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Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886

Bioorganic & medicinal chemistry letters, 2005-07, Vol.15 (14), p.3352-3355

2005

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Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of spirocyclic piperidines

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (24), p.7399-7404

2011

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Diastereoselective Intermolecular [4 + 3] Cycloadditions via an Extended Transition State: A Route to Enantiomerically Enriched Cycloadducts

Journal of the American Chemical Society, 1996-11, Vol.118 (44), p.10930-10931

1996

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3,4-Diarylpiperidines as potent renin inhibitors

Bioorganic & medicinal chemistry letters, 2012-03, Vol.22 (5), p.1953-1957

2012

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Inhibitors of the inducible microsomal prostaglandin E 2 synthase (mPGES-1) derived from MK-886

Bioorganic & medicinal chemistry letters, 2005-07, Vol.15 (14), p.3352-3355

2005

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Identification of a new biaryl scaffold generating potent renin inhibitors

Bioorganic & medicinal chemistry letters, 2010-10, Vol.20 (19), p.5822-5826

2010

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Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment

Bioorganic & medicinal chemistry letters, 2010-11, Vol.20 (22), p.6387-6393

2010

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The discovery and synthesis of highly potent subtype selective phosphodiesterase 4D inhibitors

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (18), p.5502-5505

2010

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Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis

Journal of medicinal chemistry, 2004-05, Vol.47 (10), p.2466-2474

2004

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The discovery and synthesis of potent zwitterionic inhibitors of renin

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2430-2436

2011

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Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinones

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (6), p.1671-1674

2007

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Solid phase synthesis of selective caspase-3 peptide inhibitors

Bioorganic & medicinal chemistry, 2004-03, Vol.12 (5), p.845-851

2004

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Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase

Journal of medicinal chemistry, 2006-03, Vol.49 (6), p.1867-1873

2006

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Diastereoselective intermolecular (4+3) cycloadditions between chiral furans and oxyallyl cations: A route to enantiomerically enriched cycloadducts

Aspiotis, Renee

1997

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Discovery of novel aspartyl ketone dipeptides as potent and selective caspase-3 inhibitors

Bioorganic & medicinal chemistry letters, 2004-02, Vol.14 (3), p.805-808

2004

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Lipophilic versus hydrogen-bonding effect in P 3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors

Bioorganic & medicinal chemistry letters, 2005-09, Vol.15 (17), p.3886-3890

2005

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Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors

Bioorganic & medicinal chemistry letters, 2005-09, Vol.15 (17), p.3886-3890

2005

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Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886

Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of spirocyclic piperidines

Diastereoselective Intermolecular [4 + 3] Cycloadditions via an Extended Transition State: A Route to Enantiomerically Enriched Cycloadducts

3,4-Diarylpiperidines as potent renin inhibitors

Inhibitors of the inducible microsomal prostaglandin E 2 synthase (mPGES-1) derived from MK-886

Identification of a new biaryl scaffold generating potent renin inhibitors

Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment

The discovery and synthesis of highly potent subtype selective phosphodiesterase 4D inhibitors

Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis

The discovery and synthesis of potent zwitterionic inhibitors of renin

Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinones

Solid phase synthesis of selective caspase-3 peptide inhibitors

Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase

Diastereoselective intermolecular (4+3) cycloadditions between chiral furans and oxyallyl cations: A route to enantiomerically enriched cycloadducts

Discovery of novel aspartyl ketone dipeptides as potent and selective caspase-3 inhibitors

Lipophilic versus hydrogen-bonding effect in P 3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors

Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors

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