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Ultrathroughput immunomagnetic cell sorting platform

Lab on a chip, 2022-12, Vol.22 (24), p.4822-483

2022

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Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (9), p.3528-3533

2012

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Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

Human molecular genetics, 2007-11, Vol.16 (21), p.2600-2615

2007

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Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

Human molecular genetics, 2011-05, Vol.20 (10), p.1937-1951

2011

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Huntingtin's spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function

eLife, 2016-03, Vol.5, p.e11184-e11184

2016

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Phage-Based Profiling of Rare Single Cells Using Nanoparticle-Directed Capture

ACS nano, 2021-12, Vol.15 (12), p.19202-19210

2021

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Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions

Human molecular genetics, 2014-05, Vol.23 (9), p.2324-2338

2014

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High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

Nature biomedical engineering, 2019-10, Vol.3 (10), p.796

2019

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A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy

Autophagy, 2008-01, Vol.4 (1), p.91-93

2008

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Rapid On-Cell Selection of High-Performance Human Antibodies

ACS central science, 2022-01, Vol.8 (1), p.102-109

2022

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Huntington's disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases

The FEBS journal, 2008-09, Vol.275 (17), p.4252-4262

2008

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nuPRISM: Microfluidic Genome-Wide Phenotypic Screening Platform for Cellular Nuclei

ACS central science, 2022-12, Vol.8 (12), p.1618-1626

2022

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Nanostructured Architectures for Biomolecular Detection inside and outside the Cell

Advanced functional materials, 2020-09, Vol.30 (37), p.n/a

2020

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Kinase inhibitors modulate huntingtin cell localization and toxicity

Nature chemical biology, 2011-05, Vol.7 (7), p.453

2011

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Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein

The Journal of biological chemistry, 2012-11, Vol.287 (47), p.39626-39633

2012

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Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease

Progress in neurobiology, 2007-11, Vol.83 (4), p.211-227

2007

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Hypothesis: Huntingtin may function in membrane association and vesicular trafficking

Biochemistry and cell biology, 2006-12, Vol.84 (6), p.912

2006

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Genome-wide in vivo screen of circulating tumor cells identifies SLIT2 as a regulator of metastasis

Science advances, 2022-09, Vol.8 (35), p.eabo7792-eabo7792

2022

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Canadian Association of Neurosciences Review: polyglutamine expansion neurodegenerative diseases

Canadian journal of neurological sciences, 2006-08, Vol.33 (3), p.278

2006

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Arylcyclopropanecarboxyl Guanidines as Novel, Potent, and Selective Inhibitors of the Sodium Hydrogen Exchanger Isoform-1

Journal of medicinal chemistry, 2001-09, Vol.44 (20), p.3302-3310

2001

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Ultrathroughput immunomagnetic cell sorting platform

Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

Huntingtin's spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function

Phage-Based Profiling of Rare Single Cells Using Nanoparticle-Directed Capture

Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions

High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy

Rapid On-Cell Selection of High-Performance Human Antibodies

Huntington's disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases

nuPRISM: Microfluidic Genome-Wide Phenotypic Screening Platform for Cellular Nuclei

Nanostructured Architectures for Biomolecular Detection inside and outside the Cell

Kinase inhibitors modulate huntingtin cell localization and toxicity

Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein

Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease

Hypothesis: Huntingtin may function in membrane association and vesicular trafficking

Genome-wide in vivo screen of circulating tumor cells identifies SLIT2 as a regulator of metastasis

Canadian Association of Neurosciences Review: polyglutamine expansion neurodegenerative diseases

Arylcyclopropanecarboxyl Guanidines as Novel, Potent, and Selective Inhibitors of the Sodium Hydrogen Exchanger Isoform-1

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