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Radiation Sensitization of Basal Cell and Head and Neck Squamous Cell Carcinoma by the Hedgehog Pathway Inhibitor Vismodegib

International journal of molecular sciences, 2018-08, Vol.19 (9), p.2485

2018

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Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer

Nature reviews. Urology, 2014-07, Vol.11 (7), p.400-410

2014

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SET Domain-Containing Protein 4 Epigenetically Controls Breast Cancer Stem Cell Quiescence

Cancer research (Chicago, Ill.), 2019-09, Vol.79 (18), p.4729-4743

2019

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RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors

Cancer research (Chicago, Ill.), 2015-09, Vol.75 (17), p.3623-3635

2015

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Advanced basal cell carcinoma: What dermatologists need to know about diagnosis

Journal of the American Academy of Dermatology, 2022-06, Vol.86 (6), p.S1-S13

2022

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New common variants affecting susceptibility to basal cell carcinoma

Nature genetics, 2009-08, Vol.41 (8), p.909-914

2009

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Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors

Cancer cell, 2011-03, Vol.19 (3), p.401-415

2011

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miRNA expression profiles of premalignant and malignant arsenic-induced skin lesions

PloS one, 2018-08, Vol.13 (8), p.e0202579

2018

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Smoothened (SMO) receptor mutations dictate resistance to vismodegib in basal cell carcinoma

Molecular oncology, 2015-02, Vol.9 (2), p.389-397

2015

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Loss of Primary Cilia Drives Switching from Hedgehog to Ras/MAPK Pathway in Resistant Basal Cell Carcinoma

Journal of investigative dermatology, 2019-07, Vol.139 (7), p.1439-1448

2019

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Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

The New England journal of medicine, 2009-09, Vol.361 (12), p.1164-1172

2009

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Transcriptomic analysis of genes associated with vitamin D receptor signalling reveals differences between skin cancers

Experimental dermatology, 2024-10, Vol.33 (10), p.e15160-n/a

2024

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Causal association between skin cancer and immune cells: mendelian randomization (MR) study

BMC cancer, 2024-07, Vol.24 (1), p.849-12, Article 849

2024

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Molecular testing in metastatic basal cell carcinoma

Journal of the American Academy of Dermatology, 2021-11, Vol.85 (5), p.1135-1142

2021

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Genetic and functional interaction network analysis reveals global enrichment of regulatory T cell genes influencing basal cell carcinoma susceptibility

Genome medicine, 2021-02, Vol.13 (1), p.19-19, Article 19

2021

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Molecular pathology of skin neoplasms of the head and neck

Archives of pathology & laboratory medicine (1976), 2014-06, Vol.138 (6), p.759-787

2014

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FDA Approval Summary: Sonidegib for Locally Advanced Basal Cell Carcinoma

Clinical cancer research, 2017-05, Vol.23 (10), p.2377-2381

2017

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A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors

Clinical cancer research, 2014-04, Vol.20 (7), p.1900-1909

2014

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Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε

Molecular cell, 2020-11, Vol.80 (4), p.682-698.e7

2020

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FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors

Breast cancer research : BCR, 2020-06, Vol.22 (1), p.59-15, Article 59

2020

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Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond

Molecular carcinogenesis, 2017-12, Vol.56 (12), p.2543-2557

2017

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A Mammary Stem Cell Population Identified and Characterized in Late Embryogenesis Reveals Similarities to Human Breast Cancer

Cell stem cell, 2012-02, Vol.10 (2), p.183-197

2012

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Non-clinical evaluation of pmIL12 gene therapy for approval of the phase I clinical study

Scientific reports, 2024-09, Vol.14 (1), p.22288-13, Article 22288

2024

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An Investigator-Initiated Open-Label Trial of Sonidegib in Advanced Basal Cell Carcinoma Patients Resistant to Vismodegib

Clinical cancer research, 2016-03, Vol.22 (6), p.1325-1329

2016

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The causal relationship between immune cells mediating FIT3L, CCL4, OSM, and skin‐derived deteriorated tumors

Skin research and technology, 2024-07, Vol.30 (7), p.e13774-n/a

2024

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Radiation Sensitization of Basal Cell and Head and Neck Squamous Cell Carcinoma by the Hedgehog Pathway Inhibitor Vismodegib

Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer

SET Domain-Containing Protein 4 Epigenetically Controls Breast Cancer Stem Cell Quiescence

RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors

Advanced basal cell carcinoma: What dermatologists need to know about diagnosis

New common variants affecting susceptibility to basal cell carcinoma

Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors

miRNA expression profiles of premalignant and malignant arsenic-induced skin lesions

Smoothened (SMO) receptor mutations dictate resistance to vismodegib in basal cell carcinoma

Loss of Primary Cilia Drives Switching from Hedgehog to Ras/MAPK Pathway in Resistant Basal Cell Carcinoma

Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

Transcriptomic analysis of genes associated with vitamin D receptor signalling reveals differences between skin cancers

Causal association between skin cancer and immune cells: mendelian randomization (MR) study

Molecular testing in metastatic basal cell carcinoma

Genetic and functional interaction network analysis reveals global enrichment of regulatory T cell genes influencing basal cell carcinoma susceptibility

Molecular pathology of skin neoplasms of the head and neck

FDA Approval Summary: Sonidegib for Locally Advanced Basal Cell Carcinoma

A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors

Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε

FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors

Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond

A Mammary Stem Cell Population Identified and Characterized in Late Embryogenesis Reveals Similarities to Human Breast Cancer

Non-clinical evaluation of pmIL12 gene therapy for approval of the phase I clinical study

An Investigator-Initiated Open-Label Trial of Sonidegib in Advanced Basal Cell Carcinoma Patients Resistant to Vismodegib

The causal relationship between immune cells mediating FIT3L, CCL4, OSM, and skin‐derived deteriorated tumors

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