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Structure and closure of connexin gap junction channels

FEBS letters, 2014-04, Vol.588 (8), p.1230-1237

Oshima, Atsunori

2014

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Atomic structure of the innexin-6 gap junction channel determined by cryo-EM

Nature communications, 2016-12, Vol.7 (1), p.13681-13681, Article 13681

2016

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Structure of an innexin gap junction channel and cryo-EM sample preparation

Microscopy, 2017-12, Vol.66 (6), p.371-379

Oshima, Atsunori

2017

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Gastric proton pump with two occluded K+ engineered with sodium pump-mimetic mutations

Nature communications, 2021-09, Vol.12 (1), p.5709-5709, Article 5709

2021

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Structure of the connexin 26 gap junction channel at 3.5 Å resolution

Nature (London), 2009-04, Vol.458 (7238), p.597-602

2009

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The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel

Nature communications, 2023-07, Vol.14 (1), p.4236-4236, Article 4236

2023

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Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2

The Journal of biological chemistry, 2022-01, Vol.298 (1), p.101498-101498, Article 101498

2022

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Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding

Nature communications, 2023-09, Vol.14 (1), p.5899-5899, Article 5899

2023

Volltextzugriff (PDF)

GraDeR: Membrane Protein Complex Preparation for Single-Particle Cryo-EM

Structure (London), 2015-09, Vol.23 (9), p.1769-1775

2015

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Structure and function of H+/K+ pump mutants reveal Na+/K+ pump mechanisms

Nature communications, 2022-09, Vol.13 (1), p.5270-5270, Article 5270

2022

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Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids

Science signaling, 2022-02, Vol.15 (720), p.eabg6941

2022

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Presence of intrinsically disordered proteins can inhibit the nucleation phase of amyloid fibril formation of Aβ(1-42) in amino acid sequence independent manner

Scientific reports, 2020-07, Vol.10 (1), p.12334-12334, Article 12334

2020

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Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump

Journal of medicinal chemistry, 2022-06, Vol.65 (11), p.7843-7853

2022

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Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit

Journal of molecular biology, 2023-05, Vol.435 (10), p.168049-168049, Article 168049

2023

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Structural insights into gap junction channels boosted by cryo-EM

Current opinion in structural biology, 2020-08, Vol.63, p.42-48

Oshima, Atsunori

2020

Volltextzugriff (PDF)

Oligomeric Structure and Functional Characterization of Caenorhabditis elegans Innexin-6 Gap Junction Protein

The Journal of biological chemistry, 2013-04, Vol.288 (15), p.10513-10521

2013

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Three-dimensional structure of a human connexin26 gap junction channel reveals a plug in the vestibule

Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (24), p.10034-10039

2007

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Potential of cryo-EM for high-resolution structural analysis of gap junction channels

Current opinion in structural biology, 2019-02, Vol.54, p.78-85

Oshima, Atsunori

2019

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Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids

Science advances, 2020-02, Vol.6 (7), p.eaax3157

2020

Volltextzugriff (PDF)

Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM

Communications biology, 2022-07, Vol.5 (1), p.707-707, Article 707

2022

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A cryptic phosphate-binding pocket on the SPFH domain of human stomatin that regulates a novel fibril-like self-assembly

Current research in structural biology, 2022-01, Vol.4, p.158-166

2022

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Asymmetric Configurations and N-terminal Rearrangements in Connexin26 Gap Junction Channels

Journal of molecular biology, 2011-01, Vol.405 (3), p.724-735

2011

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Two-Dimensional Kinetics of Inter-Connexin Interactions from Single-Molecule Force Spectroscopy

Journal of molecular biology, 2011-09, Vol.412 (1), p.72-79

2011

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The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes

Journal of structural biology, 2009-10, Vol.168 (1), p.168-176

2009

Volltextzugriff (PDF)

Hexadecameric structure of an invertebrate gap junction channel

Journal of molecular biology, 2016-03, Vol.428 (6), p.1227-1236

2016

Volltextzugriff (PDF)

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Structure and closure of connexin gap junction channels

Atomic structure of the innexin-6 gap junction channel determined by cryo-EM

Structure of an innexin gap junction channel and cryo-EM sample preparation

Gastric proton pump with two occluded K+ engineered with sodium pump-mimetic mutations

Structure of the connexin 26 gap junction channel at 3.5 Å resolution

The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel

Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2

Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding

GraDeR: Membrane Protein Complex Preparation for Single-Particle Cryo-EM

Structure and function of H+/K+ pump mutants reveal Na+/K+ pump mechanisms

Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids

Presence of intrinsically disordered proteins can inhibit the nucleation phase of amyloid fibril formation of Aβ(1-42) in amino acid sequence independent manner

Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump

Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit

Structural insights into gap junction channels boosted by cryo-EM

Oligomeric Structure and Functional Characterization of Caenorhabditis elegans Innexin-6 Gap Junction Protein

Three-dimensional structure of a human connexin26 gap junction channel reveals a plug in the vestibule

Potential of cryo-EM for high-resolution structural analysis of gap junction channels

Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids

Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM

A cryptic phosphate-binding pocket on the SPFH domain of human stomatin that regulates a novel fibril-like self-assembly

Asymmetric Configurations and N-terminal Rearrangements in Connexin26 Gap Junction Channels

Two-Dimensional Kinetics of Inter-Connexin Interactions from Single-Molecule Force Spectroscopy

The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes

Hexadecameric structure of an invertebrate gap junction channel

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