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A naturally occurring antiviral ribonucleotide encoded by the human genome

Nature (London), 2018-06, Vol.558 (7711), p.610-614

2018

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A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus

PLoS biology, 2018-06, Vol.16 (6), p.e2006459-e2006459

2018

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Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP

Nucleic acids research, 2022-11, Vol.50 (20), p.11775-11798

2022

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Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

Nature, 2006-01, Vol.439 (7074), p.344-348

2006

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The enterovirus genome can be translated in an IRES-independent manner that requires the initiation factors eIF2A/eIF2D

PLoS biology, 2023-01, Vol.21 (1), p.e3001693-e3001693

2023

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Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides

PLoS pathogens, 2012-11, Vol.8 (11), p.e1003030

2012

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Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics

Cell reports (Cambridge), 2017-11, Vol.21 (6), p.1692-1704

2017

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Viperin Reveals Its True Function

Annual review of virology, 2020-09, Vol.7 (1), p.421-446

2020

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Biochemical and genetic analysis of the role of the viral polymerase in enterovirus recombination

Nucleic acids research, 2016-08, Vol.44 (14), p.6883-6895

2016

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RNA Virus Population Diversity, an Optimum for Maximal Fitness and Virulence

The Journal of biological chemistry, 2014-10, Vol.289 (43), p.29531-29544

2014

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Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

eLife, 2021-10, Vol.10

2021

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The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family

PLoS pathogens, 2015-03, Vol.11 (3), p.e1004733-e1004733

2015

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Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease

Nucleic acids research, 2023-01, Vol.51 (1), p.315-336

2023

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The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

Nucleic acids research, 2010-01, Vol.38 (1), p.203-214

2010

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Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes

PLoS pathogens, 2015-06, Vol.11 (6), p.e1005009

2015

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Structure-function relationships among RNA-dependent RNA polymerases

Current topics in microbiology and immunology, 2008, Vol.320, p.137

2008

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Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers

Cell reports (Cambridge), 2017-10, Vol.21 (4), p.1063-1076

2017

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Motif D of Viral RNA-Dependent RNA Polymerases Determines Efficiency and Fidelity of Nucleotide Addition

Structure (London), 2012-09, Vol.20 (9), p.1519-1527

2012

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Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides

PLoS pathogens, 2018-04, Vol.14 (4), p.e1007036-e1007036

2018

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UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication

PLoS pathogens, 2017-05, Vol.13 (5), p.e1006375-e1006375

2017

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Determinants of RNA-Dependent RNA Polymerase (In)fidelity Revealed by Kinetic Analysis of the Polymerase Encoded by a Foot-and-Mouth Disease Virus Mutant with Reduced Sensitivity to Ribavirin

Journal of Virology, 2008-12, Vol.82 (24), p.12346-12355

2008

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Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds

PLoS pathogens, 2010-10, Vol.6 (10), p.e1001163

2010

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Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (17), p.6513-6518

2012

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A Polymerase Mechanism-based Strategy for Viral Attenuation and Vaccine Development

The Journal of biological chemistry, 2012-09, Vol.287 (38), p.31618-31622

2012

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Hepatitis C Virus Nonstructural Protein 5A (NS5A) Is an RNA-binding Protein

The Journal of biological chemistry, 2005-10, Vol.280 (43), p.36417-36428

2005

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A naturally occurring antiviral ribonucleotide encoded by the human genome

A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus

Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP

Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

The enterovirus genome can be translated in an IRES-independent manner that requires the initiation factors eIF2A/eIF2D

Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides

Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics

Viperin Reveals Its True Function

Biochemical and genetic analysis of the role of the viral polymerase in enterovirus recombination

RNA Virus Population Diversity, an Optimum for Maximal Fitness and Virulence

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family

Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease

The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes

Structure-function relationships among RNA-dependent RNA polymerases

Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers

Motif D of Viral RNA-Dependent RNA Polymerases Determines Efficiency and Fidelity of Nucleotide Addition

Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides

UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication

Determinants of RNA-Dependent RNA Polymerase (In)fidelity Revealed by Kinetic Analysis of the Polymerase Encoded by a Foot-and-Mouth Disease Virus Mutant with Reduced Sensitivity to Ribavirin

Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds

Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro

A Polymerase Mechanism-based Strategy for Viral Attenuation and Vaccine Development

Hepatitis C Virus Nonstructural Protein 5A (NS5A) Is an RNA-binding Protein

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