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The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride

Journal of the American Society of Nephrology, 2015-08, Vol.26 (8), p.1781-1786

2015

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WNK2 Kinase Is a Novel Regulator of Essential Neuronal Cation-Chloride Cotransporters

The Journal of biological chemistry, 2011-08, Vol.286 (34), p.30171-30180

2011

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WNK3 Bypasses the Tonicity Requirement for K-Cl Cotransporter Activation via a Phosphatase-Dependent Pathway

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (6), p.1976-1981

2006

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Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC

American journal of physiology. Renal physiology, 2018-09, Vol.315 (3), p.F734-F745

2018

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Pathophysiology of functional mutations of the thiazide-sensitive Na-Cl cotransporter in Gitelman disease

American journal of physiology. Renal physiology, 2004-08, Vol.287 (2), p.F195-F203

2004

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Insulin increases the functional activity of the renal NaCl cotransporter

Journal of hypertension, 2013-02, Vol.31 (2), p.303-311

2013

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Identification and functional characterization of cation–chloride cotransporters in plants

The Plant journal : for cell and molecular biology, 2007-04, Vol.50 (2), p.278-292

2007

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cAMP-dependent activation of the renal-specific Na+-K+-2Cl- cotransporter is mediated by regulation of cotransporter trafficking

American journal of physiology. Renal physiology, 2003-06, Vol.284 (6), p.F1145-F1154

2003

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WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4

Hypertension (Dallas, Tex. 1979), 2014-11, Vol.64 (5), p.1047-1053

2014

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Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway

Journal of the American Society of Nephrology, 2011-09, Vol.22 (9), p.1707-1719

2011

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N-terminal Serine Dephosphorylation Is Required for KCC3 Cotransporter Full Activation by Cell Swelling

The Journal of biological chemistry, 2013-11, Vol.288 (44), p.31468-31476

2013

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WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter

American journal of physiology. Renal physiology, 2014-08, Vol.307 (3), p.F275-F286

2014

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Geraniin is a diuretic by inhibiting the Na + -K + -2Cl - cotransporter NKCC2

American journal of physiology. Renal physiology, 2018-02, Vol.314 (2), p.F240-F250

2018

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Regulation of NKCC2 by a Chloride-Sensing Mechanism Involving the WNK3 and SPAK Kinases

Proceedings of the National Academy of Sciences - PNAS, 2008-06, Vol.105 (24), p.8458-8463

2008

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Similar effects of all WNK3 variants on SLC12 cotransporters

American Journal of Physiology: Cell Physiology, 2011-09, Vol.301 (3), p.C601-C608

2011

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Rare mutations in SLC12A1 and SLC12A3 protect against hypertension by reducing the activity of renal salt cotransporters

Journal of hypertension, 2011-03, Vol.29 (3), p.475-483

2011

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Alternatively spliced isoform of apical Na(+)-K(+)-Cl(-) cotransporter gene encodes a furosemide-sensitive Na(+)-Cl(-)cotransporter

American journal of physiology. Renal physiology, 2001-04, Vol.280 (4), p.F574-F582

2001

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WNK4 kinase is a negative regulator of K+-Cl- cotransporters

American journal of physiology. Renal physiology, 2007-04, Vol.292 (4), p.F1197-F1207

2007

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The Na+:Cl– Cotransporter Is Activated and Phosphorylated at the Amino-terminal Domain upon Intracellular Chloride Depletion

The Journal of biological chemistry, 2006-09, Vol.281 (39), p.28755-28763

2006

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With no lysine L-WNK1 isoforms are negative regulators of the K+-Cl- cotransporters

American Journal of Physiology: Cell Physiology, 2016-07, Vol.311 (1), p.C54-C66

2016

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NH2-terminal heterogeneity in the KCC3 K+-Cl- cotransporter

American journal of physiology. Renal physiology, 2005-12, Vol.289 (6), p.F1246-F1261

2005

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WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na+-Cl- cotransporter

American Journal of Physiology - Renal Physiology, 2008-10, Vol.295 (4), p.F1199-F1206

2008

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Functional Properties of the Apical Na+-K+-2Cl− Cotransporter Isoforms

The Journal of biological chemistry, 2002-03, Vol.277 (13), p.11004-11012

2002

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Affinity-defining domains in the Na-Cl cotransporter: a different location for Cl- and thiazide binding

The Journal of biological chemistry, 2006-06, Vol.281 (25), p.17266

2006

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A single residue in transmembrane domain 11 defines the different affinity for thiazides between the mammalian and flounder NaCl transporters

American journal of physiology. Renal physiology, 2010-11, Vol.299 (5), p.F1111-F1119

2010

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The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride

WNK2 Kinase Is a Novel Regulator of Essential Neuronal Cation-Chloride Cotransporters

WNK3 Bypasses the Tonicity Requirement for K-Cl Cotransporter Activation via a Phosphatase-Dependent Pathway

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC

Pathophysiology of functional mutations of the thiazide-sensitive Na-Cl cotransporter in Gitelman disease

Insulin increases the functional activity of the renal NaCl cotransporter

Identification and functional characterization of cation–chloride cotransporters in plants

cAMP-dependent activation of the renal-specific Na+-K+-2Cl- cotransporter is mediated by regulation of cotransporter trafficking

WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4

Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway

N-terminal Serine Dephosphorylation Is Required for KCC3 Cotransporter Full Activation by Cell Swelling

WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter

Geraniin is a diuretic by inhibiting the Na + -K + -2Cl - cotransporter NKCC2

Regulation of NKCC2 by a Chloride-Sensing Mechanism Involving the WNK3 and SPAK Kinases

Similar effects of all WNK3 variants on SLC12 cotransporters

Rare mutations in SLC12A1 and SLC12A3 protect against hypertension by reducing the activity of renal salt cotransporters

Alternatively spliced isoform of apical Na(+)-K(+)-Cl(-) cotransporter gene encodes a furosemide-sensitive Na(+)-Cl(-)cotransporter

WNK4 kinase is a negative regulator of K+-Cl- cotransporters

The Na+:Cl– Cotransporter Is Activated and Phosphorylated at the Amino-terminal Domain upon Intracellular Chloride Depletion

With no lysine L-WNK1 isoforms are negative regulators of the K+-Cl- cotransporters

NH2-terminal heterogeneity in the KCC3 K+-Cl- cotransporter

WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na+-Cl- cotransporter

Functional Properties of the Apical Na+-K+-2Cl− Cotransporter Isoforms

Affinity-defining domains in the Na-Cl cotransporter: a different location for Cl- and thiazide binding

A single residue in transmembrane domain 11 defines the different affinity for thiazides between the mammalian and flounder NaCl transporters

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