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Aging immunity may exacerbate COVID-19

Science (American Association for the Advancement of Science), 2020-07, Vol.369 (6501), p.256-257

2020

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Targeting Inflammation and Immunosenescence to Improve Vaccine Responses in the Elderly

Frontiers in immunology, 2020-10, Vol.11, p.583019-583019

2020

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Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition

Nature communications, 2019-06, Vol.10 (1), p.2387-2387, Article 2387

2019

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Convergence of Innate and Adaptive Immunity during Human Aging

Frontiers in immunology, 2016-11, Vol.7, p.445-445

2016

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Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5'-Monophosphate-Activated Protein Kinase

The Journal of immunology (1950), 2016-10, Vol.197 (7), p.2891-2899

2016

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Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase–induced inflammation

Journal of allergy and clinical immunology, 2018-09, Vol.142 (3), p.844-856

2018

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Post-resolution macrophages shape long-term tissue immunity and integrity in a mouse model of pneumococcal pneumonia

Nature communications, 2024-05, Vol.15 (1), p.4326-17, Article 4326

2024

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Senescence of T Lymphocytes: Implications for Enhancing Human Immunity

Trends in immunology, 2016-12, Vol.37 (12), p.866-876

2016

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Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer

Frontiers in oncology, 2023-06, Vol.13, p.1156743

2023

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GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage

Nature communications, 2021-06, Vol.12 (1), p.3379-3379, Article 3379

2021

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The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells

Nature immunology, 2014-10, Vol.15 (10), p.965-972

2014

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Upregulation of keratin 15 is required for varicella-zoster virus replication in keratinocytes and is attenuated in the live attenuated vOka vaccine strain

Virology journal, 2024-10, Vol.21 (1), p.253-11, Article 253

2024

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PD-1 Blockade Modulates Functional Activities of Exhausted-Like T Cell in Patients With Cutaneous Leishmaniasis

Frontiers in immunology, 2021-03, Vol.12, p.632667-632667

2021

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Circulating Senescent T Cells Are Linked to Systemic Inflammation and Lesion Size During Human Cutaneous Leishmaniasis

Frontiers in immunology, 2019-01, Vol.9, p.3001-3001

2019

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Are senescence and exhaustion intertwined or unrelated processes that compromise immunity?

Nature reviews. Immunology, 2011-04, Vol.11 (4), p.289-295

2011

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Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging

Nature aging, 2021-01, Vol.1 (1), p.101-113

2021

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Can blocking inflammation enhance immunity during aging?

Journal of allergy and clinical immunology, 2020-05, Vol.145 (5), p.1323-1331

2020

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CD28− T cells: their role in the age-associated decline of immune function

Trends in immunology, 2009-07, Vol.30 (7), p.306-312

2009

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Senescent T cells: Beneficial and detrimental roles

Immunological reviews, 2023-07, Vol.316 (1), p.160-175

2023

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Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation

Trends in immunology, 2001-04, Vol.22 (4), p.199-204

2001

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A sestrin-dependent Erk-Jnk-p38 MAPK activation complex inhibits immunity during aging

Nature immunology, 2017-03, Vol.18 (3), p.354-363

2017

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An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory

Nature cell biology, 2022-10, Vol.24 (10), p.1461-1474

2022

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Mitochondrial mass governs the extent of human T cell senescence

Aging cell, 2020-02, Vol.19 (2), p.e13067-n/a

2020

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p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells

The Journal of clinical investigation, 2014-09, Vol.124 (9), p.4004-4016

2014

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Aging immunity may exacerbate COVID-19

Targeting Inflammation and Immunosenescence to Improve Vaccine Responses in the Elderly

Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition

Convergence of Innate and Adaptive Immunity during Human Aging

Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5'-Monophosphate-Activated Protein Kinase

Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase–induced inflammation

Post-resolution macrophages shape long-term tissue immunity and integrity in a mouse model of pneumococcal pneumonia

Senescence of T Lymphocytes: Implications for Enhancing Human Immunity

Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer

GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage

The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells

Upregulation of keratin 15 is required for varicella-zoster virus replication in keratinocytes and is attenuated in the live attenuated vOka vaccine strain

PD-1 Blockade Modulates Functional Activities of Exhausted-Like T Cell in Patients With Cutaneous Leishmaniasis

Circulating Senescent T Cells Are Linked to Systemic Inflammation and Lesion Size During Human Cutaneous Leishmaniasis

Are senescence and exhaustion intertwined or unrelated processes that compromise immunity?

Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging

Can blocking inflammation enhance immunity during aging?

CD28− T cells: their role in the age-associated decline of immune function

Senescent T cells: Beneficial and detrimental roles

Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation

A sestrin-dependent Erk-Jnk-p38 MAPK activation complex inhibits immunity during aging

Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial

An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory

Mitochondrial mass governs the extent of human T cell senescence

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells

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