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Identification of Tricyclic Analogs Related to Ellagic Acid as Potent/Selective Tyrosine Protein Kinase Inhibitors

Journal of medicinal chemistry, 1994-07, Vol.37 (14), p.2224-2231

1994

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Benzyloxazolidine-2,4-diones as potent hypoglycemic agents

Journal of medicinal chemistry, 1991-05, Vol.34 (5), p.1538-1544

1991

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Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain

Journal of medicinal chemistry, 2018-08, Vol.61 (15), p.6779-6800

2018

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Synthesis of t-boc-4-dimethylphosphonomethyl-L-phenylalanine

Synlett, 1994-04 (4), p.293-294

1994

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Synthesis of [19-3H] herbimycin A

Journal of labelled compounds & radiopharmaceuticals, 1992-04, Vol.31 (4), p.333-339

1992

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ChemInform Abstract: Synthesis of tert-Boc-4-dimethylphosphonomethyl-L-phenylalanine (IV)

ChemInform, 1995-01, Vol.26 (1), p.no-no

1995

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ChemInform Abstract: Selective Inhibition of the Tyrosine Kinase pp60c-src by Analogues of 5,10-Dihydropyrimido(4,5-b)quinolin-4(1H)-one

ChemInform, 1995-09, Vol.26 (37), p.no-no

1995

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ChemInform Abstract: Identification of Tricyclic Analogues Related to Ellagic Acid as Potent/Selective Tyrosine Protein Kinase Inhibitors

ChemInform, 1994-11, Vol.25 (48), p.no-no

1994

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Development of West-European PM2.5 and NO2 land use regression models incorporating satellite-derived and chemical transport modelling data

Environmental research, 2016-11, Vol.151, p.1-10

2016

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A Second-Generation Oral SARS-CoV‑2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19

Journal of medicinal chemistry, 2024-08, Vol.67 (16), p.13550-13571

2024

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PF-04859989 as a template for structure-based drug design: Identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.1961-1966

2013

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Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia

ACS medicinal chemistry letters, 2012-03, Vol.3 (3), p.187-192

2012

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A General Strategy for the Synthesis of Cyclic N-Aryl Hydroxamic Acids via Partial Nitro Group Reduction

Journal of organic chemistry, 2011-05, Vol.76 (9), p.3484-3497

2011

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Synthesis of ortho-substituted nitroaromatics via improved Negishi coupling conditions

Tetrahedron letters, 2011-10, Vol.52 (41), p.5211-5213

2011

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Management of fertility preservation in young breast cancer patients in a large breast cancer centre

Archives of gynecology and obstetrics, 2010-11, Vol.282 (5), p.547-551

2010

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Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions

ACS medicinal chemistry letters, 2013-01, Vol.4 (1), p.37-40

2013

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Short-acting 5-(trifluoromethyl)pyrido[4,3- d]pyrimidin-4(3 H)-one derivatives as orally-active calcium-sensing receptor antagonists

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (16), p.4555-4559

2009

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Discovery of hydroxamate bioisosteres as KAT II inhibitors with improved oral bioavailability and pharmacokinetics

MedChemComm, 2013, Vol.4 (1), p.125-129

2013

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Identification of Tricyclic Analogs Related to Ellagic Acid as Potent/Selective Tyrosine Protein Kinase Inhibitors

Benzyloxazolidine-2,4-diones as potent hypoglycemic agents

Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain

Synthesis of t-boc-4-dimethylphosphonomethyl-L-phenylalanine

Synthesis of [19-3H] herbimycin A

ChemInform Abstract: Synthesis of tert-Boc-4-dimethylphosphonomethyl-L-phenylalanine (IV)

ChemInform Abstract: Selective Inhibition of the Tyrosine Kinase pp60c-src by Analogues of 5,10-Dihydropyrimido(4,5-b)quinolin-4(1H)-one

ChemInform Abstract: Identification of Tricyclic Analogues Related to Ellagic Acid as Potent/Selective Tyrosine Protein Kinase Inhibitors

Development of West-European PM2.5 and NO2 land use regression models incorporating satellite-derived and chemical transport modelling data

A Second-Generation Oral SARS-CoV‑2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19

PF-04859989 as a template for structure-based drug design: Identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency

Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia

A General Strategy for the Synthesis of Cyclic N-Aryl Hydroxamic Acids via Partial Nitro Group Reduction

Synthesis of ortho-substituted nitroaromatics via improved Negishi coupling conditions

Management of fertility preservation in young breast cancer patients in a large breast cancer centre

Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions

Short-acting 5-(trifluoromethyl)pyrido[4,3- d]pyrimidin-4(3 H)-one derivatives as orally-active calcium-sensing receptor antagonists

Discovery of hydroxamate bioisosteres as KAT II inhibitors with improved oral bioavailability and pharmacokinetics

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