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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

PLoS computational biology, 2019-01, Vol.15 (1), p.e1006774-e1006774

2019

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Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

Science (American Association for the Advancement of Science), 2012-01, Vol.335 (6064), p.100-104

2012

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Tools to develop antibiotic combinations that target drug tolerance in Mycobacterium tuberculosis

Frontiers in cellular and infection microbiology, 2023-01, Vol.12, p.1085946-1085946

2023

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Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection

PLoS pathogens, 2014-09, Vol.10 (9), p.e1004394

2014

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Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis

mBio, 2019-11, Vol.10 (6)

2019

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Stable Regulation of Cell Cycle Events in Mycobacteria: Insights From Inherently Heterogeneous Bacterial Populations

Frontiers in microbiology, 2018-03, Vol.9, p.514-514

2018

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Temporal and intrinsic factors of rifampicin tolerance in mycobacteria

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (29), p.8302-8307

2016

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Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

Molecular cell, 2008-04, Vol.30 (1), p.11-25

2008

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Morphological profiling of tubercle bacilli identifies drug pathways of action

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (31), p.18744-18753

2020

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Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses

mBio, 2024-02, Vol.15 (3), p.e0015924-e0015924

2024

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Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling

PLoS computational biology, 2009-04, Vol.5 (4), p.e1000340-e1000340

2009

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Localization of EccA3 at the growing pole in Mycobacterium smegmatis

BMC microbiology, 2022-05, Vol.22 (1), p.1-140, Article 140

2022

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Rv0004 is a new essential member of the mycobacterial DNA replication machinery

PLoS genetics, 2017-11, Vol.13 (11), p.e1007115-e1007115

2017

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Stress-Induced Reorganization of the Mycobacterial Membrane Domain

mBio, 2018-01, Vol.9 (1)

2018

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Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria

PLoS pathogens, 2013-02, Vol.9 (2), p.e1003197-e1003197

2013

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Types and functions of heterogeneity in mycobacteria

Nature reviews. Microbiology, 2022-09, Vol.20 (9), p.529-541

2022

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Influence of Stress and Antibiotic Resistance on Cell-Length Distribution in Mycobacterium tuberculosis Clinical Isolates

Frontiers in microbiology, 2017-11, Vol.8, p.2296-2296

2017

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Engineered cell and tissue models of pulmonary fibrosis

Advanced drug delivery reviews, 2018-04, Vol.129, p.78-94

2018

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Semi-automated colony-forming unit counting for biosafety level 3 laboratories

STAR protocols, 2023-09, Vol.4 (3), p.102442-102442, Article 102442

2023

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Advances in the design of combination therapies for the treatment of tuberculosis

Expert opinion on drug discovery, 2023-01, Vol.18 (1), p.83-97

2023

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Leveraging laboratory and clinical studies to design effective antibiotic combination therapy

Current opinion in microbiology, 2021-12, Vol.64, p.68-75

2021

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Multiscale Model Identifies Improved Schedule for Treatment of Acute Myeloid Leukemia In Vitro With the Mcl‐1 Inhibitor AZD5991

CPT: pharmacometrics and systems pharmacology, 2020-10, Vol.9 (10), p.561-570

2020

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Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis

Science advances, 2017-10, Vol.3 (10), p.e1701881-e1701881

2017

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Microbial metabolomics: innovation, application, insight

Current opinion in microbiology, 2014-06, Vol.19, p.90-96

2014

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Targeting drugs for tuberculosis

Science (American Association for the Advancement of Science), 2019-06, Vol.364 (6447), p.1234-1235

2019

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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

Tools to develop antibiotic combinations that target drug tolerance in Mycobacterium tuberculosis

Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection

Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis

Stable Regulation of Cell Cycle Events in Mycobacteria: Insights From Inherently Heterogeneous Bacterial Populations

Temporal and intrinsic factors of rifampicin tolerance in mycobacteria

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

Morphological profiling of tubercle bacilli identifies drug pathways of action

Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses

Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling

Localization of EccA3 at the growing pole in Mycobacterium smegmatis

Rv0004 is a new essential member of the mycobacterial DNA replication machinery

Stress-Induced Reorganization of the Mycobacterial Membrane Domain

Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria

Types and functions of heterogeneity in mycobacteria

Influence of Stress and Antibiotic Resistance on Cell-Length Distribution in Mycobacterium tuberculosis Clinical Isolates

Engineered cell and tissue models of pulmonary fibrosis

Semi-automated colony-forming unit counting for biosafety level 3 laboratories

Advances in the design of combination therapies for the treatment of tuberculosis

Leveraging laboratory and clinical studies to design effective antibiotic combination therapy

Multiscale Model Identifies Improved Schedule for Treatment of Acute Myeloid Leukemia In Vitro With the Mcl‐1 Inhibitor AZD5991

Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis

Microbial metabolomics: innovation, application, insight

Targeting drugs for tuberculosis

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