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Accessing protein conformational ensembles using room-temperature X-ray crystallography

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (39), p.16247-16252

2011

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Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (36), p.E636-E645

2011

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The energy landscape of adenylate kinase during catalysis

Nature structural & molecular biology, 2015-02, Vol.22 (2), p.124

2015

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Protein structural ensembles are revealed by redefining X-ray electron density noise

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (1), p.237-242

2014

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Automated Protein Crystal Structure Determination Using ELVES

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (6), p.1537-1542

2004

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Moving Metal Ions through Ferritin−Protein Nanocages from Three-Fold Pores to Catalytic Sites

Journal of the American Chemical Society, 2010-10, Vol.132 (41), p.14562-14569

2010

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Saccharomyces cerevisiae septins: Supramolecular organization of heterooligomers and the mechanism of filament assembly

Proceedings of the National Academy of Sciences - PNAS, 2008-06, Vol.105 (24), p.8274-8279

2008

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Depletion of antibiotic targets has widely varying effects on growth

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (10), p.4176-4181

2011

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Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (22), p.8037-8042

2014

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A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria

Science signaling, 2012-01, Vol.5 (208), p.ra7

2012

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Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (8), p.2978-2983

2014

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Automated electron‐density sampling reveals widespread conformational polymorphism in proteins

Protein science, 2010-07, Vol.19 (7), p.1420-1431

2010

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AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (1), p.E15-E24

2014

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HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (2), p.E123-E131

2013

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tRNA Binding, Structure, and Localization of the Human Interferon-Induced Protein IFIT5

Molecular cell, 2013-02, Vol.49 (4), p.743-750

2013

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AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter

eLife, 2014-04, Vol.3, p.e02375-e02375

2014

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Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (52), p.E5069-E5077

2013

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Hyaloperonospora arabidopsidis ATR1 effector is a repeat protein with distributed recognition surfaces

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (32), p.13323-13328

2011

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Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria

PLoS pathogens, 2013-02, Vol.9 (2), p.e1003197-e1003197

2013

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The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat

eLife, 2013-03, Vol.2, p.e00327-e00327

2013

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Hydrogen–Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling

ACS central science, 2017-06, Vol.3 (6), p.570-579

2017

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Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB Structure Reveals a Diverged Fold and a Buried Active Site

Structure (London), 2005-11, Vol.13 (11), p.1625-1634

2005

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Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity

PloS one, 2012-11, Vol.7 (11), p.e49048-e49048

2012

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Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB

Structure (London), 2007-04, Vol.15 (4), p.499-509

2007

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Diterpene production in Mycobacterium tuberculosis

The FEBS journal, 2010-09, Vol.277 (17), p.3588-3595

2010

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Accessing protein conformational ensembles using room-temperature X-ray crystallography

Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin

The energy landscape of adenylate kinase during catalysis

Protein structural ensembles are revealed by redefining X-ray electron density noise

Automated Protein Crystal Structure Determination Using ELVES

Moving Metal Ions through Ferritin−Protein Nanocages from Three-Fold Pores to Catalytic Sites

Saccharomyces cerevisiae septins: Supramolecular organization of heterooligomers and the mechanism of filament assembly

Depletion of antibiotic targets has widely varying effects on growth

Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC

A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria

Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c

Automated electron‐density sampling reveals widespread conformational polymorphism in proteins

AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation

HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold

tRNA Binding, Structure, and Localization of the Human Interferon-Induced Protein IFIT5

AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter

Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase

Hyaloperonospora arabidopsidis ATR1 effector is a repeat protein with distributed recognition surfaces

Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat

Hydrogen–Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling

Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB Structure Reveals a Diverged Fold and a Buried Active Site

Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity

Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB

Diterpene production in Mycobacterium tuberculosis

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