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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

PLoS computational biology, 2019-01, Vol.15 (1), p.e1006774-e1006774

2019

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Definitions and guidelines for research on antibiotic persistence

Nature reviews. Microbiology, 2019-07, Vol.17 (7), p.441-448

2019

Volltextzugriff (PDF)

Types and functions of heterogeneity in mycobacteria

Nature reviews. Microbiology, 2022-09, Vol.20 (9), p.529-541

2022

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Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection

PLoS pathogens, 2014-09, Vol.10 (9), p.e1004394

2014

Volltextzugriff (PDF)

Tools to develop antibiotic combinations that target drug tolerance in Mycobacterium tuberculosis

Frontiers in cellular and infection microbiology, 2023-01, Vol.12, p.1085946-1085946

2023

Volltextzugriff (PDF)

Engineered cell and tissue models of pulmonary fibrosis

Advanced drug delivery reviews, 2018-04, Vol.129, p.78-94

2018

Volltextzugriff (PDF)

Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

Science (American Association for the Advancement of Science), 2012-01, Vol.335 (6064), p.100-104

2012

Volltextzugriff (PDF)

Advances in the design of combination therapies for the treatment of tuberculosis

Expert opinion on drug discovery, 2023-01, Vol.18 (1), p.83-97

2023

Volltextzugriff (PDF)

Leveraging laboratory and clinical studies to design effective antibiotic combination therapy

Current opinion in microbiology, 2021-12, Vol.64, p.68-75

2021

Volltextzugriff (PDF)

Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling

Cell chemical biology, 2022-05, Vol.29 (5), p.883-896.e5

2022

Volltextzugriff (PDF)

Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis

Science advances, 2017-10, Vol.3 (10), p.e1701881-e1701881

2017

Volltextzugriff (PDF)

Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis

mBio, 2019-11, Vol.10 (6)

2019

Volltextzugriff (PDF)

Stable Regulation of Cell Cycle Events in Mycobacteria: Insights From Inherently Heterogeneous Bacterial Populations

Frontiers in microbiology, 2018-03, Vol.9, p.514-514

2018

Volltextzugriff (PDF)

Microbial metabolomics: innovation, application, insight

Current opinion in microbiology, 2014-06, Vol.19, p.90-96

2014

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Temporal and intrinsic factors of rifampicin tolerance in mycobacteria

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (29), p.8302-8307

2016

Volltextzugriff (PDF)

Targeting drugs for tuberculosis

Science (American Association for the Advancement of Science), 2019-06, Vol.364 (6447), p.1234-1235

2019

Volltextzugriff (PDF)

Physicochemical modelling of cell signalling pathways

Nature cell biology, 2006-11, Vol.8 (11), p.1195-1203

2006

Volltextzugriff (PDF)

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

Molecular cell, 2008-04, Vol.30 (1), p.11-25

2008

Volltextzugriff (PDF)

Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling

PLoS computational biology, 2009-04, Vol.5 (4), p.e1000340-e1000340

2009

Volltextzugriff (PDF)

Morphological profiling of tubercle bacilli identifies drug pathways of action

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (31), p.18744-18753

2020

Volltextzugriff (PDF)

Tuberculosis treatment failure associated with evolution of antibiotic resilience

Science (American Association for the Advancement of Science), 2022-12, Vol.378 (6624), p.1111-1118

2022

Volltextzugriff (PDF)

A Parallel Adder Coordinates Mycobacterial Cell-Cycle Progression and Cell-Size Homeostasis in the Context of Asymmetric Growth and Organization

Current biology, 2017-11, Vol.27 (21), p.3367-3374.e7

2017

Volltextzugriff (PDF)

Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses

mBio, 2024-03, Vol.15 (3), p.e0015924-e0015924

2024

Volltextzugriff (PDF)

In vitro identification of underutilized β-lactam combinations against methicillin-resistant Staphylococcus aureus bacteremia isolates

Microbiology spectrum, 2024-08, Vol.12 (8), p.e0097624

2024

Volltextzugriff (PDF)

Design principles to assemble drug combinations for effective tuberculosis therapy using interpretable pairwise drug response measurements

Cell reports. Medicine, 2022-09, Vol.3 (9), p.100737, Article 100737

2022

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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

Definitions and guidelines for research on antibiotic persistence

Types and functions of heterogeneity in mycobacteria

Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection

Tools to develop antibiotic combinations that target drug tolerance in Mycobacterium tuberculosis

Engineered cell and tissue models of pulmonary fibrosis

Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

Advances in the design of combination therapies for the treatment of tuberculosis

Leveraging laboratory and clinical studies to design effective antibiotic combination therapy

Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling

Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis

Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis

Stable Regulation of Cell Cycle Events in Mycobacteria: Insights From Inherently Heterogeneous Bacterial Populations

Microbial metabolomics: innovation, application, insight

Temporal and intrinsic factors of rifampicin tolerance in mycobacteria

Targeting drugs for tuberculosis

Physicochemical modelling of cell signalling pathways

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling

Morphological profiling of tubercle bacilli identifies drug pathways of action

Tuberculosis treatment failure associated with evolution of antibiotic resilience

A Parallel Adder Coordinates Mycobacterial Cell-Cycle Progression and Cell-Size Homeostasis in the Context of Asymmetric Growth and Organization

Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses

In vitro identification of underutilized β-lactam combinations against methicillin-resistant Staphylococcus aureus bacteremia isolates

Design principles to assemble drug combinations for effective tuberculosis therapy using interpretable pairwise drug response measurements

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