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High-Frequency Mutagenesis of Human Cells and Characterization of a Mutant Unresponsive to both α and γ Interferons

Proceedings of the National Academy of Sciences - PNAS, 1991-12, Vol.88 (24), p.11455-11459

1991

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Transcription Factor ISGF-3 Formation Requires Phosphorylated Stat91 Protein, But Stat113 Protein is Phosphorylated Independently of Stat91 Protein

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (11), p.4776-4780

1994

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Signaling through a mutant IFN-gamma receptor

The Journal of immunology (1950), 2005-11, Vol.175 (9), p.5958-5965

2005

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Participation of JAK and STAT Proteins in Growth Hormone-induced Signaling (∗)

The Journal of biological chemistry, 1996-03, Vol.271 (10), p.5947-5952

1996

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A completely foreign receptor can mediate an interferon-γ-like response

The EMBO journal, 2001-10, Vol.20 (19), p.5431-5442

2001

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Receptor-Associated Constitutive Protein Tyrosine Phosphatase Activity Controls the Kinase Function of JAK1

Proceedings of the National Academy of Sciences - PNAS, 1997-08, Vol.94 (16), p.8563-8568

1997

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Analysis of Gene Expression Using High-Density and IFN-γ-Specific Low-Density cDNA Arrays

Genomics (San Diego, Calif.), 2001-09, Vol.77 (1-2), p.50-57

2001

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The JAK/STAT pathway is not sufficient to sustain the antiproliferative response in an interferon-resistant human melanoma cell line

Melanoma research, 2003-06, Vol.13 (3), p.219-229

2003

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Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells

Cell, 1984-10, Vol.38 (3), p.745-755

1984

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Inhibition of protein synthesis by 2′-5′ linked adenine oligonucleotides in intact cells

Nature (London), 1978-11, Vol.276 (5683), p.88-90

1978

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JAKs, STATs and signal transduction in response to the interferons and other cytokines

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 1996-02, Vol.351 (1336), p.167-171

1996

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Inhibition of the cellular response to interferons by products of the adenovirus type 5 E1A oncogene

Nucleic acids research, 1991-08, Vol.19 (16), p.4387-4393

1991

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Activation of Jak2 Catalytic Activity Requires Phosphorylation of Y 1007 in the Kinase Activation Loop

Molecular and cellular biology, 1997-05, Vol.17 (5), p.2497-2501

1997

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Molecular analysis of a human interferon‐inducible gene family

European journal of biochemistry, 1991-07, Vol.199 (2), p.417-423

1991

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Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon‐alpha and ‐gamma signal transduction pathways

The EMBO journal, 1993-11, Vol.12 (11), p.4221-4228

1993

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Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling

Molecular and Cellular Biology, 1997-04, Vol.17 (4), p.2048-2056

1997

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Interferon action--sequence specificity of the ppp(A2'p)nA-dependent ribonuclease

Nature (London), 1981-01, Vol.289 (5796), p.414-417

1981

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A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin‐6

The EMBO journal, 1995-04, Vol.14 (7), p.1421-1429

1995

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Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

Molecular and Cellular Biology, 1997-05, Vol.17 (5), p.2497-2501

1997

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Activation of JAK kinases and STAT proteins by interleukin‐2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes

The EMBO journal, 1994-12, Vol.13 (23), p.5605-5615

1994

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Synthesis of low molecular weight inhibitor of protein synthesis with enzyme from interferon-treated cells

Nature (London), 1977-08, Vol.268 (5620), p.537-540

1977

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Kinase‐negative mutants of JAK1 can sustain interferon‐gamma‐inducible gene expression but not an antiviral state

The EMBO journal, 1996-02, Vol.15 (4), p.799-809

1996

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P-STAT1 mediates higher-order chromatin remodelling of the human MHC in response to IFNgamma

Journal of cell science, 2007-09, Vol.120 (Pt 18), p.3262

2007

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Jak1 Plays an Essential Role for Receptor Phosphorylation and Stat Activation in Response to Granulocyte Colony-Stimulating Factor

Blood, 1997-07, Vol.90 (2), p.597-604

1997

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2-5A synthetase: assay, distribution and variation with growth or hormone status

Nature (London), 1979-03, Vol.278 (5703), p.471-473

1979

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High-Frequency Mutagenesis of Human Cells and Characterization of a Mutant Unresponsive to both α and γ Interferons

Transcription Factor ISGF-3 Formation Requires Phosphorylated Stat91 Protein, But Stat113 Protein is Phosphorylated Independently of Stat91 Protein

Signaling through a mutant IFN-gamma receptor

Participation of JAK and STAT Proteins in Growth Hormone-induced Signaling (∗)

A completely foreign receptor can mediate an interferon-γ-like response

Receptor-Associated Constitutive Protein Tyrosine Phosphatase Activity Controls the Kinase Function of JAK1

Analysis of Gene Expression Using High-Density and IFN-γ-Specific Low-Density cDNA Arrays

The JAK/STAT pathway is not sufficient to sustain the antiproliferative response in an interferon-resistant human melanoma cell line

Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells

Inhibition of protein synthesis by 2′-5′ linked adenine oligonucleotides in intact cells

JAKs, STATs and signal transduction in response to the interferons and other cytokines

Inhibition of the cellular response to interferons by products of the adenovirus type 5 E1A oncogene

Activation of Jak2 Catalytic Activity Requires Phosphorylation of Y 1007 in the Kinase Activation Loop

Molecular analysis of a human interferon‐inducible gene family

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon‐alpha and ‐gamma signal transduction pathways

Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling

Interferon action--sequence specificity of the ppp(A2'p)nA-dependent ribonuclease

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin‐6

Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

Activation of JAK kinases and STAT proteins by interleukin‐2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes

Synthesis of low molecular weight inhibitor of protein synthesis with enzyme from interferon-treated cells

Kinase‐negative mutants of JAK1 can sustain interferon‐gamma‐inducible gene expression but not an antiviral state

P-STAT1 mediates higher-order chromatin remodelling of the human MHC in response to IFNgamma

Jak1 Plays an Essential Role for Receptor Phosphorylation and Stat Activation in Response to Granulocyte Colony-Stimulating Factor

2-5A synthetase: assay, distribution and variation with growth or hormone status

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