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Aβ Oligomer Toxicity-Reducing Therapy for the Prevention of Alzheimer's Disease: Importance of the Nrf2 and PPARγ Pathways

Cells (Basel, Switzerland), 2023-05, Vol.12 (10), p.1386

Araki, Wataru

2023

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Potential repurposing of oncology drugs for the treatment of Alzheimer's disease

BMC medicine, 2013-03, Vol.11 (1), p.82-82, Article 82

Araki, Wataru

2013

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Protection against Amyloid-β Oligomer Neurotoxicity by Small Molecules with Antioxidative Properties: Potential for the Prevention of Alzheimer's Disease Dementia

Antioxidants, 2022-01, Vol.11 (1), p.132

2022

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Amyloid beta-protein and lipid rafts focused on biogenesis and catabolism

Frontiers in bioscience, 2015-01, Vol.20 (2), p.314-324, Article 4311

Araki, Wataru

2015

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Computerized decision support is an effective approach to select memory clinic patients for amyloid-PET

PloS one, 2024-05, Vol.19 (5), p.e0303111-e0303111

2024

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A causal inference study: The impact of the combined administration of Donepezil and Memantine on decreasing hospital and emergency department visits of Alzheimer’s disease patients

PloS one, 2023-09, Vol.18 (9), p.e0291362

2023

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Amyloid-β oligomers interact with NMDA receptors containing GluN2B subunits and metabotropic glutamate receptor 1 in primary cortical neurons: Relevance to the synapse pathology of Alzheimer’s disease

Neuroscience research, 2022-07, Vol.180, p.90-98

2022

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Comparative assessment of regional tau distribution by Tau-PET and Post-mortem neuropathology in a representative set of Alzheimer's & frontotemporal lobar degeneration patients

PloS one, 2023-05, Vol.18 (5), p.e0284182

2023

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Oral nimodipine treatment has no effect on amyloid pathology or neuritic dystrophy in the 5XFAD mouse model of amyloidosis

PloS one, 2022-02, Vol.17 (2), p.e0263332-e0263332

2022

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C5aR agonist enhances phagocytosis of fibrillar and non-fibrillar Aβ amyloid and preserves memory in a mouse model of familial Alzheimer's disease

PloS one, 2019-12, Vol.14 (12), p.e0225417-e0225417

2019

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Nicotinic receptor components of amyloid beta 42 proteome regulation in human neural cells

PloS one, 2022-08, Vol.17 (8), p.e0270479-e0270479

2022

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Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE1

Journal of biochemistry (Tokyo), 2021-12, Vol.170 (6), p.729-738

2021

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Oxidative stress up-regulates presenilin 1 in lipid rafts in neuronal cells

Journal of neuroscience research, 2010-04, Vol.88 (5), p.1137-1145

2010

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Post-translational regulation of the β-secretase BACE1

Brain research bulletin, 2016-09, Vol.126 (Pt 2), p.170-177

Araki, Wataru

2016

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Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain

Journal of nanobiotechnology, 2023-01, Vol.21 (1), p.36-36, Article 36

2023

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Soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for differential diagnosis of mild cognitive impairment

Aging clinical and experimental research, 2022-02, Vol.34 (2), p.341-347

2022

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A case with burning mouth syndrome followed by dementia with Lewy bodies: a case report

Frontiers in psychiatry, 2024-01, Vol.14, p.1329171

2024

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Disease-Associated Mutations of TDP-43 Promote Turnover of the Protein Through the Proteasomal Pathway

Molecular neurobiology, 2014-12, Vol.50 (3), p.1049-1058

2014

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Potential value of soluble APPα and APPβ in CSF as biomarkers of dementia disorders: Unresolved issues and perspectives

Neurology and clinical neuroscience, 2018-07, Vol.6 (4), p.89-93

2018

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Reversibility of Aβ oligomer neurotoxicity

Oncotarget, 2017-08, Vol.8 (31), p.50335-50336

Araki, Wataru

2017

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Chronic cladribine administration increases amyloid beta peptide generation and plaque burden in mice

PloS one, 2012-10, Vol.7 (10), p.e45841

2012

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Enhanced generation of intracellular Aβ42 amyloid peptide by mutation of presenilins PS1 and PS2

The European journal of neuroscience, 2004-01, Vol.19 (2), p.258-364

2004

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Homocysteic acid induces intraneuronal accumulation of neurotoxic Aβ42: Implications for the pathogenesis of Alzheimer's disease

Journal of neuroscience research, 2005-06, Vol.80 (6), p.869-876

2005

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Amyloid beta-protein and lipid rafts: focused on biogenesis and catabolism

Frontiers in bioscience (Landmark. Print), 2015-01, Vol.20 (2), p.314

2015

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Meet Our Editorial Board Member

Current neuropharmacology, 2016-01, Vol.14 (1), p.1-1

Araki, Wataru

2016

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Aβ Oligomer Toxicity-Reducing Therapy for the Prevention of Alzheimer's Disease: Importance of the Nrf2 and PPARγ Pathways

Potential repurposing of oncology drugs for the treatment of Alzheimer's disease

Protection against Amyloid-β Oligomer Neurotoxicity by Small Molecules with Antioxidative Properties: Potential for the Prevention of Alzheimer's Disease Dementia

Amyloid beta-protein and lipid rafts focused on biogenesis and catabolism

Computerized decision support is an effective approach to select memory clinic patients for amyloid-PET

A causal inference study: The impact of the combined administration of Donepezil and Memantine on decreasing hospital and emergency department visits of Alzheimer’s disease patients

Amyloid-β oligomers interact with NMDA receptors containing GluN2B subunits and metabotropic glutamate receptor 1 in primary cortical neurons: Relevance to the synapse pathology of Alzheimer’s disease

Comparative assessment of regional tau distribution by Tau-PET and Post-mortem neuropathology in a representative set of Alzheimer's & frontotemporal lobar degeneration patients

Oral nimodipine treatment has no effect on amyloid pathology or neuritic dystrophy in the 5XFAD mouse model of amyloidosis

C5aR agonist enhances phagocytosis of fibrillar and non-fibrillar Aβ amyloid and preserves memory in a mouse model of familial Alzheimer's disease

Nicotinic receptor components of amyloid beta 42 proteome regulation in human neural cells

Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE1

Oxidative stress up-regulates presenilin 1 in lipid rafts in neuronal cells

Post-translational regulation of the β-secretase BACE1

Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain

Soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for differential diagnosis of mild cognitive impairment

A case with burning mouth syndrome followed by dementia with Lewy bodies: a case report

Disease-Associated Mutations of TDP-43 Promote Turnover of the Protein Through the Proteasomal Pathway

Potential value of soluble APPα and APPβ in CSF as biomarkers of dementia disorders: Unresolved issues and perspectives

Reversibility of Aβ oligomer neurotoxicity

Chronic cladribine administration increases amyloid beta peptide generation and plaque burden in mice

Enhanced generation of intracellular Aβ42 amyloid peptide by mutation of presenilins PS1 and PS2

Homocysteic acid induces intraneuronal accumulation of neurotoxic Aβ42: Implications for the pathogenesis of Alzheimer's disease

Amyloid beta-protein and lipid rafts: focused on biogenesis and catabolism

Meet Our Editorial Board Member

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