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Abstract 1884: HFB9-2, a novel Galectin 9 neutralizing antibody for the treatment of AML and other cancers

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1884-1884

2021

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Abstract 1883: Mechanism of action and biomarker strategy for HFB200301, an anti-TNFR2 agonist antibody for the treatment of cancer

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1883-1883

2021

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Abstract 6202: Integrating public single-cell transcriptomics and patient profiles to guide clinical development

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.6202-6202

2024

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Abstract 2285: HFB10-1E1, a novel OX-40 agonistic antibody with a unique pharmacological profile and biomarker strategy

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.2285-2285

2020

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Abstract 4248: HFB200603, a novel anti-BTLA monoclonal antibody that provides therapeutic potential for immune escape and synergizes with anti-PD-1 treatment

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.4248-4248

2022

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pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila

Nature (London), 1997-02, Vol.385 (6619), p.829-833

1997

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Abstract 618: Discovery of predictive biomarkers of response to T cell-targeting biologics using ex vivo single-cell profiling coupled with TCR clonotype characterization

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.618-618

2022

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Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors

BMC cell biology, 2003-05, Vol.4 (1), p.4, Article 4

2003

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Abstract 2489: Sensitivity of liver cancer cell lines to B-catenin knock-down correlates with pathway activation

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2489-2489

2018

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Oncogenic dependency on β-catenin in liver cancer cell lines correlates with pathway activation

Oncotarget, 2017-12, Vol.8 (70), p.114526-114539

2017

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Abstract 3477: Maximizing the outcome of CD226 stimulation through targeting beyond TIGIT signaling with combination and multi-specific approaches for cancer immunotherapy

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.3477-3477

2023

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The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens

BMC cell biology, 2008-01, Vol.9 (1), p.4, Article 4

2008

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Abstract 2899: Targeting regulatory T cells with HFB101110, a novel anti-human CCR8 antibody for the treatment of solid tumors

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2899-2899

2022

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Development of a Human Whole Blood Screening Platform to Monitor JAK/STAT Signaling Using High-Throughput Flow Cytometry

Journal of biomolecular screening, 2016-09, Vol.21 (8), p.866-874

2016

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Discovery of BMS-641988, a Novel and Potent Inhibitor of Androgen Receptor Signaling for the Treatment of Prostate Cancer

Cancer research (Chicago, Ill.), 2009-08, Vol.69 (16), p.6522-6530

2009

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Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer

ACS medicinal chemistry letters, 2015-08, Vol.6 (8), p.908-912

2015

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Establishing a high-throughput and automated cancer cell proliferation panel for oncology lead optimization

Journal of biomolecular screening, 2013-10, Vol.18 (9), p.1043-1053

2013

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Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (24), p.7516-7521

2011

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Wnt signals across the plasma membrane to activate the Î²-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP

Development (Cambridge), 2004-10, Vol.131 (20), p.5103

2004

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Casein kinase Iepsilon modulates the signaling specificities of dishevelled

Molecular and cellular biology, 2004-03, Vol.24 (5), p.2000-2011

2004

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Casein Kinase Iɛ Modulates the Signaling Specificities of Dishevelled

Molecular and cellular biology, 2004-03, Vol.24 (5), p.2000-2011

2004

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Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.02,6]undec-4-yl]-2-trifluoromethyl-benzonitriles as androgen receptor antagonists

Bioorganic & medicinal chemistry letters, 2010-08, Vol.20 (15), p.4491-4495

2010

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Abstract 5782: Androgen receptor antagonists: Lead optimization and preclinical pharmacology

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.5782-5782

2010

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Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.02,6]undec4-yl]-2-trifluoromethyl-benzonitriles as androgen receptor antagonists

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (15), p.4491-4495

2010

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The Protein 4.1, Ezrin, Radixin, Moesin (FERM) Domain of Drosophila Coracle, a Cytoplasmic Component of the Septate Junction, Provides Functions Essential for Embryonic Development and Imaginal Cell Proliferation

Genetics (Austin), 2001-09, Vol.159 (1), p.219-228

2001

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Abstract 1884: HFB9-2, a novel Galectin 9 neutralizing antibody for the treatment of AML and other cancers

Abstract 1883: Mechanism of action and biomarker strategy for HFB200301, an anti-TNFR2 agonist antibody for the treatment of cancer

Abstract 6202: Integrating public single-cell transcriptomics and patient profiles to guide clinical development

Abstract 2285: HFB10-1E1, a novel OX-40 agonistic antibody with a unique pharmacological profile and biomarker strategy

Abstract 4248: HFB200603, a novel anti-BTLA monoclonal antibody that provides therapeutic potential for immune escape and synergizes with anti-PD-1 treatment

pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila

Abstract 618: Discovery of predictive biomarkers of response to T cell-targeting biologics using ex vivo single-cell profiling coupled with TCR clonotype characterization

Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors

Abstract 2489: Sensitivity of liver cancer cell lines to B-catenin knock-down correlates with pathway activation

Oncogenic dependency on β-catenin in liver cancer cell lines correlates with pathway activation

Abstract 3477: Maximizing the outcome of CD226 stimulation through targeting beyond TIGIT signaling with combination and multi-specific approaches for cancer immunotherapy

The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens

Abstract 2899: Targeting regulatory T cells with HFB101110, a novel anti-human CCR8 antibody for the treatment of solid tumors

Development of a Human Whole Blood Screening Platform to Monitor JAK/STAT Signaling Using High-Throughput Flow Cytometry

Discovery of BMS-641988, a Novel and Potent Inhibitor of Androgen Receptor Signaling for the Treatment of Prostate Cancer

Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer

Establishing a high-throughput and automated cancer cell proliferation panel for oncology lead optimization

Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors

Wnt signals across the plasma membrane to activate the Î²-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP

Casein kinase Iepsilon modulates the signaling specificities of dishevelled

Casein Kinase Iɛ Modulates the Signaling Specificities of Dishevelled

Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.02,6]undec-4-yl]-2-trifluoromethyl-benzonitriles as androgen receptor antagonists

Abstract 5782: Androgen receptor antagonists: Lead optimization and preclinical pharmacology

Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.02,6]undec4-yl]-2-trifluoromethyl-benzonitriles as androgen receptor antagonists

The Protein 4.1, Ezrin, Radixin, Moesin (FERM) Domain of Drosophila Coracle, a Cytoplasmic Component of the Septate Junction, Provides Functions Essential for Embryonic Development and Imaginal Cell Proliferation

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