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Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer

Molecular cancer therapeutics, 2014-04, Vol.13 (4), p.890-901

2014

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Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events

Clinical cancer research, 2011-05, Vol.17 (9), p.2734-2743

2011

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Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment

Journal for immunotherapy of cancer, 2017-12, Vol.5 (1), p.101-101, Article 101

2017

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A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis

Nature medicine, 2009-07, Vol.15 (7), p.781-787

2009

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Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome

Cancer research (Chicago, Ill.), 2007-07, Vol.67 (13), p.6383-6391

2007

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Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome

Blood, 2009-10, Vol.114 (16), p.3439-3447

2009

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Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma

Blood, 2007-11, Vol.110 (9), p.3281-3290

2007

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Molecular mechanisms of bortezomib resistant adenocarcinoma cells

PloS one, 2011-12, Vol.6 (12), p.e27996-e27996

2011

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Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047)

Journal of medicinal chemistry, 2009-05, Vol.52 (9), p.3028-3038

2009

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A Phase I Dose-Escalation and Expansion Study of Telaglenastat in Patients with Advanced or Metastatic Solid Tumors

Clinical cancer research, 2021-09, Vol.27 (18), p.4994-5003

2021

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Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

Science (American Association for the Advancement of Science), 1992-07, Vol.257 (5067), p.255-259

1992

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Telaglenastat Plus Cabozantinib or Everolimus for Advanced or Metastatic Renal Cell Carcinoma: An Open-Label Phase I Trial

Clinical cancer research, 2022-04, Vol.28 (8), p.1540-1548

2022

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The tissue effect of argon plasma coagulation on esophageal and gastric mucosa

Gastrointestinal endoscopy, 2000-09, Vol.52 (3), p.342-345

2000

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Protein-Protein Interactions Contributing to the Specificity of Intracellular Vesicular Trafficking

Science (American Association for the Advancement of Science), 1994-02, Vol.263 (5150), p.1146-1149

1994

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Pharmacokinetics, pharmacodynamics, metabolism, distribution, and excretion of carfilzomib in rats

Drug metabolism and disposition, 2011-10, Vol.39 (10), p.1873

2011

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Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms

Nature (London), 1997-11, Vol.390 (6657), p.302-305

1997

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Retrovirally Delivered Random Cyclic Peptide Libraries Yield Inhibitors of Interleukin-4 Signaling in Human B Cells

The Journal of biological chemistry, 2002-10, Vol.277 (40), p.37512-37518

2002

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Clinical activity of carfilzomib correlates with inhibition of multiple proteasome subunits: application of a novel pharmacodynamic assay

British journal of haematology, 2016-06, Vol.173 (6), p.884-895

2016

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The synaptic SNARE complex is a parallel four-stranded helical bundle

Nature structural biology, 1998-09, Vol.5 (9), p.765-769

1998

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Differential Phosphorylation of Syntaxin and Synaptosome‐Associated Protein of 25 kDa (SNAP‐25) Isoforms

Journal of neurochemistry, 1999-02, Vol.72 (2), p.614-624

1999

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Granular Cell Tumor as an Unusual Cause of Obstruction at the Hepatic Hilum: Report of a Case

Surgery today (Tokyo, Japan), 2006-10, Vol.36 (10), p.934-936

2006

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The Molecular Machinery for Secretion is Conserved from Yeast to Neurons

Proceedings of the National Academy of Sciences - PNAS, 1993-04, Vol.90 (7), p.2559-2563

1993

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Specificity and regulation of a synaptic vesicle docking complex

Neuron (Cambridge, Mass.), 1994-08, Vol.13 (2), p.353-361

1994

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The neuronal t-SNARE complex is a parallel four-helix bundle

Nature structural & molecular biology, 2001-04, Vol.8 (4), p.308-311

2001

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The syntaxin family of vesicular transport receptors

Cell, 1993-09, Vol.74 (5), p.863-873

1993

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Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer

Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events

Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment

A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis

Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome

Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome

Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma

Molecular mechanisms of bortezomib resistant adenocarcinoma cells

Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047)

A Phase I Dose-Escalation and Expansion Study of Telaglenastat in Patients with Advanced or Metastatic Solid Tumors

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

Telaglenastat Plus Cabozantinib or Everolimus for Advanced or Metastatic Renal Cell Carcinoma: An Open-Label Phase I Trial

The tissue effect of argon plasma coagulation on esophageal and gastric mucosa

Protein-Protein Interactions Contributing to the Specificity of Intracellular Vesicular Trafficking

Pharmacokinetics, pharmacodynamics, metabolism, distribution, and excretion of carfilzomib in rats

Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms

Retrovirally Delivered Random Cyclic Peptide Libraries Yield Inhibitors of Interleukin-4 Signaling in Human B Cells

Clinical activity of carfilzomib correlates with inhibition of multiple proteasome subunits: application of a novel pharmacodynamic assay

The synaptic SNARE complex is a parallel four-stranded helical bundle

Differential Phosphorylation of Syntaxin and Synaptosome‐Associated Protein of 25 kDa (SNAP‐25) Isoforms

Granular Cell Tumor as an Unusual Cause of Obstruction at the Hepatic Hilum: Report of a Case

The Molecular Machinery for Secretion is Conserved from Yeast to Neurons

Specificity and regulation of a synaptic vesicle docking complex

The neuronal t-SNARE complex is a parallel four-helix bundle

The syntaxin family of vesicular transport receptors

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