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Evaluation of two carrier protein–angiotensin I conjugate vaccines to assess their future potential to control high blood pressure (hypertension) in man

British journal of clinical pharmacology, 2003-11, Vol.56 (5), p.505-512

2003

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From toxicological problem to therapeutic use: The discovery of the mode of action of 2‐(2‐nitro‐4‐trifluoromethylbenzoyl)‐1,3‐cyclohexanedione (NTBC), its toxicology and development as a drug

Journal of inherited metabolic disease, 1998-08, Vol.21 (5), p.498-506

1998

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Inhibition of 4-Hydroxyphenylpyruvate Dioxygenase by 2-(2-Nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione and 2-(2-Chloro-4-methanesulfonylbenzoyl)-cyclohexane-1,3-dione

Toxicology and applied pharmacology, 1995-07, Vol.133 (1), p.12-19

1995

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Thresholds in Chemical Carcinogenesis

Regulatory toxicology and pharmacology, 1995-12, Vol.22 (3), p.199-205

1995

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Vehicle effects on in vitro percutaneous absorption through rat and human skin

Pharmaceutical research, 1994-10, Vol.11 (10), p.1396-1400

1994

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Calculation of Benchmark Doses from Teratology Data

Regulatory toxicology and pharmacology, 1994-04, Vol.19 (2), p.152-167

Auton, T.R.

1994

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Empirical scoring functions. II. The testing of an empirical scoring function for the prediction of ligand-receptor binding affinities and the use of Bayesian regression to improve the quality of the model

Journal of computer-aided molecular design, 1998-09, Vol.12 (5), p.503-519

1998

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Statistical comparison of established T-cell epitope predictors against a large database of human and murine antigens

Molecular immunology, 1996-02, Vol.33 (2), p.145-155

1996

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Application of benchmark dose risk assessment methodology to developmental toxicity: an industrial view

Toxicology Letters, 1995-12, Vol.82, p.555-559

1995

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A Physiologically Based Mathematical Model of Dermal Absorption in Man

Human & experimental toxicology, 1994-01, Vol.13 (1), p.51-60

1994

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Joint Risk from Multiple Compound Exposure

Risk analysis, 1991-06, Vol.11 (2), p.181-183

Auton, T. R.

1991

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Concentration-flux relations for a multicellular biological membrane with metabolism

Mathematical biosciences, 1993-05, Vol.115 (1), p.103-117

Auton, Timothy Robert

1993

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Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes

Journal of computer-aided molecular design, 1997-09, Vol.11 (5), p.425-445

1997

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Pharmacokinetics of Fluazifop-butyl in Human Volunteers II: Dermal Dosing

Human & experimental toxicology, 1992-07, Vol.11 (4), p.247-254

1992

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PRO_SELECT: combining structure-based drug design and combinatorial chemistry for rapid lead discovery. 1. Technology

Journal of computer-aided molecular design, 1997-03, Vol.11 (2), p.193-207

1997

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Human inhalation pharmacokinetics of 1,1,2-trichloro-1,2,2-trifluoroethane (FC113)

International archives of occupational and environmental health, 1990, Vol.62 (1), p.73-78

1990

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A physiologically based mathematical model for the human inhalation pharmacokinetics of 1,1,2-trichloro-1,2,2-trifluoroethane

International archives of occupational and environmental health, 1991-01, Vol.63 (2), p.133-138

1991

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Active immunization with angiotensin I peptide analogue vaccines selectively reduces the pressor effects of exogenous angiotensin I in conscious rats

British journal of pharmacology, 2000-03, Vol.129 (6), p.1178-1182

2000

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Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine (PMD3117) in hypertensive subjects

Clinical science (1979), 2004-08, Vol.107 (2), p.167

2004

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Characterization of the interaction of 2-[2-nitro-4-(trifluoromethyl)benzoyl]-4,4,6,6,-tetramethyl- cyclohexane-1,3,5-trione with rat hepatic 4-hydroxyphenylpyruvate dioxygenase

Chemical research in toxicology, 1996-01, Vol.9 (1), p.24

1996

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The Predictive Accuracy of in Vitro Measurements for the Dermal Absorption of a Lipophilic Penetrant (Fluazifop-Butyl) through Rat and Human Skin

Fundamental and applied toxicology, 1994-08, Vol.23 (2), p.230-236

1994

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Modelling Dermal Pharmacokinetics Using in vitro Data. Part II. Fluazifop-butyl in Man

Human & experimental toxicology, 1993-05, Vol.12 (3), p.207-213

1993

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Design of active analogues of a 15-residue peptide using D-optimal design, QSAR and a combinatorial search algorithm

The journal of peptide research, 1997-01, Vol.49 (1), p.89-102

1997

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Modelling Dermal Pharmacokinetics Using in vitro Data Part I. Fluazifop-butyl in the Rat

Human & experimental toxicology, 1993-05, Vol.12 (3), p.199-206

1993

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Human inhalation pharmacokinetics of chlorodifluoromethane (HCFC22)

International archives of occupational and environmental health, 1992-12, Vol.64 (5), p.383-387

1992

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Evaluation of two carrier protein–angiotensin I conjugate vaccines to assess their future potential to control high blood pressure (hypertension) in man

From toxicological problem to therapeutic use: The discovery of the mode of action of 2‐(2‐nitro‐4‐trifluoromethylbenzoyl)‐1,3‐cyclohexanedione (NTBC), its toxicology and development as a drug

Inhibition of 4-Hydroxyphenylpyruvate Dioxygenase by 2-(2-Nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione and 2-(2-Chloro-4-methanesulfonylbenzoyl)-cyclohexane-1,3-dione

Thresholds in Chemical Carcinogenesis

Vehicle effects on in vitro percutaneous absorption through rat and human skin

Calculation of Benchmark Doses from Teratology Data

Empirical scoring functions. II. The testing of an empirical scoring function for the prediction of ligand-receptor binding affinities and the use of Bayesian regression to improve the quality of the model

Statistical comparison of established T-cell epitope predictors against a large database of human and murine antigens

Application of benchmark dose risk assessment methodology to developmental toxicity: an industrial view

A Physiologically Based Mathematical Model of Dermal Absorption in Man

Joint Risk from Multiple Compound Exposure

Concentration-flux relations for a multicellular biological membrane with metabolism

Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes

Pharmacokinetics of Fluazifop-butyl in Human Volunteers II: Dermal Dosing

PRO_SELECT: combining structure-based drug design and combinatorial chemistry for rapid lead discovery. 1. Technology

Human inhalation pharmacokinetics of 1,1,2-trichloro-1,2,2-trifluoroethane (FC113)

A physiologically based mathematical model for the human inhalation pharmacokinetics of 1,1,2-trichloro-1,2,2-trifluoroethane

Active immunization with angiotensin I peptide analogue vaccines selectively reduces the pressor effects of exogenous angiotensin I in conscious rats

Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine (PMD3117) in hypertensive subjects

Characterization of the interaction of 2-[2-nitro-4-(trifluoromethyl)benzoyl]-4,4,6,6,-tetramethyl- cyclohexane-1,3,5-trione with rat hepatic 4-hydroxyphenylpyruvate dioxygenase

The Predictive Accuracy of in Vitro Measurements for the Dermal Absorption of a Lipophilic Penetrant (Fluazifop-Butyl) through Rat and Human Skin

Modelling Dermal Pharmacokinetics Using in vitro Data. Part II. Fluazifop-butyl in Man

Design of active analogues of a 15-residue peptide using D-optimal design, QSAR and a combinatorial search algorithm

Modelling Dermal Pharmacokinetics Using in vitro Data Part I. Fluazifop-butyl in the Rat

Human inhalation pharmacokinetics of chlorodifluoromethane (HCFC22)

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