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Single-cell genomic approaches for developing the next generation of immunotherapies

Nature medicine, 2020-02, Vol.26 (2), p.171-177

2020

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The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway

Cell, 2020-06, Vol.181 (6), p.1207-1217

2020

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Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries

Cell, 2018-01, Vol.172 (1-2), p.14-21

2018

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Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

Cell, 2018-05, Vol.173 (5), p.1073-1081

2018

Volltextzugriff (PDF)

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

Nature medicine, 2020-06, Vol.26 (6), p.842-844

2020

Volltextzugriff (PDF)

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

Science (American Association for the Advancement of Science), 2014-02, Vol.343 (6172), p.776-779

2014

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Dissecting cellular crosstalk by sequencing physically interacting cells

Nature biotechnology, 2020-05, Vol.38 (5), p.629-637

2020

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Impaired immune surveillance accelerates accumulation of senescent cells and aging

Nature communications, 2018-12, Vol.9 (1), p.5435-15, Article 5435

2018

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Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

Science (American Association for the Advancement of Science), 2017-12, Vol.358 (6370), p.1622-1627

2017

Volltextzugriff (PDF)

Plasmacytoid dendritic cells develop from Ly6D + lymphoid progenitors distinct from the myeloid lineage

Nature immunology, 2019-07, Vol.20 (7), p.852

2019

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Cell composition analysis of bulk genomics using single-cell data

Nature methods, 2019-04, Vol.16 (4), p.327

2019

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Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

Cell, 2020-06, Vol.181 (7), p.1475-1488.e12

2020

Volltextzugriff (PDF)

PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model

Nature communications, 2019-01, Vol.10 (1), p.465-465, Article 465

2019

Volltextzugriff (PDF)

Clump sequencing exposes the spatial expression programs of intestinal secretory cells

Nature communications, 2021-05, Vol.12 (1), p.3074-3074, Article 3074

2021

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Full-length transcriptome assembly from RNA-Seq data without a reference genome

Nature biotechnology, 2011-07, Vol.29 (7), p.644-652

2011

Volltextzugriff (PDF)

MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing

Nature protocols, 2019-06, Vol.14 (6), p.1841-1862

2019

Volltextzugriff (PDF)

Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C− Cells

Immunity (Cambridge, Mass.), 2017-05, Vol.46 (5), p.849-862.e7

2017

Volltextzugriff (PDF)

Deciphering the state of immune silence in fatal COVID-19 patients

Nature communications, 2021-03, Vol.12 (1), p.1428-1428, Article 1428

2021

Volltextzugriff (PDF)

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

Cell, 2019-07, Vol.178 (3), p.686-698.e14

2019

Volltextzugriff (PDF)

Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress

Molecular psychiatry, 2020-05, Vol.25 (5), p.1050-1067

2020

Volltextzugriff (PDF)

Microglia development follows a stepwise program to regulate brain homeostasis

Science (American Association for the Advancement of Science), 2016-08, Vol.353 (6301), p.789-789

2016

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Lgr5+ telocytes are a signaling source at the intestinal villus tip

Nature communications, 2020-04, Vol.11 (1), p.1936-1936, Article 1936

2020

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Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

Cell, 2018-11, Vol.175 (4), p.1031-1044.e18

2018

Volltextzugriff (PDF)

Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies

Immunity (Cambridge, Mass.), 2018-05, Vol.48 (5), p.951-962.e5

2018

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A shared disease-associated oligodendrocyte signature among multiple CNS pathologies

Nature neuroscience, 2022-07, Vol.25 (7), p.876

2022

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Single-cell genomic approaches for developing the next generation of immunotherapies

The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway

Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

Dissecting cellular crosstalk by sequencing physically interacting cells

Impaired immune surveillance accelerates accumulation of senescent cells and aging

Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

Plasmacytoid dendritic cells develop from Ly6D + lymphoid progenitors distinct from the myeloid lineage

Cell composition analysis of bulk genomics using single-cell data

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model

Clump sequencing exposes the spatial expression programs of intestinal secretory cells

Full-length transcriptome assembly from RNA-Seq data without a reference genome

MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing

Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C− Cells

Deciphering the state of immune silence in fatal COVID-19 patients

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress

Microglia development follows a stepwise program to regulate brain homeostasis

Lgr5+ telocytes are a signaling source at the intestinal villus tip

Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies

A shared disease-associated oligodendrocyte signature among multiple CNS pathologies

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