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Determination of half-maximal inhibitory concentration using biosensor-based protein interaction analysis

Analytical biochemistry, 2016-09, Vol.508, p.97-103

2016

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BMP-4 Extraction from Extracellular Matrix and Analysis of Heparin-Binding Properties

Molecular biotechnology, 2022-02, Vol.64 (2), p.156-170

2022

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Smad2/3 Activation Regulates Smad1/5/8 Signaling via a Negative Feedback Loop to Inhibit 3T3-L1 Adipogenesis

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8472

2021

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Human Cerberus prevents nodal-receptor binding, inhibits nodal signaling, and suppresses nodal-mediated phenotypes

PloS one, 2015-01, Vol.10 (1), p.e0114954-e0114954

2015

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Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1

The Journal of clinical investigation, 2022-06, Vol.132 (12), p.1-13

2022

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Structural basis for potency differences between GDF8 and GDF11

BMC biology, 2017-03, Vol.15 (1), p.19-19, Article 19

2017

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Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding

The Journal of biological chemistry, 2016-05, Vol.291 (20), p.10792-10804

2016

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How Activin A Became a Therapeutic Target in Fibrodysplasia Ossificans Progressiva

Biomolecules (Basel, Switzerland), 2024-01, Vol.14 (1), p.101

2024

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Substitutions of Conserved Residues in the C-terminal Region of DnaC Cause Thermolability in Helicase Loading

The Journal of biological chemistry, 2016-02, Vol.291 (9), p.4803-4812

2016

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New Ligand Binding Function of Human Cerberus and Role of Proteolytic Processing in Regulating Ligand–Receptor Interactions and Antagonist Activity

Journal of molecular biology, 2016-02, Vol.428 (3), p.590-602

2016

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High-Throughput, Biosensor-Based Approach to Examine Bone Morphogenetic Protein (BMP)-Receptor Interactions

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1891, p.37

2019

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Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic

The Journal of biological chemistry, 2017-03, Vol.292 (10), p.4138-4151

2017

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Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice

Proceedings of the National Academy of Sciences - PNAS, 2023-08, Vol.120 (32), p.e2309967120-e2309967120

2023

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Anti-ACVRI antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressive

The Journal of clinical investigation, 2022-06, Vol.132 (12)

2022

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Anti-ACVRI antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressive by activating FOP-mutant ACVR1

The Journal of clinical investigation, 2022-06, Vol.132 (12)

2022

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Dissecting the Extracellular Mechanisms of Nodal and Activin Signaling Regulation

Aykul, Senem

2017

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Determination of half-maximal inhibitory concentration using biosensor-based protein interaction analysis

BMP-4 Extraction from Extracellular Matrix and Analysis of Heparin-Binding Properties

Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop

Smad2/3 Activation Regulates Smad1/5/8 Signaling via a Negative Feedback Loop to Inhibit 3T3-L1 Adipogenesis

Human Cerberus prevents nodal-receptor binding, inhibits nodal signaling, and suppresses nodal-mediated phenotypes

Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1

Structural basis for potency differences between GDF8 and GDF11

Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding

How Activin A Became a Therapeutic Target in Fibrodysplasia Ossificans Progressiva

Substitutions of Conserved Residues in the C-terminal Region of DnaC Cause Thermolability in Helicase Loading

New Ligand Binding Function of Human Cerberus and Role of Proteolytic Processing in Regulating Ligand–Receptor Interactions and Antagonist Activity

High-Throughput, Biosensor-Based Approach to Examine Bone Morphogenetic Protein (BMP)-Receptor Interactions

Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic

Activin E-ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice

Anti-ACVRI antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressive

Anti-ACVRI antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressive by activating FOP-mutant ACVR1

Dissecting the Extracellular Mechanisms of Nodal and Activin Signaling Regulation

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