Targeting BB Loop Motifs in Toll-IL-1 Receptor Adaptor Proteins to Disrupt Receptor:Adaptor Interactions

The Journal of biological chemistry, 2012-06, Vol.287 (27), p.22672-22682

2012

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TRAM is required for TLR2 endosomal signaling to type I IFN induction

The Journal of immunology (1950), 2014-12, Vol.193 (12), p.6090-6102

2014

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SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1606

2022

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Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

The Journal of immunology (1950), 2013-03, Vol.190 (5), p.2311-2319

2013

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Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7

PLoS pathogens, 2011-09, Vol.7 (9), p.e1002247-e1002247

2011

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Human Coronavirus 229E Infection Inactivates Pyroptosis Executioner Gasdermin D but Ultimately Leads to Lytic Cell Death Partly Mediated by Gasdermin E

Viruses, 2024-06, Vol.16 (6), p.898

2024

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Multi-omics characterization of the monkeypox virus infection

Nature communications, 2024-08, Vol.15 (1), p.6778-19, Article 6778

2024

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Innate immune detection of microbial nucleic acids

Trends in microbiology (Regular ed.), 2013-08, Vol.21 (8), p.413-420

2013

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Immune Sensing of DNA

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

The history of Toll-like receptors - redefining innate immunity

Evaluating the role of Toll-like receptors in diseases of the central nervous system

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

Activation of host pattern recognition receptors by viruses

IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

Detection of Viral Infections by Innate Immunity

Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors

IFI16 is an innate immune sensor for intracellular DNA

Molluscum Contagiosum Virus Protein MC008 Targets NF-κB Activation by Inhibiting Ubiquitination of NEMO

Innate sensing of bacterial cyclic dinucleotides: more than just STING

Neuronal Toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro

The human adaptor SARM negatively regulates adaptor protein TRIF -dependent Toll-like receptor signaling

Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7

Reactive Centre Loop Mutagenesis of SerpinB3 to Target TMPRSS2 and Furin: Inhibition of SARS-CoV-2 Cell Entry and Replication

Innate immune recognition of DNA: A recent history

Poxviral Protein A46 Antagonizes Toll-like Receptor 4 Signaling by Targeting BB Loop Motifs in Toll-IL-1 Receptor Adaptor Proteins to Disrupt Receptor:Adaptor Interactions

TRAM is required for TLR2 endosomal signaling to type I IFN induction

SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration

Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7

Human Coronavirus 229E Infection Inactivates Pyroptosis Executioner Gasdermin D but Ultimately Leads to Lytic Cell Death Partly Mediated by Gasdermin E

Multi-omics characterization of the monkeypox virus infection

Innate immune detection of microbial nucleic acids

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