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Chitosan oligosaccharide: Biological activities and potential therapeutic applications

Pharmacology & therapeutics (Oxford), 2017-02, Vol.170, p.80-97

2017

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Chitin and Chitosan Derivatives as Biomaterial Resources for Biological and Biomedical Applications

Molecules (Basel, Switzerland), 2020-12, Vol.25 (24), p.5961

2020

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Deoxyelephantopin and Its Isomer Isodeoxyelephantopin: Anti-Cancer Natural Products with Multiple Modes of Action

Molecules (Basel, Switzerland), 2022-03, Vol.27 (7), p.2086

2022

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Potential Applications of Chitosan-Based Nanomaterials to Surpass the Gastrointestinal Physiological Obstacles and Enhance the Intestinal Drug Absorption

Pharmaceutics, 2021-06, Vol.13 (6), p.887

2021

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An agonist of a zinc-sensing receptor GPR39 enhances tight junction assembly in intestinal epithelial cells via an AMPK-dependent mechanism

European journal of pharmacology, 2019-01, Vol.842, p.306-313

2019

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Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: Therapeutic efficacy and possible mechanisms of action

Pharmacological research, 2012-07, Vol.66 (1), p.66-79

2012

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Novel Potential Application of Chitosan Oligosaccharide for Attenuation of Renal Cyst Growth in the Treatment of Polycystic Kidney Disease

Molecules (Basel, Switzerland), 2020-11, Vol.25 (23), p.5589

2020

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Activation of AMPK by chitosan oligosaccharide in intestinal epithelial cells: Mechanism of action and potential applications in intestinal disorders

Biochemical pharmacology, 2015-08, Vol.96 (3), p.225-236

2015

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Discovery of a novel chalcone derivative inhibiting CFTR chloride channel via AMPK activation and its anti-diarrheal application

Journal of pharmacological sciences, 2019-07, Vol.140 (3), p.273-283

2019

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Pharmacological stimulation of G–protein coupled receptor 40 alleviates cytokine-induced epithelial barrier disruption in airway epithelial Calu-3 cells

International immunopharmacology, 2019-08, Vol.73, p.353-361

2019

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Cholera: pathophysiology and emerging therapeutic targets

Future medicinal chemistry, 2013-05, Vol.5 (7), p.781

2013

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Chitosan Oligosaccharide Promotes Junction Barrier through Modulation of PI3K/AKT and ERK Signaling Intricate Interplay in T84 Cells

Polymers, 2023-03, Vol.15 (7), p.1681

2023

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A G-protein coupled receptor 39 agonist stimulates proliferation of keratinocytes via an ERK-dependent pathway

Biomedicine & pharmacotherapy, 2020-07, Vol.127, p.110160, Article 110160

2020

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Chitosan Oligosaccharide Prevents Afatinib-Induced Barrier Disruption and Chloride Secretion through Modulation of AMPK, PI3K/AKT, and ERK Signaling in T84 Cells

Polymers, 2022-10, Vol.14 (20), p.4255

2022

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Antispasmodic Effect of Asperidine B, a Pyrrolidine Derivative, through Inhibition of L-Type Ca2+ Channel in Rat Ileal Smooth Muscle

Molecules (Basel, Switzerland), 2021-09, Vol.26 (18), p.5492

2021

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Fructo-oligosaccharides alleviate inflammation-associated apoptosis of GLP-1 secreting L cells via inhibition of iNOS and cleaved caspase-3 expression

Journal of pharmacological sciences, 2020-06, Vol.143 (2), p.65-73

2020

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Discovery of a chalcone derivative as an anti-fibrotic agent targeting transforming growth factor-β1 signaling: Potential therapy of renal fibrosis

Biomedicine & pharmacotherapy, 2023-09, Vol.165, p.115098-115098, Article 115098

2023

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A prebiotic fructo-oligosaccharide promotes tight junction assembly in intestinal epithelial cells via an AMPK-dependent pathway

Biomedicine & pharmacotherapy, 2020-09, Vol.129, p.110415-110415, Article 110415

2020

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Fungus-Derived 3-Hydroxyterphenyllin and Candidusin A Ameliorate Palmitic Acid-Induced Human Podocyte Injury via Anti-Oxidative and Anti-Apoptotic Mechanisms

Molecules (Basel, Switzerland), 2022-03, Vol.27 (7), p.2109

2022

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Natural statin derivatives as potential therapy to reduce intestinal fluid loss in cholera

PLoS neglected tropical diseases, 2022-12, Vol.16 (12), p.e0010989-e0010989

2022

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Losartan and Sodium Nitroprusside Effectively Protect against Renal Impairments after Ischemia and Reperfusion in Rats

Biological and Pharmaceutical Bulletin, 2015/05/01, Vol.38(5), pp.753-762

2015

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GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt

Biomedicine & pharmacotherapy, 2023-12, Vol.168, p.115774-115774, Article 115774

2023

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A fungus-derived purpactin A as an inhibitor of TMEM16A chloride channels and mucin secretion in airway epithelial cells

Biomedicine & pharmacotherapy, 2021-07, Vol.139, p.111583-111583, Article 111583

2021

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A chalcone derivative retards renal cyst enlargement by inhibiting fluid secretion and cell proliferation in an in vitro model of polycystic kidney disease

Clinical and experimental nephrology, 2021-09, Vol.25 (9), p.944-952

2021

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Adenosine monophosphate-activated protein kinase activation and suppression of inflammatory response by cell stretching in rabbit synovial fibroblasts

Molecular and cellular biochemistry, 2016-12, Vol.423 (1-2), p.175-185

2016

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Chitosan oligosaccharide: Biological activities and potential therapeutic applications

Chitin and Chitosan Derivatives as Biomaterial Resources for Biological and Biomedical Applications

Deoxyelephantopin and Its Isomer Isodeoxyelephantopin: Anti-Cancer Natural Products with Multiple Modes of Action

Potential Applications of Chitosan-Based Nanomaterials to Surpass the Gastrointestinal Physiological Obstacles and Enhance the Intestinal Drug Absorption

An agonist of a zinc-sensing receptor GPR39 enhances tight junction assembly in intestinal epithelial cells via an AMPK-dependent mechanism

Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: Therapeutic efficacy and possible mechanisms of action

Novel Potential Application of Chitosan Oligosaccharide for Attenuation of Renal Cyst Growth in the Treatment of Polycystic Kidney Disease

Activation of AMPK by chitosan oligosaccharide in intestinal epithelial cells: Mechanism of action and potential applications in intestinal disorders

Discovery of a novel chalcone derivative inhibiting CFTR chloride channel via AMPK activation and its anti-diarrheal application

Pharmacological stimulation of G–protein coupled receptor 40 alleviates cytokine-induced epithelial barrier disruption in airway epithelial Calu-3 cells

Cholera: pathophysiology and emerging therapeutic targets

Chitosan Oligosaccharide Promotes Junction Barrier through Modulation of PI3K/AKT and ERK Signaling Intricate Interplay in T84 Cells

A G-protein coupled receptor 39 agonist stimulates proliferation of keratinocytes via an ERK-dependent pathway

Chitosan Oligosaccharide Prevents Afatinib-Induced Barrier Disruption and Chloride Secretion through Modulation of AMPK, PI3K/AKT, and ERK Signaling in T84 Cells

Antispasmodic Effect of Asperidine B, a Pyrrolidine Derivative, through Inhibition of L-Type Ca2+ Channel in Rat Ileal Smooth Muscle

Fructo-oligosaccharides alleviate inflammation-associated apoptosis of GLP-1 secreting L cells via inhibition of iNOS and cleaved caspase-3 expression

Discovery of a chalcone derivative as an anti-fibrotic agent targeting transforming growth factor-β1 signaling: Potential therapy of renal fibrosis

A prebiotic fructo-oligosaccharide promotes tight junction assembly in intestinal epithelial cells via an AMPK-dependent pathway

Fungus-Derived 3-Hydroxyterphenyllin and Candidusin A Ameliorate Palmitic Acid-Induced Human Podocyte Injury via Anti-Oxidative and Anti-Apoptotic Mechanisms

Natural statin derivatives as potential therapy to reduce intestinal fluid loss in cholera

Losartan and Sodium Nitroprusside Effectively Protect against Renal Impairments after Ischemia and Reperfusion in Rats

GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt

A fungus-derived purpactin A as an inhibitor of TMEM16A chloride channels and mucin secretion in airway epithelial cells

A chalcone derivative retards renal cyst enlargement by inhibiting fluid secretion and cell proliferation in an in vitro model of polycystic kidney disease

Adenosine monophosphate-activated protein kinase activation and suppression of inflammatory response by cell stretching in rabbit synovial fibroblasts

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