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Synthetic Strategies toward SGLT2 Inhibitors

Organic process research & development, 2018-04, Vol.22 (4), p.467-488

2018

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Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma

Scientific reports, 2015-11, Vol.5 (1), p.16830-16830, Article 16830

2015

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Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival

Clinical epigenetics, 2022-05, Vol.14 (1), p.68-68, Article 68

2022

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Transcriptome Analysis of Mesenchymal Stem Cells from Multiple Myeloma Patients Reveals Downregulation of Genes Involved in Cell Cycle Progression, Immune Response, and Bone Metabolism

Scientific reports, 2019-01, Vol.9 (1), p.1056-1056, Article 1056

2019

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Systems-Level Analysis of Genetic Variants Reveals Functional and Spatiotemporal Context in Treatment-resistant Schizophrenia

Molecular neurobiology, 2022-05, Vol.59 (5), p.3170-3182

2022

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IMPACT Is a Developmentally Regulated Protein in Neurons That Opposes the Eukaryotic Initiation Factor 2α Kinase GCN2 in the modulation of Neurite Outgrowth

The Journal of biological chemistry, 2013-04, Vol.288 (15), p.10860-10869

2013

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Proteomic research and diagnosis in bladder cancer: state of the art review

International Brazilian journal of urology, 2021-05, Vol.47 (3), p.503-514

2021

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Transcriptional signatures underlying dynamic phenotypic switching and novel disease biomarkers in a linear cellular model of melanoma progression

Neoplasia (New York, N.Y.), 2021-04, Vol.23 (4), p.439-455

2021

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Brain-wide mapping of c-fos expression in the single prolonged stress model and the effects of pretreatment with ACH-000029 or prazosin

Neurobiology of stress, 2020-11, Vol.13, p.100226-100226, Article 100226

2020

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Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations

Scientific reports, 2017-08, Vol.7 (1), p.7501-12, Article 7501

2017

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Transcriptional network analysis reveals that AT1 and AT2 angiotensin II receptors are both involved in the regulation of genes essential for glioma progression

PloS one, 2014-11, Vol.9 (11), p.e110934-e110934

2014

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Temporal analysis of hippocampal CA3 gene coexpression networks in a rat model of febrile seizures

Disease models & mechanisms, 2018-01, Vol.11 (1)

2018

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NLC-Based Sunscreen Formulations with Optimized Proportion of Encapsulated and Free Filters Exhibit Enhanced UVA and UVB Photoprotection

Pharmaceutics, 2024-03, Vol.16 (3), p.427

2024

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CACHE (Critical Assessment of Computational Hit-finding Experiments): A public–private partnership benchmarking initiative to enable the development of computational methods for hit-finding

Nature reviews. Chemistry, 2022-04, Vol.6 (4), p.287-295

2022

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Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model

Scientific reports, 2017-06, Vol.7 (1), p.3192-15, Article 3192

2017

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Gene co-expression and histone modification signatures are associated with melanoma progression, epithelial-to-mesenchymal transition, and metastasis

Clinical epigenetics, 2020-08, Vol.12 (1), p.127, Article 127

2020

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Comparative bioinformatics analysis of prognostic and differentially expressed genes in non-muscle and muscle invasive bladder cancer

Journal of proteomics, 2020-10, Vol.229, p.103951-103951, Article 103951

2020

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Cri-du-Chat Syndrome interactome network: Correlating genotypic variations to associated phenotypes

Gene reports, 2018-06, Vol.11, p.179-187

2018

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Intragraft transcriptional profiling of renal transplant patients with tubular dysfunction reveals mechanisms underlying graft injury and recovery

Human genomics, 2016-01, Vol.10 (1), p.2-2, Article 2

2016

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Transcriptome analysis of renal ischemia/reperfusion injury and its modulation by ischemic pre-conditioning or hemin treatment

PloS one, 2012-11, Vol.7 (11), p.e49569

2012

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The serotonergic and alpha-1 adrenergic receptor modulator ACH-000029 ameliorates anxiety-like behavior in a post-traumatic stress disorder model

Neuropharmacology, 2020-03, Vol.164, p.107912-107912, Article 107912

2020

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Discovery of ACH-000143: A Novel Potent and Peripherally Preferred Melatonin Receptor Agonist that Reduces Liver Triglycerides and Steatosis in Diet-Induced Obese Rats

Journal of medicinal chemistry, 2021-02, Vol.64 (4), p.1904-1929

2021

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Design, synthesis and antihypertensive evaluation of novel codrugs with combined angiotensin type 1 receptor antagonism and neprilysin inhibition

European journal of pharmaceutical sciences, 2021-04, Vol.159, p.105731, Article 105731

2021

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Preclinical characterization of ACH-000029, a novel anxiolytic compound acting on serotonergic and alpha-adrenergic receptors

Progress in neuro-psychopharmacology & biological psychiatry, 2019-12, Vol.95, p.109707, Article 109707

2019

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Game changers in science and technology - now and beyond

Technological forecasting & social change, 2023-08, Vol.193, p.122588, Article 122588

2023

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Synthetic Strategies toward SGLT2 Inhibitors

Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma

Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival

Transcriptome Analysis of Mesenchymal Stem Cells from Multiple Myeloma Patients Reveals Downregulation of Genes Involved in Cell Cycle Progression, Immune Response, and Bone Metabolism

Systems-Level Analysis of Genetic Variants Reveals Functional and Spatiotemporal Context in Treatment-resistant Schizophrenia

IMPACT Is a Developmentally Regulated Protein in Neurons That Opposes the Eukaryotic Initiation Factor 2α Kinase GCN2 in the modulation of Neurite Outgrowth

Proteomic research and diagnosis in bladder cancer: state of the art review

Transcriptional signatures underlying dynamic phenotypic switching and novel disease biomarkers in a linear cellular model of melanoma progression

Brain-wide mapping of c-fos expression in the single prolonged stress model and the effects of pretreatment with ACH-000029 or prazosin

Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations

Transcriptional network analysis reveals that AT1 and AT2 angiotensin II receptors are both involved in the regulation of genes essential for glioma progression

Temporal analysis of hippocampal CA3 gene coexpression networks in a rat model of febrile seizures

NLC-Based Sunscreen Formulations with Optimized Proportion of Encapsulated and Free Filters Exhibit Enhanced UVA and UVB Photoprotection

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public–private partnership benchmarking initiative to enable the development of computational methods for hit-finding

Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model

Gene co-expression and histone modification signatures are associated with melanoma progression, epithelial-to-mesenchymal transition, and metastasis

Comparative bioinformatics analysis of prognostic and differentially expressed genes in non-muscle and muscle invasive bladder cancer

Cri-du-Chat Syndrome interactome network: Correlating genotypic variations to associated phenotypes

Intragraft transcriptional profiling of renal transplant patients with tubular dysfunction reveals mechanisms underlying graft injury and recovery

Transcriptome analysis of renal ischemia/reperfusion injury and its modulation by ischemic pre-conditioning or hemin treatment

The serotonergic and alpha-1 adrenergic receptor modulator ACH-000029 ameliorates anxiety-like behavior in a post-traumatic stress disorder model

Discovery of ACH-000143: A Novel Potent and Peripherally Preferred Melatonin Receptor Agonist that Reduces Liver Triglycerides and Steatosis in Diet-Induced Obese Rats

Design, synthesis and antihypertensive evaluation of novel codrugs with combined angiotensin type 1 receptor antagonism and neprilysin inhibition

Preclinical characterization of ACH-000029, a novel anxiolytic compound acting on serotonergic and alpha-adrenergic receptors

Game changers in science and technology - now and beyond

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