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Phosphatidylinositol 4,5-bisphosphate (PIP2) and Ca2+ are both required to open the Cl− channel TMEM16A

The Journal of biological chemistry, 2019-08, Vol.294 (33), p.12556-12564

2019

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Opposing roles of E3 ligases TRIM23 and TRIM21 in regulation of ion channel ANO1 protein levels

The Journal of biological chemistry, 2021-01, Vol.296, p.100738-100738, Article 100738

2021

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Matairesinoside, a novel inhibitor of TMEM16A ion channel, loaded with functional hydrogel for lung cancer treatment

International journal of biological macromolecules, 2024-04, Vol.264 (Pt 2), p.130618-130618, Article 130618

2024

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Recent advances in TMEM16A: Structure, function, and disease

Journal of cellular physiology, 2019-06, Vol.234 (6), p.7856-7873

2019

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The pharmacology of the TMEM16A channel: therapeutic opportunities

Trends in pharmacological sciences (Regular ed.), 2022-09, Vol.43 (9), p.712-725

2022

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Mechanical Stress Modulates Calcium-Activated-Chloride Currents in Differentiating Lens Cells

Frontiers in physiology, 2022-01, Vol.13, p.814651-814651

2022

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Multi-target tracheloside and doxorubicin combined treatment of lung adenocarcinoma

Biomedicine & pharmacotherapy, 2022-09, Vol.153, p.113392-113392, Article 113392

2022

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Inhibitory effect of daidzein on the calcium-activated chloride channel TMEM16A and its anti-lung adenocarcinoma activity

International journal of biological macromolecules, 2023-12, Vol.253, p.127261-127261, Article 127261

2023

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Activation of TMEM16A Ca2+-activated Cl− channels by ROCK1/moesin promotes breast cancer metastasis

Journal of advanced research, 2021-11, Vol.33, p.253-264

2021

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Oleic acid blocks the calcium-activated chloride channel TMEM16A/ANO1

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2022-05, Vol.1867 (5), p.159134-159134, Article 159134

2022

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TMEM16A and TMEM16B channel proteins generate Ca2+-activated Cl− current and regulate melatonin secretion in rat pineal glands

The Journal of biological chemistry, 2018-01, Vol.293 (3), p.995-1006

2018

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Gender-Dependent Phenotype in Polycystic Kidney Disease Is Determined by Differential Intracellular Ca2+ Signals

International journal of molecular sciences, 2021-06, Vol.22 (11), p.6019

2021

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Nephron-specific knockout of TMEM16A leads to reduced number of glomeruli and albuminuria

American journal of physiology. Renal physiology, 2018-12, Vol.315 (6), p.F1777-F1786

2018

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Extracellular glucose and dysfunctional insulin receptor signaling independently upregulate arterial smooth muscle TMEM16A expression

American Journal of Physiology: Cell Physiology, 2024-04, Vol.326 (4), p.C1237-C1247

2024

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Honokiol inhibits proliferation of colorectal cancer cells by targeting anoctamin 1/TMEM16A Ca2+‐activated Cl− channels

British journal of pharmacology, 2021-10, Vol.178 (20), p.4137-4154

2021

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Near-Infrared Light-Responsive Nanoinhibitors for Tumor Suppression through Targeting and Regulating Anion Channels

ACS applied materials & interfaces, 2022-07, Vol.14 (28), p.31715-31726

2022

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The Ca2+-activated chloride channel ANO1/TMEM16A: An emerging therapeutic target for epithelium-originated diseases?

Acta pharmaceutica Sinica. B, 2021-06, Vol.11 (6), p.1412-1433

2021

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Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension

Biochemical pharmacology, 2022-12, Vol.206, p.115320-115320, Article 115320

2022

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Anoctamin 1, a multi-modal player in pain and itch

Cell calcium (Edinburgh), 2024-11, Vol.123, p.102924, Article 102924

2024

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Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1

Cellular signalling, 2018-04, Vol.44, p.10-19

2018

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Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea

Phytochemistry (Oxford), 2020-11, Vol.179, p.112464-112464, Article 112464

2020

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Exploring the potential of cryptochlorogenic acid as a dietary adjuvant for multi-target combined lung cancer treatment

Phytomedicine (Stuttgart), 2024-09, Vol.132, p.155907, Article 155907

2024

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Nimodipine inhibits intestinal and aortic smooth muscle contraction by regulating Ca2+-activated Cl− channels

Toxicology and applied pharmacology, 2021-06, Vol.421, p.115543, Article 115543

2021

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Loss of PKD1 and PKD2 share common effects on intracellular Ca2+ signaling

Cell calcium (Edinburgh), 2021-07, Vol.97, p.102413, Article 102413

2021

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Arctigenin, a novel TMEM16A inhibitor for lung adenocarcinoma therapy

Pharmacological research, 2020-05, Vol.155, p.104721-104721, Article 104721

2020

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Phosphatidylinositol 4,5-bisphosphate (PIP2) and Ca2+ are both required to open the Cl− channel TMEM16A

Opposing roles of E3 ligases TRIM23 and TRIM21 in regulation of ion channel ANO1 protein levels

Matairesinoside, a novel inhibitor of TMEM16A ion channel, loaded with functional hydrogel for lung cancer treatment

Recent advances in TMEM16A: Structure, function, and disease

The pharmacology of the TMEM16A channel: therapeutic opportunities

Mechanical Stress Modulates Calcium-Activated-Chloride Currents in Differentiating Lens Cells

Multi-target tracheloside and doxorubicin combined treatment of lung adenocarcinoma

Inhibitory effect of daidzein on the calcium-activated chloride channel TMEM16A and its anti-lung adenocarcinoma activity

Activation of TMEM16A Ca2+-activated Cl− channels by ROCK1/moesin promotes breast cancer metastasis

Oleic acid blocks the calcium-activated chloride channel TMEM16A/ANO1

TMEM16A and TMEM16B channel proteins generate Ca2+-activated Cl− current and regulate melatonin secretion in rat pineal glands

Gender-Dependent Phenotype in Polycystic Kidney Disease Is Determined by Differential Intracellular Ca2+ Signals

Nephron-specific knockout of TMEM16A leads to reduced number of glomeruli and albuminuria

Extracellular glucose and dysfunctional insulin receptor signaling independently upregulate arterial smooth muscle TMEM16A expression

Honokiol inhibits proliferation of colorectal cancer cells by targeting anoctamin 1/TMEM16A Ca2+‐activated Cl− channels

Near-Infrared Light-Responsive Nanoinhibitors for Tumor Suppression through Targeting and Regulating Anion Channels

The Ca2+-activated chloride channel ANO1/TMEM16A: An emerging therapeutic target for epithelium-originated diseases?

Translational potential of targeting Anoctamin-1-Encoded Calcium-Activated chloride channels in hypertension

Anoctamin 1, a multi-modal player in pain and itch

Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1

Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea

Exploring the potential of cryptochlorogenic acid as a dietary adjuvant for multi-target combined lung cancer treatment

Nimodipine inhibits intestinal and aortic smooth muscle contraction by regulating Ca2+-activated Cl− channels

Loss of PKD1 and PKD2 share common effects on intracellular Ca2+ signaling

Arctigenin, a novel TMEM16A inhibitor for lung adenocarcinoma therapy

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