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Exploring Chemical Diversity of Epoxyquinoid Natural Products: Synthesis and Biological Activity of (−)-Jesterone and Related Molecules

Organic letters, 2001-05, Vol.3 (11), p.1649-1652

2001

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A practical strategy for the synthesis of 2-dialkylamino-4-arylamino-6-aminopyrimidines

Tetrahedron letters, 2009-10, Vol.50 (43), p.5888-5893

2009

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Synthesis of Epoxyquinol A and Related Molecules: Probing Chemical Reactivity of Epoxyquinol Dimers and 2H-Pyran Precursors

Journal of organic chemistry, 2005-07, Vol.70 (15), p.6053-6065

2005

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Common Variants in the ARG1 Gene Contribute to the Risk of Dilated Cardiomyopathy in the Han Chinese Population

Genetic testing and molecular biomarkers, 2020-09, Vol.24 (9), p.584-591

2020

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Discovery of MK-4688: an Efficient Inhibitor of the HDM2–p53 Protein–Protein Interaction

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.16213-16241

2021

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Sulfone Displacement Approach for Large-Scale Synthesis of 4‑Chloro‑N‑(1-methyl‑1H‑pyrazol-4-yl)pyrimidin-2-amine

Organic process research & development, 2022-01, Vol.26 (1), p.137-143

2022

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Process Development and Large-Scale Synthesis of BTK Inhibitor BIIB068

Organic process research & development, 2020-06, Vol.24 (6), p.1199-1206

2020

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Projected Dose Optimization of Amino- and Hydroxypyrrolidine Purine PI3Kδ Immunomodulators

Journal of medicinal chemistry, 2021-04, Vol.64 (8), p.5137-5156

2021

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Discovery and optimization of heteroaryl piperazines as potent and selective PI3Kδ inhibitors

Bioorganic & medicinal chemistry letters, 2020-01, Vol.30 (1), p.126715, Article 126715

2020

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Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability

Journal of medicinal chemistry, 2019-05, Vol.62 (9), p.4370-4382

2019

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Synthesis and evaluation of an N-[18F]fluorodeoxyglycosyl amino acid for PET imaging of tumor metabolism

Nuclear medicine and biology, 2018-11, Vol.66, p.40-48

2018

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Synthesis and biologic assessment of N-^sup 18^F-fluorodeoxyglycosyl amino acid as potential multi-targeted agent for tumor metabolism PET imaging

The Journal of nuclear medicine (1978), 2017-05, Vol.58, p.937

2017

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A Comparison of Doxycycline and Amoxicillin Containing Quadruple Eradication Therapy for Treating IHelicobacter pylori/I-Infected Duodenal Ulcers: A Multicenter, Opened, Randomized Controlled Trial in China

Pathogens (Basel), 2022-12, Vol.11 (12)

2022

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Abstract 2254: Solid tumor activity with a selective PI3Kdelta inhibitor as a single agent and in combination with anti-PD-1

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2254-2254

2019

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Evolution characters of water exchange abilities between Dongting Lake and Yangtze River

Journal of geographical sciences, 2014-08, Vol.24 (4), p.731-745

2014

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Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (12), p.2721-2726

2017

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Process Safety Considerations for the Supply of a High-Energy Oxadiazole IDO1-Selective Inhibitor

Organic process research & development, 2019-06, Vol.23 (6), p.1178-1190

2019

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Effects of the dispatch modes of the Three Gorges Reservoir on the water regimes in the Dongting Lake area in typical years

Journal of geographical sciences, 2012-08, Vol.22 (4), p.594-608

2012

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Total Synthesis of the Quinone Epoxide Dimer (+)-Torreyanic Acid: Application of a Biomimetic Oxidation/Electrocyclization/Diels−Alder Dimerization Cascade1

Journal of the American Chemical Society, 2003-04, Vol.125 (17), p.5095-5106

2003

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Responsible AI: The Revolution in Governance Technology in China

2021 2nd International Conference on Artificial Intelligence and Education (ICAIE), 2021, p.76-80

2021

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On the Rearrangement of an Azaspiroindolenine to a Precursor to Phalarine: Mechanistic Insights

Angewandte Chemie, 2007-02, Vol.119 (9), p.1466-1469

2007

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Potent benzoazepinone γ-secretase modulators with improved bioavailability

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3495-3500

2015

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Synthesis of Epoxyquinol A and Related Molecules: Probing Chemical Reactivity of Epoxyquinol Dimers and 2 H -Pyran Precursors

Journal of organic chemistry, 2005-07, Vol.70 (15), p.6053-6065

2005

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Studies directed toward the synthesis of the guanidine alkaloid, spiroleucettadine: some observations at the level of structure

Tetrahedron letters, 2006-01, Vol.47 (3), p.385-387

2006

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Exploring Chemical Diversity of Epoxyquinoid Natural Products: Synthesis and Biological Activity of (−)-Jesterone and Related Molecules

A practical strategy for the synthesis of 2-dialkylamino-4-arylamino-6-aminopyrimidines

Synthesis of Epoxyquinol A and Related Molecules: Probing Chemical Reactivity of Epoxyquinol Dimers and 2H-Pyran Precursors

Common Variants in the ARG1 Gene Contribute to the Risk of Dilated Cardiomyopathy in the Han Chinese Population

Discovery of MK-4688: an Efficient Inhibitor of the HDM2–p53 Protein–Protein Interaction

Sulfone Displacement Approach for Large-Scale Synthesis of 4‑Chloro‑N‑(1-methyl‑1H‑pyrazol-4-yl)pyrimidin-2-amine

Process Development and Large-Scale Synthesis of BTK Inhibitor BIIB068

Projected Dose Optimization of Amino- and Hydroxypyrrolidine Purine PI3Kδ Immunomodulators

Discovery and optimization of heteroaryl piperazines as potent and selective PI3Kδ inhibitors

Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability

Synthesis and evaluation of an N-[18F]fluorodeoxyglycosyl amino acid for PET imaging of tumor metabolism

Synthesis and biologic assessment of N-^sup 18^F-fluorodeoxyglycosyl amino acid as potential multi-targeted agent for tumor metabolism PET imaging

A Comparison of Doxycycline and Amoxicillin Containing Quadruple Eradication Therapy for Treating IHelicobacter pylori/I-Infected Duodenal Ulcers: A Multicenter, Opened, Randomized Controlled Trial in China

Abstract 2254: Solid tumor activity with a selective PI3Kdelta inhibitor as a single agent and in combination with anti-PD-1

Evolution characters of water exchange abilities between Dongting Lake and Yangtze River

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation

Process Safety Considerations for the Supply of a High-Energy Oxadiazole IDO1-Selective Inhibitor

Effects of the dispatch modes of the Three Gorges Reservoir on the water regimes in the Dongting Lake area in typical years

Total Synthesis of the Quinone Epoxide Dimer (+)-Torreyanic Acid: Application of a Biomimetic Oxidation/Electrocyclization/Diels−Alder Dimerization Cascade1

Discovery of 1‑[3-(1-Methyl‑1H‑pyrazol-4-yl)-5-oxo‑5H‑benzo[4,5]cyclohepta[1,2‑b]pyridin-7-yl]‑N‑(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c‑Met/Ron Dual Kinase Inhibitor with Preferential Affinity for the Activated State of c‑Met

Responsible AI: The Revolution in Governance Technology in China

On the Rearrangement of an Azaspiroindolenine to a Precursor to Phalarine: Mechanistic Insights

Potent benzoazepinone γ-secretase modulators with improved bioavailability

Synthesis of Epoxyquinol A and Related Molecules: Probing Chemical Reactivity of Epoxyquinol Dimers and 2 H -Pyran Precursors

Studies directed toward the synthesis of the guanidine alkaloid, spiroleucettadine: some observations at the level of structure

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