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Ultrathroughput immunomagnetic cell sorting platform

Lab on a chip, 2022-12, Vol.22 (24), p.4822-483

2022

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Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (9), p.3528-3533

2012

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Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions

Human molecular genetics, 2014-05, Vol.23 (9), p.2324-2338

2014

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High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

Nature biomedical engineering, 2019-10, Vol.3 (10), p.796-805

2019

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Huntingtin's spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function

eLife, 2016-03, Vol.5, p.e11184-e11184

2016

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Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

Human molecular genetics, 2011-05, Vol.20 (10), p.1937-1951

2011

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Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

Human molecular genetics, 2007-11, Vol.16 (21), p.2600-2615

2007

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Phage-Based Profiling of Rare Single Cells Using Nanoparticle-Directed Capture

ACS nano, 2021-12, Vol.15 (12), p.19202-19210

2021

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A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy

Autophagy, 2008-01, Vol.4 (1), p.91-93

2008

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Nanostructured Architectures for Biomolecular Detection inside and outside the Cell

Advanced functional materials, 2020-09, Vol.30 (37), p.n/a

2020

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Kinase inhibitors modulate huntingtin cell localization and toxicity

Nature chemical biology, 2011-05, Vol.7 (7), p.453-460

2011

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Huntington's disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases

The FEBS journal, 2008-09, Vol.275 (17), p.4252-4262

2008

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nuPRISM: Microfluidic Genome-Wide Phenotypic Screening Platform for Cellular Nuclei

ACS central science, 2022-12, Vol.8 (12), p.1618-1626

2022

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Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein

The Journal of biological chemistry, 2012-11, Vol.287 (47), p.39626-39633

2012

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Rapid On-Cell Selection of High-Performance Human Antibodies

ACS central science, 2022-01, Vol.8 (1), p.102-109

2022

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Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease

Progress in neurobiology, 2007-11, Vol.83 (4), p.211-227

2007

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Genome-wide in vivo screen of circulating tumor cells identifies SLIT2 as a regulator of metastasis

Science advances, 2022-09, Vol.8 (35), p.eabo7792-eabo7792

2022

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Hypothesis: Huntingtin may function in membrane association and vesicular trafficking

Biochemistry and cell biology, 2006-12, Vol.84 (6), p.912

2006

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Arylcyclopropanecarboxyl Guanidines as Novel, Potent, and Selective Inhibitors of the Sodium Hydrogen Exchanger Isoform-1

Journal of medicinal chemistry, 2001-09, Vol.44 (20), p.3302-3310

2001

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Hypothesis: huntingtin may function in membrane association and vesicular traffickingThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Membrane Proteins in Health and Disease

Biochemistry and cell biology, 2006-12, Vol.84 (6), p.912-917

2006

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Canadian Association of Neurosciences Review: polyglutamine expansion neurodegenerative diseases

Canadian journal of neurological sciences, 2006-08, Vol.33 (3), p.278-291

2006

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Ultrathroughput immunomagnetic cell sorting platform

Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions

High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

Huntingtin's spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function

Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

Phage-Based Profiling of Rare Single Cells Using Nanoparticle-Directed Capture

A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy

Nanostructured Architectures for Biomolecular Detection inside and outside the Cell

Kinase inhibitors modulate huntingtin cell localization and toxicity

Huntington's disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases

nuPRISM: Microfluidic Genome-Wide Phenotypic Screening Platform for Cellular Nuclei

Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein

Rapid On-Cell Selection of High-Performance Human Antibodies

Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease

Genome-wide in vivo screen of circulating tumor cells identifies SLIT2 as a regulator of metastasis

Hypothesis: Huntingtin may function in membrane association and vesicular trafficking

Arylcyclopropanecarboxyl Guanidines as Novel, Potent, and Selective Inhibitors of the Sodium Hydrogen Exchanger Isoform-1

Hypothesis: huntingtin may function in membrane association and vesicular traffickingThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Membrane Proteins in Health and Disease

Canadian Association of Neurosciences Review: polyglutamine expansion neurodegenerative diseases

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