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Engineering a Stable and Selective Peptide Blocker of the Kv1.3 Channel in T Lymphocytes

Molecular pharmacology, 2009-04, Vol.75 (4), p.762-773

2009

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K + channels as targets for specific immunomodulation

Trends in pharmacological sciences (Regular ed.), 2004-05, Vol.25 (5), p.280-289

2004

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Osteoclast formation and bone resorption are inhibited by megakaryocytes

Bone (New York, N.Y.), 2006-11, Vol.39 (5), p.985-990

2006

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Potassium Channels, Memory T Cells, and Multiple Sclerosis

The Neuroscientist, 2005-12, Vol.11 (6), p.550-562

2005

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Canaux ioniques et démyélinisation : les fondements d’un traitement de l’encéphalomyélite autoimmune expérimentale (EAE) par des bloqueurs des canaux potassium

Revue neurologique, 2004-05, Vol.160 (5), p.16-27

2004

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Selective Blocking of Voltage-Gated K+ Channels Improves Experimental Autoimmune Encephalomyelitis and Inhibits T Cell Activation

The Journal of immunology (1950), 2001-01, Vol.166 (2), p.936-944

2001

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Tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) distribution in normal and pathological human bone

Bone (New York, N.Y.), 1999-03, Vol.24 (3), p.229-235

1999

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Immunolocalisation of vascular endothelial growth factor (VEGF) in human neonatal growth plate cartilage

American journal of anatomy, 1999-05, Vol.194 (4), p.519-524

1999

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Serum TIMP-1, TIMP-2, and MMP-1 in patients with systemic sclerosis, primary Raynaud's phenomenon, and in normal controls

Annals of the rheumatic diseases, 2001-09, Vol.60 (9), p.846-851

2001

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The impact of the fourth disulfide bridge in scorpion toxins of the α-KTx6 subfamily

Proteins, structure, function, and bioinformatics, 2005-12, Vol.61 (4), p.1010-1023

2005

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Discovery on Target 2007--CHI's Fifth Annual Conference. Ion channels

IDrugs : the investigational drugs journal, 2007-12, Vol.10 (12), p.851

Beeton, Christine

2007

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The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS

The Journal of clinical investigation, 2003-06, Vol.111 (11), p.1703-1713

2003

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Targeting Effector Memory T Cells with a Selective Peptide Inhibitor of Kv1.3 Channels for Therapy of Autoimmune Diseases

Molecular pharmacology, 2005-04, Vol.67 (4), p.1369-1381

2005

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Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases

Inflammation & allergy drug targets, 2011-10, Vol.10 (5), p.313-321

2011

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Insulin-like Growth Factors Require Phosphatidylinositol 3-Kinase to Signal Myogenesis: Dominant Negative p85 Expression Blocks Differentiation of L6E9 Muscle Cells

Molecular endocrinology (Baltimore, Md.), 1998-01, Vol.12 (1), p.66-77

1998

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Comparison of the kinetic properties of the lipid- and protein-kinase activities of the p110α and p110β catalytic subunits of class-Ia phosphoinositide 3-kinases

Biochemical journal, 2000-09, Vol.350 (2), p.353

2000

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Selective Blockade of T Lymphocyte K+Channels Ameliorates Experimental Autoimmune Encephalomyelitis, A Model for Multiple Sclerosis

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (24), p.13942-13947

2001

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The Voltage-Gated Potassium Channel Kv1.3 Is Highly Expressed on Inflammatory Infiltrates in Multiple Sclerosis Brain

Proceedings of the National Academy of Sciences - PNAS, 2005-08, Vol.102 (31), p.11094-11099

2005

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Natural variants of human p85 alpha phosphoinositide 3-kinase in severe insulin resistance: a novel variant with impaired insulin-stimulated lipid kinase activity

Diabetologia, 2000-03, Vol.43 (3), p.321-331

2000

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Kv1.3-Blocking 5-Phenylalkoxypsoralens: A New Class of Immunomodulators

Molecular pharmacology, 2004-06, Vol.65 (6), p.1364-1374

2004

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Circulating levels of interleukin-6 and its soluble receptor in patients with head injury and fracture

Journal of bone and joint surgery. British volume, 2004-08, Vol.86 (6), p.912-917

2004

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15 INHIBITING EFFECTOR MEMORY T CELLS WITH SHK(L5), A NOVEL PEPTIDE BLOCKER OF THE KV1.3 POTASSIUM CHANNEL

Journal of investigative medicine, 2007-01, Vol.55 (1), p.S78

2007

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Evidence for Domain-specific Recognition of SK and Kv Channels by MTX and HsTx1 Scorpion Toxins

The Journal of biological chemistry, 2004-12, Vol.279 (53), p.55690-55696

2004

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A Novel Fluorescent Toxin to Detect and Investigate Kv1.3 Channel Up-regulation in Chronically Activated T Lymphocytes

The Journal of biological chemistry, 2003-03, Vol.278 (11), p.9928-9937

2003

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Engineering a Stable and Selective Peptide Blocker of the Kv1.3 Channel in T Lymphocytes

K + channels as targets for specific immunomodulation

Osteoclast formation and bone resorption are inhibited by megakaryocytes

Potassium Channels, Memory T Cells, and Multiple Sclerosis

Canaux ioniques et démyélinisation : les fondements d’un traitement de l’encéphalomyélite autoimmune expérimentale (EAE) par des bloqueurs des canaux potassium

Selective Blocking of Voltage-Gated K+ Channels Improves Experimental Autoimmune Encephalomyelitis and Inhibits T Cell Activation

Tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) distribution in normal and pathological human bone

Immunolocalisation of vascular endothelial growth factor (VEGF) in human neonatal growth plate cartilage

Serum TIMP-1, TIMP-2, and MMP-1 in patients with systemic sclerosis, primary Raynaud's phenomenon, and in normal controls

Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response

The impact of the fourth disulfide bridge in scorpion toxins of the α-KTx6 subfamily

Discovery on Target 2007--CHI's Fifth Annual Conference. Ion channels

The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS

Targeting Effector Memory T Cells with a Selective Peptide Inhibitor of Kv1.3 Channels for Therapy of Autoimmune Diseases

Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases

Insulin-like Growth Factors Require Phosphatidylinositol 3-Kinase to Signal Myogenesis: Dominant Negative p85 Expression Blocks Differentiation of L6E9 Muscle Cells

Comparison of the kinetic properties of the lipid- and protein-kinase activities of the p110α and p110β catalytic subunits of class-Ia phosphoinositide 3-kinases

Selective Blockade of T Lymphocyte K+Channels Ameliorates Experimental Autoimmune Encephalomyelitis, A Model for Multiple Sclerosis

The Voltage-Gated Potassium Channel Kv1.3 Is Highly Expressed on Inflammatory Infiltrates in Multiple Sclerosis Brain

Natural variants of human p85 alpha phosphoinositide 3-kinase in severe insulin resistance: a novel variant with impaired insulin-stimulated lipid kinase activity

Kv1.3-Blocking 5-Phenylalkoxypsoralens: A New Class of Immunomodulators

Circulating levels of interleukin-6 and its soluble receptor in patients with head injury and fracture

15 INHIBITING EFFECTOR MEMORY T CELLS WITH SHK(L5), A NOVEL PEPTIDE BLOCKER OF THE KV1.3 POTASSIUM CHANNEL

Evidence for Domain-specific Recognition of SK and Kv Channels by MTX and HsTx1 Scorpion Toxins

A Novel Fluorescent Toxin to Detect and Investigate Kv1.3 Channel Up-regulation in Chronically Activated T Lymphocytes

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