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Inhibition of atypical protein kinase C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade

International journal of oncology, 2018-11, Vol.53 (5), p.1836-1846

2018

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Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors

Cell adhesion & migration, 2018-09, Vol.12 (5), p.447-463

2018

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Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis

International journal of oncology, 2017-11, Vol.51 (5), p.1370-1382

2017

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Insulin Promotes Neuronal Survival via the Alternatively Spliced Protein Kinase CδII Isoform

The Journal of biological chemistry, 2012-03, Vol.287 (12), p.9299-9310

2012

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Control of β-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-λ/ι and Nuclear Factor κ-B

Current Alzheimer research, 2021-01, Vol.18 (12), p.941

2021

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Abstract 5204: ICAM-1 and IL-17E upregulate FOXO1 to suppress the expression of oncogenic PKC-ι in human melanoma

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.5204-5204

2019

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Abstract 2022: Oncogenic protein kinase Cι drives melanoma cell epithelial-mesenchymal transition by activating vimentin through Par6/RhoA signaling

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2022-2022

2018

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Protein kinase C δ (PKCδ) splice variants modulate apoptosis pathway in 3T3L1 cells during adipogenesis: identification of PKCδII inhibitor

The Journal of biological chemistry, 2013-09, Vol.288 (37), p.26834-26846

2013

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Vitamin A Metabolite, All-trans-retinoic Acid, Mediates Alternative Splicing of Protein Kinase C δVIII (PKCδVIII) Isoform via Splicing Factor SC35

The Journal of biological chemistry, 2010-08, Vol.285 (34), p.25987-25995

2010

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Analysis of PKC-ζ protein levels in normal and malignant breast tissue subtypes

Oncology letters, 2019-02, Vol.17 (2), p.1537-1546

2019

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Identification of a novel antiapoptotic human protein kinase C delta isoform, PKCdeltaVIII in NT2 cells

Biochemistry (Easton), 2008-01, Vol.47 (2), p.787-797

2008

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Identification of a Novel Antiapoptotic Human Protein Kinase C δ Isoform, PKCδVIII in NT2 Cells

Biochemistry (Easton), 2008-01, Vol.47 (2), p.787-797

2008

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Abstract 179: Atypical protein kinase C inhibition in prostate cancer cells: a study of ICA-1 and ACPD

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.179-179

Apostolatos, Andre H.

2016

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Abstract 5868: Preclinical testing of 5-amino-1-((1R,2S,3S,4R)-2,3-dihydroxy-4-methylcyclopentyl)-1H-imidazole-4-carboxamide (ICA-1): A potent protein kinase C-ι inhibitor as a potential anticancer drug

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5868-5868

2018

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Abstract 2542: c-Jun and FOXO1 play key roles in the overexpression of oncogenic PKC-ι in human prostate and melanoma cell lines

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2542-2542

2018

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Abstract 3470: Atypical protein kinase C inhibition in prostate cancer cells: A study of ICA-1 and ACPD

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.3470-3470

2015

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Protein Kinase C δ (PKCδ) Splice Variants Modulate Apoptosis Pathway in 3T3L1 Cells during Adipogenesis

The Journal of biological chemistry, 2013-09, Vol.288 (37), p.26834-26846

2013

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Atypical PKC controls β-secretase expression and thereby regulates production of Alzheimer plaque precursor Aβ in brain and insulin receptor degradation in liver

Metabolism, clinical and experimental, 2020-03, Vol.104, p.154112, Article 154112

2020

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Analysis of PKC- protein levels in normal and malignant breast tissue subtypes

Oncology letters, 2019-02, Vol.17 (2), p.1537

2019

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Abstract 2369: Transcription activators that regulate PKC-iota expression and are downstream targets of PKC-iota

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2369-2369

2017

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FOXO1 regulates oncogenic PKC-[iota] expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation

World Academy of Sciences Journal, 2019-01, p.25

2019

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The Effect of Cinnamon on Adipogenesis: 2171

The American journal of gastroenterology, 2014-10, Vol.109, p.S629

2014

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Protein kinase C delta (PKCδ) splice variant modulates senescence via hTERT in adipose-derived stem cells

Stem cell investigation, 2014, Vol.1, p.3-3

2014

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Dysregulated Alternative Splicing Pattern of PKCδ during Differentiation of Human Preadipocytes Represents Distinct Differences between Lean and Obese Adipocytes

ISRN obesity, 2013-04, Vol.2013, p.161345-9

2013

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Alternative splicing of key survival genes during adipogenesis

The FASEB journal, 2012-04, Vol.26 (S1)

2012

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Inhibition of atypical protein kinase C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade

Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors

Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis

Insulin Promotes Neuronal Survival via the Alternatively Spliced Protein Kinase CδII Isoform

Control of β-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-λ/ι and Nuclear Factor κ-B

Abstract 5204: ICAM-1 and IL-17E upregulate FOXO1 to suppress the expression of oncogenic PKC-ι in human melanoma

Abstract 2022: Oncogenic protein kinase Cι drives melanoma cell epithelial-mesenchymal transition by activating vimentin through Par6/RhoA signaling

Protein kinase C δ (PKCδ) splice variants modulate apoptosis pathway in 3T3L1 cells during adipogenesis: identification of PKCδII inhibitor

Vitamin A Metabolite, All-trans-retinoic Acid, Mediates Alternative Splicing of Protein Kinase C δVIII (PKCδVIII) Isoform via Splicing Factor SC35

Analysis of PKC-ζ protein levels in normal and malignant breast tissue subtypes

Identification of a novel antiapoptotic human protein kinase C delta isoform, PKCdeltaVIII in NT2 cells

Identification of a Novel Antiapoptotic Human Protein Kinase C δ Isoform, PKCδVIII in NT2 Cells

Abstract 179: Atypical protein kinase C inhibition in prostate cancer cells: a study of ICA-1 and ACPD

Abstract 5868: Preclinical testing of 5-amino-1-((1R,2S,3S,4R)-2,3-dihydroxy-4-methylcyclopentyl)-1H-imidazole-4-carboxamide (ICA-1): A potent protein kinase C-ι inhibitor as a potential anticancer drug

Abstract 2542: c-Jun and FOXO1 play key roles in the overexpression of oncogenic PKC-ι in human prostate and melanoma cell lines

Abstract 3470: Atypical protein kinase C inhibition in prostate cancer cells: A study of ICA-1 and ACPD

Protein Kinase C δ (PKCδ) Splice Variants Modulate Apoptosis Pathway in 3T3L1 Cells during Adipogenesis

Atypical PKC controls β-secretase expression and thereby regulates production of Alzheimer plaque precursor Aβ in brain and insulin receptor degradation in liver

Analysis of PKC- protein levels in normal and malignant breast tissue subtypes

Abstract 2369: Transcription activators that regulate PKC-iota expression and are downstream targets of PKC-iota

FOXO1 regulates oncogenic PKC-[iota] expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation

The Effect of Cinnamon on Adipogenesis: 2171

Protein kinase C delta (PKCδ) splice variant modulates senescence via hTERT in adipose-derived stem cells

Dysregulated Alternative Splicing Pattern of PKCδ during Differentiation of Human Preadipocytes Represents Distinct Differences between Lean and Obese Adipocytes

Alternative splicing of key survival genes during adipogenesis

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