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Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors

The Journal of physiology, 1998-07, Vol.510 (1), p.1-18

1998

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Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1

eLife, 2017-07, Vol.6

2017

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Functional properties of in vitro excitatory cortical neurons derived from human pluripotent stem cells

The Journal of physiology, 2016-11, Vol.594 (22), p.6573-6582

2016

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Mechanism of Partial Agonism at NMDA Receptors for a Conformationally Restricted Glutamate Analog

The Journal of neuroscience, 2005-08, Vol.25 (34), p.7858-7866

2005

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Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

The Journal of physiology, 2008-01, Vol.586 (1), p.211-225

2008

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Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

Journal of neurochemistry, 2012-08, Vol.122 (4), p.738-751

2012

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Equilibrium Constants for (R)-[(S)-1-(4-Bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic Acid (NVP-AAM077) Acting at Recombinant NR1/NR2A and NR1/NR2B N-Methyl-d-aspartate Receptors: Implications for Studies of Synaptic Transmission

Molecular pharmacology, 2006-09, Vol.70 (3), p.1022-1032

2006

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Transplanted t(1;11) patient-derived OPCs form shorter myelin internodes in the hypomyelinated shiverer mice

Molecular psychiatry, 2019-11, Vol.24 (11), p.1567-1567

2019

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Phosphatidylinositol 3 Kinase Activation and AMPA Receptor Subunit Trafficking Underlie the Potentiation of Miniature EPSC Amplitudes Triggered by the Activation of L-Type Calcium Channels

The Journal of neuroscience, 2006-05, Vol.26 (20), p.5456-5469

2006

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Ionotropic glutamate receptors: structure, function and dysfunction

The Journal of physiology, 2022-01, Vol.600 (2), p.175-179

2022

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Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure

Neuropharmacology, 2013-11, Vol.74, p.119-125

2013

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Pharmacological insights obtained from structure–function studies of ionotropic glutamate receptors

British journal of pharmacology, 2006-04, Vol.147 (8), p.839-853

2006

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Loss of protohaem IX farnesyltransferase in mature dentate granule cells impairs short‐term facilitation at mossy fibre to CA3 pyramidal cell synapses

The Journal of physiology, 2017-03, Vol.595 (6), p.2147-2160

2017

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NMDA receptor function in inhibitory neurons

Neuropharmacology, 2021-09, Vol.196, p.108609-108609, Article 108609

2021

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Thesis write‐up and manuscript preparation: related but distinct tasks

The Journal of physiology, 2021-06, Vol.599 (11), p.2771-2775

Wyllie, David J. A.

2021

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3-Fluoro-N-methyl-D-aspartic acid (3F-NMDA) Stereoisomers as Conformational Probes for Exploring Agonist Binding at NMDA Receptors

Chemistry : a European journal, 2012-07, Vol.18 (28), p.8813-8819

2012

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Structural Features of the Glutamate Binding Site in Recombinant NR1/NR2A N-Methyl-d-aspartate Receptors Determined by Site-Directed Mutagenesis and Molecular Modeling

Molecular pharmacology, 2005-05, Vol.67 (5), p.1470-1484

2005

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Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers

Organic & biomolecular chemistry, 2017-03, Vol.15 (9), p.2086-2096

2017

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Slow deactivation kinetics of NMDA receptors containing NR1 and NR2D subunits in rat cerebellar Purkinje cells

The Journal of physiology, 2000-06, Vol.525 (2), p.299-305

2000

Volltextzugriff (PDF)

Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell‐derived excitatory cortical neurones

The Journal of physiology, 2014-10, Vol.592 (19), p.4353-4363

2014

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Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

Nature communications, 2015-05, Vol.6 (1), p.7066-7066, Article 7066

2015

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Single-channel analysis of a point mutation of a conserved serine residue in the S2 ligand-binding domain of the NR2A NMDA receptor subunit

The Journal of physiology, 2006-07, Vol.574 (2), p.477-489

2006

Volltextzugriff (PDF)

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

Nature neuroscience, 2008-04, Vol.11 (4), p.476-487

2008

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Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS

Human molecular genetics, 2015-11, Vol.24 (21), p.5977-5984

2015

Volltextzugriff (PDF)

Modelling the details: integrating structure with function

The Journal of physiology, 2018-09, Vol.596 (17), p.3833-3834

Wyllie, David J. A.

2018

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Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors

Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1

Functional properties of in vitro excitatory cortical neurons derived from human pluripotent stem cells

Mechanism of Partial Agonism at NMDA Receptors for a Conformationally Restricted Glutamate Analog

Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

Equilibrium Constants for (R)-[(S)-1-(4-Bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic Acid (NVP-AAM077) Acting at Recombinant NR1/NR2A and NR1/NR2B N-Methyl-d-aspartate Receptors: Implications for Studies of Synaptic Transmission

Transplanted t(1;11) patient-derived OPCs form shorter myelin internodes in the hypomyelinated shiverer mice

Phosphatidylinositol 3 Kinase Activation and AMPA Receptor Subunit Trafficking Underlie the Potentiation of Miniature EPSC Amplitudes Triggered by the Activation of L-Type Calcium Channels

Ionotropic glutamate receptors: structure, function and dysfunction

Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure

Pharmacological insights obtained from structure–function studies of ionotropic glutamate receptors

Loss of protohaem IX farnesyltransferase in mature dentate granule cells impairs short‐term facilitation at mossy fibre to CA3 pyramidal cell synapses

NMDA receptor function in inhibitory neurons

Thesis write‐up and manuscript preparation: related but distinct tasks

3-Fluoro-N-methyl-D-aspartic acid (3F-NMDA) Stereoisomers as Conformational Probes for Exploring Agonist Binding at NMDA Receptors

Structural Features of the Glutamate Binding Site in Recombinant NR1/NR2A N-Methyl-d-aspartate Receptors Determined by Site-Directed Mutagenesis and Molecular Modeling

Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers

Slow deactivation kinetics of NMDA receptors containing NR1 and NR2D subunits in rat cerebellar Purkinje cells

Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell‐derived excitatory cortical neurones

Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

Single-channel analysis of a point mutation of a conserved serine residue in the S2 ligand-binding domain of the NR2A NMDA receptor subunit

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS

Modelling the details: integrating structure with function

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