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Structure-based identification of OATP1B1/3 inhibitors

Molecular pharmacology, 2013-06, Vol.83 (6), p.1257-1267

2013

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Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes

European journal of pharmaceutical sciences, 2011-07, Vol.43 (4), p.297-307

2011

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In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats

Drug metabolism and disposition, 2010-10, Vol.38 (10), p.1848

2010

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Clearance Prediction of HIV Protease Inhibitors in Man: Role of Hepatic Uptake

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.854-863

2016

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Hepatic Clearance Prediction of Nine Human Immunodeficiency Virus Protease Inhibitors in Rat

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.846-853

2016

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HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect

Antiviral research, 2022-06, Vol.202, p.105311-105311, Article 105311

2022

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Higher clearance of micafungin in neonates compared with adults: role of age-dependent micafungin serum binding

Biopharmaceutics & drug disposition, 2011-05, Vol.32 (4), p.222-232

2011

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Hydration Changes Implicated in the Remarkable Temperature-Dependent Membrane Permeation of Cyclosporin A

Biochemistry (Easton), 2000-06, Vol.39 (25), p.7621-7630

2000

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Higher clearance of micafungin in neonates compared to adults: role of age-dependent micafungin serum binding

Biopharmaceutics & drug disposition, 2011-03, Vol.32 (4), p.222-232

2011

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Hepatic Clearance Prediction of Nine Human Immunodeficiency Virus Protease Inhibitors in Rat: Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.846-853

2016

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Clearance Prediction of HIV Protease Inhibitors in Man: Role of Hepatic Uptake: Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.854-863

2016

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Evidence for a Polarized Efflux System in Caco-2 Cells Capable of Modulating Cyclosporine A Transport

Biochemical and biophysical research communications, 1993-12, Vol.197 (2), p.360-365

1993

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Use of Caco-2 cells and LC/MS/MS to screen a peptide combinatorial library for permeable structures

International journal of pharmaceutics, 1999-01, Vol.177 (1), p.103-115

1999

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In vivo assessment of intestinal, hepatic, and pulmonary first pass metabolism of propofol in the rat

Pharmaceutical research, 1996-06, Vol.13 (6), p.891-895

1996

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Peptidyl Dipeptidase A-Catalyzed Metabolism of Delta Sleep-Inducing Peptide in Bovine Brain Microvessel Endothelial Cells: A Cell Culture Model of the Blood-Brain Barrier

Biochemical and biophysical research communications, 1995-05, Vol.210 (3), p.987-994

1995

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Favipiravir at high doses has potent antiviral activity in SARS-CoV-2–infected hamsters, whereas hydroxychloroquine lacks activity

Proceedings of the National Academy of Sciences - PNAS, 2020-10, Vol.117 (43), p.26955-26965

2020

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The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model

EBioMedicine, 2021-10, Vol.72, p.103595-103595, Article 103595

2021

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Challenges in Permeability Assessment for Oral Drug Product Development

Pharmaceutics, 2023-09, Vol.15 (10), p.2397

2023

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GRIN2A-related disorders: genotype and functional consequence predict phenotype

Brain (London, England : 1878), 2019-01, Vol.142 (1), p.80-92

2019

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Microcrystalline cellulose, a useful alternative for sucrose as a matrix former during freeze-drying of drug nanosuspensions – A case study with itraconazole

European journal of pharmaceutics and biopharmaceutics, 2008-10, Vol.70 (2), p.590-596

2008

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Association Between Luminal Bile Salt Content and Duodenal Mucosal Integrity in Funcional Dyspepsia

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S167-S167

2017

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Intraluminal drug and formulation behavior and integration in in vitro permeability estimation: A case study with amprenavir

Journal of pharmaceutical sciences, 2006-02, Vol.95 (2), p.372-383

2006

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Tu1760 DUODENAL BILE SALTS AND MUCOSAL CHANGES ARE LINKED WITH GASTRIC EMPTYING AND SYMPTOMS IN FUNCTIONAL DYSPEPSIA PATIENTS

Gastroenterology (New York, N.Y. 1943), 2020-05, Vol.158 (6), p.S-1149-S-1149

2020

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778b - Association Between Luminal Bile Salt Content and Duodenal Mucosal Integrity in Funcional Dyspepsia

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S167-S167

2017

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Codeine delays gastric emptying through inhibition of gastric motility as assessed with a novel diagnostic intragastric balloon catheter

Neurogastroenterology and motility, 2020-01, Vol.32 (1), p.e13733-n/a

2020

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Structure-based identification of OATP1B1/3 inhibitors

Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes

In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats

Clearance Prediction of HIV Protease Inhibitors in Man: Role of Hepatic Uptake

Hepatic Clearance Prediction of Nine Human Immunodeficiency Virus Protease Inhibitors in Rat

HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect

Higher clearance of micafungin in neonates compared with adults: role of age-dependent micafungin serum binding

Hydration Changes Implicated in the Remarkable Temperature-Dependent Membrane Permeation of Cyclosporin A

Higher clearance of micafungin in neonates compared to adults: role of age-dependent micafungin serum binding

Hepatic Clearance Prediction of Nine Human Immunodeficiency Virus Protease Inhibitors in Rat: Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism

Clearance Prediction of HIV Protease Inhibitors in Man: Role of Hepatic Uptake: Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism

Evidence for a Polarized Efflux System in Caco-2 Cells Capable of Modulating Cyclosporine A Transport

Use of Caco-2 cells and LC/MS/MS to screen a peptide combinatorial library for permeable structures

In vivo assessment of intestinal, hepatic, and pulmonary first pass metabolism of propofol in the rat

Peptidyl Dipeptidase A-Catalyzed Metabolism of Delta Sleep-Inducing Peptide in Bovine Brain Microvessel Endothelial Cells: A Cell Culture Model of the Blood-Brain Barrier

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2–infected hamsters, whereas hydroxychloroquine lacks activity

The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model

Challenges in Permeability Assessment for Oral Drug Product Development

GRIN2A-related disorders: genotype and functional consequence predict phenotype

Microcrystalline cellulose, a useful alternative for sucrose as a matrix former during freeze-drying of drug nanosuspensions – A case study with itraconazole

Association Between Luminal Bile Salt Content and Duodenal Mucosal Integrity in Funcional Dyspepsia

Intraluminal drug and formulation behavior and integration in in vitro permeability estimation: A case study with amprenavir

Tu1760 DUODENAL BILE SALTS AND MUCOSAL CHANGES ARE LINKED WITH GASTRIC EMPTYING AND SYMPTOMS IN FUNCTIONAL DYSPEPSIA PATIENTS

778b - Association Between Luminal Bile Salt Content and Duodenal Mucosal Integrity in Funcional Dyspepsia

Codeine delays gastric emptying through inhibition of gastric motility as assessed with a novel diagnostic intragastric balloon catheter

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